ES2009239A6 - Two step method for treating wound and aqueous medium and local ointment therefor - Google Patents
Two step method for treating wound and aqueous medium and local ointment thereforInfo
- Publication number
- ES2009239A6 ES2009239A6 ES8800576A ES8800576A ES2009239A6 ES 2009239 A6 ES2009239 A6 ES 2009239A6 ES 8800576 A ES8800576 A ES 8800576A ES 8800576 A ES8800576 A ES 8800576A ES 2009239 A6 ES2009239 A6 ES 2009239A6
- Authority
- ES
- Spain
- Prior art keywords
- ointment
- esp
- amino acids
- basic
- treating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002674 ointment Substances 0.000 title abstract 3
- 239000012736 aqueous medium Substances 0.000 title 1
- 206010052428 Wound Diseases 0.000 abstract 5
- 208000027418 Wounds and injury Diseases 0.000 abstract 4
- 150000001413 amino acids Chemical class 0.000 abstract 3
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 abstract 2
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 abstract 1
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 abstract 1
- 229930003270 Vitamin B Natural products 0.000 abstract 1
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 abstract 1
- 229910021502 aluminium hydroxide Inorganic materials 0.000 abstract 1
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 abstract 1
- 229940031955 anhydrous lanolin Drugs 0.000 abstract 1
- 239000003963 antioxidant agent Substances 0.000 abstract 1
- 230000003078 antioxidant effect Effects 0.000 abstract 1
- 235000006708 antioxidants Nutrition 0.000 abstract 1
- 235000010216 calcium carbonate Nutrition 0.000 abstract 1
- 229910000019 calcium carbonate Inorganic materials 0.000 abstract 1
- 239000002738 chelating agent Substances 0.000 abstract 1
- 229910001679 gibbsite Inorganic materials 0.000 abstract 1
- 239000008311 hydrophilic ointment Substances 0.000 abstract 1
- VTHJTEIRLNZDEV-UHFFFAOYSA-L magnesium dihydroxide Chemical compound [OH-].[OH-].[Mg+2] VTHJTEIRLNZDEV-UHFFFAOYSA-L 0.000 abstract 1
- 239000000347 magnesium hydroxide Substances 0.000 abstract 1
- 235000012254 magnesium hydroxide Nutrition 0.000 abstract 1
- 229910001862 magnesium hydroxide Inorganic materials 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 235000008160 pyridoxine Nutrition 0.000 abstract 1
- 239000011677 pyridoxine Substances 0.000 abstract 1
- 235000019155 vitamin A Nutrition 0.000 abstract 1
- 239000011719 vitamin A Substances 0.000 abstract 1
- 235000019156 vitamin B Nutrition 0.000 abstract 1
- 239000011720 vitamin B Substances 0.000 abstract 1
- 229940045997 vitamin a Drugs 0.000 abstract 1
- 229940011671 vitamin b6 Drugs 0.000 abstract 1
- 239000011592 zinc chloride Substances 0.000 abstract 1
- 235000005074 zinc chloride Nutrition 0.000 abstract 1
- JIAARYAFYJHUJI-UHFFFAOYSA-L zinc dichloride Chemical compound [Cl-].[Cl-].[Zn+2] JIAARYAFYJHUJI-UHFFFAOYSA-L 0.000 abstract 1
Landscapes
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Treatment of open wounds in human tissue (esp. skin) is effected by (a) treating the wound area with an aq. medium having a pH low enough to cause at least partial ionisation of basic amino acids naturally present in adjacent tissues and to bring them into soln. at the surface of the wound area, and (b) treating the wound area with a basic ointment having a pH high enough to activate amino acids at the surface of the wound. The aq. medium has a pH of 4.3-6.8 and contains a chelating agent for basic amino acids, esp. ZnCl2. It may also contain a vitamin B cpd. (esp. pyridoxine,HCl) and dexgtrose. The ointment has a pH of 6.5-9 and comprises a basic material (I), anhydrous lanolin, a hydrophilic ointment base and a water-soluble Zn salt, opt. together with vitamin A as antioxidant. (I) is pref. CaCO3, Mg(OH)2 or Al(OH)3. The concn. of the Zn salt is 0.15-15 wt.% based on (I).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/019,768 US4847083A (en) | 1986-04-02 | 1987-02-27 | Two-step procedure for indolent wound healing and aqueous medium and topical ointment used in connection therewith |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2009239A6 true ES2009239A6 (en) | 1989-09-16 |
Family
ID=21794935
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES8800576A Expired ES2009239A6 (en) | 1987-02-27 | 1988-02-26 | Two step method for treating wound and aqueous medium and local ointment therefor |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JP2693961B2 (en) |
| ES (1) | ES2009239A6 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2081771A1 (en) * | 1994-08-05 | 1996-03-01 | Arredondo Javier Olaechea | Composition of a liquid product for topical use for burns and bruises. |
-
1988
- 1988-02-26 ES ES8800576A patent/ES2009239A6/en not_active Expired
- 1988-02-27 JP JP63043339A patent/JP2693961B2/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2081771A1 (en) * | 1994-08-05 | 1996-03-01 | Arredondo Javier Olaechea | Composition of a liquid product for topical use for burns and bruises. |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS63307817A (en) | 1988-12-15 |
| JP2693961B2 (en) | 1997-12-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD2A | Announcement of lapse in spain |
Effective date: 20110302 |