ES2009604A6 - Procedimiento de obtencion de acetil-salicilato de 7-(2-dietilaminoetil)-teofilina. - Google Patents
Procedimiento de obtencion de acetil-salicilato de 7-(2-dietilaminoetil)-teofilina.Info
- Publication number
- ES2009604A6 ES2009604A6 ES8801377A ES8801377A ES2009604A6 ES 2009604 A6 ES2009604 A6 ES 2009604A6 ES 8801377 A ES8801377 A ES 8801377A ES 8801377 A ES8801377 A ES 8801377A ES 2009604 A6 ES2009604 A6 ES 2009604A6
- Authority
- ES
- Spain
- Prior art keywords
- theophylline
- diethylaminoethyl
- preparation
- acetyl salicylate
- product
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 4
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 title abstract 2
- 229940068372 acetyl salicylate Drugs 0.000 title abstract 2
- AWKLBIOQCIORSB-UHFFFAOYSA-N etamiphylline Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2CCN(CC)CC AWKLBIOQCIORSB-UHFFFAOYSA-N 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 2
- 239000005909 Kieselgur Substances 0.000 abstract 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000003146 anticoagulant agent Substances 0.000 abstract 1
- 229960004676 antithrombotic agent Drugs 0.000 abstract 1
- 238000001816 cooling Methods 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000376 reactant Substances 0.000 abstract 1
- 238000002604 ultrasonography Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PROCEDIMIENTO DE OBTENCION DE ACETILSALICILATO DE 7-(2-DIETILAMINOETIL)-TEOFILINA QUE COMPRENDE UN FILTRADO PREVIO DE UNA SOLUCION CON LOS REACTANTES EN CAPA DE TIERRA DE INFUSORIOS Y CARBON ACTIVO, ENFRIADO Y APLICACION DE UNA FUENTE DE ULTRASONIDO DE ALTA FRECUENCIA. EL PROCEDIMIENTO PROPORCIONA PRODUCTOS DE ALTO GRADO DE PUREZA UTILES PARA LA MANUFACTURACION DE AGENTES ANTIAGREGANTES Y ANTITROMBOTICOS.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES8801377A ES2009604A6 (es) | 1988-05-05 | 1988-05-05 | Procedimiento de obtencion de acetil-salicilato de 7-(2-dietilaminoetil)-teofilina. |
| US07/316,872 US4908111A (en) | 1988-05-05 | 1989-02-28 | Process for the preparation of 7-(2-diethylaminoethyl)-theophylline acetyl salicylate and use thereof |
| FR898903516A FR2631030B1 (fr) | 1988-05-05 | 1989-03-17 | Procede d'obtention d'acetyl-salicylate de 7-(2-diethylamino-ethyl)-theophylline et son application a la preparation d'agents anti-agglutinants et anti-thrombotiques |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES8801377A ES2009604A6 (es) | 1988-05-05 | 1988-05-05 | Procedimiento de obtencion de acetil-salicilato de 7-(2-dietilaminoetil)-teofilina. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2009604A6 true ES2009604A6 (es) | 1989-10-01 |
Family
ID=8256153
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES8801377A Expired ES2009604A6 (es) | 1988-05-05 | 1988-05-05 | Procedimiento de obtencion de acetil-salicilato de 7-(2-dietilaminoetil)-teofilina. |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US4908111A (es) |
| ES (1) | ES2009604A6 (es) |
| FR (1) | FR2631030B1 (es) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES501162A0 (es) * | 1981-04-07 | 1982-02-01 | Coma Julia Concepcion | Procedimiento para la obtencion de acetilsalicilato de 7-(2-dietilaminoetil)-teofilina |
-
1988
- 1988-05-05 ES ES8801377A patent/ES2009604A6/es not_active Expired
-
1989
- 1989-02-28 US US07/316,872 patent/US4908111A/en not_active Expired - Fee Related
- 1989-03-17 FR FR898903516A patent/FR2631030B1/fr not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| FR2631030B1 (fr) | 1992-02-28 |
| US4908111A (en) | 1990-03-13 |
| FR2631030A1 (fr) | 1989-11-10 |
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| ES2009604A6 (es) | Procedimiento de obtencion de acetil-salicilato de 7-(2-dietilaminoetil)-teofilina. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19990201 |