ES2008956A6 - Un procedimiebto para obtener una linea de celulas hibridas capaces deproducir anticuerpos monoclonales singularmente especificos de los neutrofilos humanos. - Google Patents
Un procedimiebto para obtener una linea de celulas hibridas capaces deproducir anticuerpos monoclonales singularmente especificos de los neutrofilos humanos.Info
- Publication number
- ES2008956A6 ES2008956A6 ES8800066A ES8800066A ES2008956A6 ES 2008956 A6 ES2008956 A6 ES 2008956A6 ES 8800066 A ES8800066 A ES 8800066A ES 8800066 A ES8800066 A ES 8800066A ES 2008956 A6 ES2008956 A6 ES 2008956A6
- Authority
- ES
- Spain
- Prior art keywords
- monoclonal antibody
- produced
- cell line
- derived
- antibody specific
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
UN PROCEDIMIENTO PARA OBTENER UNA LINEA DE CELULAS HIBRIDAS CAPACES DE PRODUCIR ANTICUERPOS MONOCLONALES SINGULARMENTE ESPECIFICOS DE LOS NEUTROFILOS HUMANOS, QUE COMPRENDE INMUNIZAR UN ANIMAL CON GRANULOCITOS HUMANOS, FUSIONAR CELULAS PRODUCTORAS DE ANTICUERPO DE ANIMAL INMUNIZADO CON CELULAS DE UNA LINEA CELULAR INMORTAL, CULTIVARLAS EN UN MEDIO SELECTIVO Y SELECCIONAR LAS QUE PRODUCEN EL ANTICUERPO MONOCLONAL QUE SE UNE ESPECIFICAMENTE AL ANTIGENO 103 DE NEUTROFILOS. SE DESCRIBE LA OBTENCION DE LOS CITADOS ANTICUERPOS POR CULTIVO DE LOS HIBRIDOMAS OBTENIDOS Y SEPARACION DEL ANTICUERPO. LA LINEA CELULAR HA SIDO DEPOSITADA EN LA ATCC CON EL N.G HB 9445. EL ANTICUERPO MONOCLONAL OBTENIDO NO TIENE NINGUNA REACTIVIDAD CON OTRAS CELULAS DE LA SANGRE PERIFERICA HUMANA Y PRACTICAMENTE NINGUNA REACTIVIDAD CON LOS PRECURSORES GRANULOCITICOS U OTRAS CELULAS DE LA MEDULA OSEA, NI CON CELULAS DE LA LEUCEMIA HUMANA AGUDA Y PUEDE SER UTILIZADO PARA ENUMERAR Y AISLAR NEUTROFILOS EN LA SANGRE.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/070,202 US4931395A (en) | 1986-12-08 | 1987-07-06 | Monoclonal antibody specific to neutrophils |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2008956A6 true ES2008956A6 (es) | 1989-08-16 |
Family
ID=22093802
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES8800066A Expired ES2008956A6 (es) | 1987-07-06 | 1988-01-12 | Un procedimiebto para obtener una linea de celulas hibridas capaces deproducir anticuerpos monoclonales singularmente especificos de los neutrofilos humanos. |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES2008956A6 (es) |
-
1988
- 1988-01-12 ES ES8800066A patent/ES2008956A6/es not_active Expired
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| SA6 | Expiration date (snapshot 920101) |
Free format text: 2008-01-12 |
|
| FD1A | Patent lapsed |
Effective date: 20020401 |