ES2009366A6 - Procedimiento de obtencion de anticuerpos monoclonales para bacterias gram-negativas. - Google Patents

Procedimiento de obtencion de anticuerpos monoclonales para bacterias gram-negativas.

Info

Publication number
ES2009366A6
ES2009366A6 ES8803336A ES8803336A ES2009366A6 ES 2009366 A6 ES2009366 A6 ES 2009366A6 ES 8803336 A ES8803336 A ES 8803336A ES 8803336 A ES8803336 A ES 8803336A ES 2009366 A6 ES2009366 A6 ES 2009366A6
Authority
ES
Spain
Prior art keywords
monoclonal antibodies
negative bacteria
gram negative
lipopolysaccharide
gram
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8803336A
Other languages
English (en)
Inventor
Lowell S Young
Susan Alam
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
University of California Berkeley
Original Assignee
University of California
University of California Berkeley
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/855,878 external-priority patent/US4918163A/en
Application filed by University of California, University of California Berkeley filed Critical University of California
Publication of ES2009366A6 publication Critical patent/ES2009366A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Gram-negative bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Gram-negative bacteria
    • C07K16/1214—Pseudomonadaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/21—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Pseudomonadaceae (F)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/50—Lipopolysaccharides; LPS
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE ANTICUERPOS MONOCLONALES PARA BACTERIAS GRAM-NEGATIVAS, EN EL QUE SE CULTIVA UN HIBRIDOMA SELECCIONADO ENTRE XMMEN-J5D, NUMERO DE ADMISION A.T.C.C. HB 9083, XMMEN-OE5, NUMERO DE ADMISION A.T.C.C. HB 9081, XMMEN-LY1, NUMERO DE ADMISION A.T.C.C. HB 9082, XMMPS-OP1, NUMERO DE ADMISION A.T.C.C. HB 9384, EN UN MEDIO DE CULTIVO DE TEJIDOS, PARTICULARMENTE UN MEDIO CON ALTO CONTENIDO DE GLUCOSA, Y SE RECOGEN DICHOS ANTICUERPOS MONOCLONALES DE DICHO MEDIO DE CULTIVO. EL INVENTO ES ESPECIALMENTE UTIL EN RELACION CON INFECCIONES CAUSADAS POR BACTERIAS GRAM-NEGATIVAS.
ES8803336A 1986-04-24 1988-11-02 Procedimiento de obtencion de anticuerpos monoclonales para bacterias gram-negativas. Expired ES2009366A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/855,878 US4918163A (en) 1985-09-27 1986-04-24 Monoclonal antibodies specific for lipid-A determinants of gram negative bacteria

Publications (1)

Publication Number Publication Date
ES2009366A6 true ES2009366A6 (es) 1989-09-16

Family

ID=25322328

Family Applications (2)

Application Number Title Priority Date Filing Date
ES8803336A Expired ES2009366A6 (es) 1986-04-24 1988-11-02 Procedimiento de obtencion de anticuerpos monoclonales para bacterias gram-negativas.
ES8803335A Expired ES2009365A6 (es) 1986-04-24 1988-11-02 Procedimiento de otencion de anticuerpos monoclonales para bacterias gram-negativas.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES8803335A Expired ES2009365A6 (es) 1986-04-24 1988-11-02 Procedimiento de otencion de anticuerpos monoclonales para bacterias gram-negativas.

Country Status (2)

Country Link
US (1) US5698198A (es)
ES (2) ES2009366A6 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5959087A (en) * 1989-08-07 1999-09-28 Peptide Technology, Ltd. Tumour necrosis factor binding ligands
US6790661B1 (en) * 1999-07-16 2004-09-14 Verax Biomedical, Inc. System for detecting bacteria in blood, blood products, and fluids of tissues
US7132101B2 (en) * 2002-02-27 2006-11-07 Duquesne University Of The Holy Ghost Compositions and methods for eliciting an immune response to gram-negative bacterial infections

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4647447A (en) * 1981-07-24 1987-03-03 Schering Aktiengesellschaft Diagnostic media
US4443549A (en) * 1981-10-19 1984-04-17 Molecular Genetics, Inc. Production of monoclonal antibodies against bacterial adhesins
US4428931A (en) * 1982-03-15 1984-01-31 Merck & Co., Inc. Bacterial toxoids and gram-negative immune globulin therefrom
US4464465A (en) * 1982-04-05 1984-08-07 Genetic Systems Corporation Cell-driven viral transfer in eukaryotes
FI69639C (fi) * 1982-07-02 1986-03-10 Orion Yhtymae Oy Preparat foer anvaendning vid klamydia-diagnostik
JPS5929622A (ja) * 1982-08-10 1984-02-16 Meiji Seika Kaisha Ltd モノクロ−ナル抗体、その製造法およびその用途
US4689299A (en) * 1982-09-30 1987-08-25 University Of Rochester Human monoclonal antibodies against bacterial toxins
US4525453A (en) * 1982-10-26 1985-06-25 Eastman Kodak Company Process for rapidly differentiating between gram-negative and gram-positive microorganisms
US4574116A (en) * 1983-01-13 1986-03-04 The Board Of Trustees Of The Leland Stanford Jr. University Methods and cell lines for immortalization and monoclonal antibody production by antigen-stimulated B-lymphocytes
US5057598A (en) * 1983-05-06 1991-10-15 Centocor, Inc. Monoclonal antibodies reactive with endotoxin core
DE3484773D1 (de) * 1983-05-06 1991-08-08 Velos Group Mit endotoxinkern reaktionsfaehige monoklonale antikoerper.
US4587121A (en) * 1983-06-14 1986-05-06 Miles Laboratories, Inc. High titer Pseudomonas immune serum globulin
US5179018A (en) * 1983-10-14 1993-01-12 Centocor, Inc. Mamalian monoclonal antibodies against endotoxin of gram-negative bacteria
US4617264A (en) * 1983-11-04 1986-10-14 Syntex (U.S.A.) Inc. Pretreatment method and composition
US4683196A (en) * 1983-12-12 1987-07-28 Meru, Inc. Method and materials for the identification of lipopolysaccharide producing microorganisms
US4834975A (en) * 1984-05-25 1989-05-30 Genetics Corporation Human monoclonal antibodies to serotypic lipopolysaccharide determinants on gram-negative bacteria and their production
FI853395A7 (fi) * 1984-09-05 1986-03-06 Cetus Corp Monoklonaaliset vasta-aineet, jotka salpaavat gram-negatiivista bakteeriendotoksiinia.
JP2691708B2 (ja) * 1984-09-26 1997-12-17 住友製薬株式会社 ヒトモノクローナル抗体およびその製法
JPS61130300A (ja) * 1984-11-27 1986-06-18 ザ　ボ−ド　オブ　トラステイ−ズ　オブ　ザ　レランド　スタンフオ−ド　ジユニア　ユニバ−シテイ ヒトモノクロ−ナル抗体
AU597877B2 (en) * 1984-12-26 1990-06-14 Teijin Limited Anti-pseudomonas aeruginosa human monoclonal antibody
USH1198H (en) * 1985-04-26 1993-06-01 Cetus Corporation Pseudomonas aeruginosa type-specific human monoclonal antibodies, their preparation and use

Also Published As

Publication number Publication date
ES2009365A6 (es) 1989-09-16
US5698198A (en) 1997-12-16

Similar Documents

Publication Publication Date Title
IE862546L (en) Monoclonal antibodies binding dteterminants on gram negative¹bacteria
Isogai et al. Specific inhibition of adherence of an oral strain of Bacteroides gingivalis 381 to epithelial cells by monoclonal antibodies against the bacterial fimbriae
FI86377B (fi) Foerfarande foer framstaellning av terapeutiskt aktiva humana monoklonala antikroppar eller deras bindande fragment.
IE842625L (en) Monoclonal antibodies against endotoxin
US5641638A (en) Monoclonal antibodies against Mycoplasma pneumoniae, hybridomas producing these, methods for the preparation thereof, and the use thereof
US4607009A (en) Lewis blood group phenotype assay
Gustafsson et al. Monoclonal antibodies against group-and type-specific lipopolysaccharide antigens of Vibrio cholerae O: 1
Hamilton et al. Evidence that the M antigen of Histoplasma capsulatum var. capsulatum is a catalase which exhibits cross-reactivity with other dimorphic fungi
CA2656756C (en) Toxin detection method
AU628019B2 (en) A genus-specific listeria antigen identified by monoclonal antibodies
ES2009365A6 (es) Procedimiento de otencion de anticuerpos monoclonales para bacterias gram-negativas.
Blazek et al. Fast and simple procedure for the detection of cell culture mycoplasmas using a single monoclonal antibody
AU5309386A (en) Anti-pseudomonas aeruginosa human monoclonal antibody
Edwin et al. Production of monoclonal antibodies to staphylococcal enterotoxin A
Furuya et al. Use of monoclonal antibodies against Rickettsia tsutsugamushi Kawasaki for serodiagnosis by enzyme-linked immunosorbent assay
Lind et al. Production and characterization of KDO-specific monoclonal antibodies recognizing lipopolysaccharides from heptoseless mutants of Salmonella
Rodriguez Barbosa et al. Evidence obtained with monoclonal antibodies that O antigen is the major antigen responsible for the cross-reactivities between serotypes 4 and 7 of Actinobacillus (Haemophilus) pleuropneumoniae
US5162223A (en) Hybridomas and resulting monoclonal antibodies directed against antigens of Bordetella pertussis
Magee et al. Monoclonal antibodies specific for Corynebacterium sepedonicum, the causative agent of potato ring rot
Ueyama et al. Identification of common lipooligosaccharide types in isolates from patients with otitis media by monoclonal antibodies against nontypeable Haemophilus influenzae 9274
Honda et al. Production of monoclonal antibodies against a hemagglutinin/protease of Vibrio cholerae non-01
Honda et al. Production of monoclonal antibody against a hemolysin (Vp-TRH) produced by Vibrio parahaemolyticus
Miyazaki et al. Production of monoclonal antibodies against Legionella pneumophila serogroup 1
Kudo et al. Isolation the characterization of monoclonal antibodies against pili of Corynebacterium renale and Corynebacterium pilosum
Jensen et al. A serological study with monoclonal antibodies to an antigen common to a wide range of bacteria