ES2015047B3 - Nuevos derivados de 18-fenilestrano. - Google Patents

Nuevos derivados de 18-fenilestrano.

Info

Publication number
ES2015047B3
ES2015047B3 ES87201258T ES87201258T ES2015047B3 ES 2015047 B3 ES2015047 B3 ES 2015047B3 ES 87201258 T ES87201258 T ES 87201258T ES 87201258 T ES87201258 T ES 87201258T ES 2015047 B3 ES2015047 B3 ES 2015047B3
Authority
ES
Spain
Prior art keywords
fenilestrano
new derivatives
derivatives
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87201258T
Other languages
English (en)
Inventor
Jongh Hendrik Paul De
Den Heuvel Martinus Johannes Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo NV
Original Assignee
Akzo NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo NV filed Critical Akzo NV
Application granted granted Critical
Publication of ES2015047B3 publication Critical patent/ES2015047B3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0044Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an estrane or gonane skeleton, including 18-substituted derivatives and derivatives where position 17-beta is substituted by a carbon atom not directly bonded to another carbon atom and not being part of an amide group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES87201258T 1986-07-23 1987-07-02 Nuevos derivados de 18-fenilestrano. Expired - Lifetime ES2015047B3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8601903 1986-07-23

Publications (1)

Publication Number Publication Date
ES2015047B3 true ES2015047B3 (es) 1990-08-01

Family

ID=19848343

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87201258T Expired - Lifetime ES2015047B3 (es) 1986-07-23 1987-07-02 Nuevos derivados de 18-fenilestrano.

Country Status (15)

Country Link
US (1) US4808710A (es)
EP (1) EP0254341B1 (es)
JP (1) JPS6335595A (es)
KR (1) KR880001693A (es)
CN (1) CN87106126A (es)
AU (1) AU598836B2 (es)
CA (1) CA1284318C (es)
DE (1) DE3761308D1 (es)
DK (1) DK383887A (es)
ES (1) ES2015047B3 (es)
FI (1) FI84274C (es)
GR (1) GR3001005T3 (es)
NZ (1) NZ221019A (es)
PT (1) PT85395B (es)
ZA (1) ZA874863B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4992485A (en) * 1988-10-11 1991-02-12 The Dow Chemical Company Microporous peek membranes and the preparation thereof
DE3921059A1 (de) * 1989-06-23 1991-01-10 Schering Ag 11(beta)-aryl-4-estrene, verfahren zu ihrer herstellung sowie deren verwendung als arzneimittel
ZA929315B (en) * 1991-12-20 1993-05-24 Akzo Nv 17-spirofuran-3'-ylidene steroids.
DE69702450T2 (de) * 1996-05-01 2001-03-08 The Government Of The United States Of America As Represented By The Secretary Of National Institute Of Health, Office Of Technology Transfer 21-substituierte progesteron derivate als antigestagene
US6900193B1 (en) * 1996-05-01 2005-05-31 The United States Of America As Represented By The Department Of Health And Human Services Structural modification of 19-norprogesterone I: 17-α-substituted-11-β-substituted-4-aryl and 21-substituted 19-norpregnadienedione as new antiprogestational agents
AU2004217988C1 (en) * 2003-02-28 2010-06-03 Southwest Foundation For Biomedical Research Method for preparing 17 alpha-acetoxy-11beta-(4-N,N-dimethylaminophenyl)-19-norpregna-4,9-diene-3,20-dione, intermediates thereof, and methods for the preparation of such intermediates
CA2551737C (en) * 2004-01-07 2009-11-10 Endorecherche, Inc. Helix 12 directed steroidal pharmaceutical products
US7709516B2 (en) 2005-06-17 2010-05-04 Endorecherche, Inc. Helix 12 directed non-steroidal antiandrogens
PL2576582T3 (pl) 2010-05-26 2020-06-29 Corcept Therapeutics, Inc. Leczenie dystrofii mięśniowej
WO2016140867A1 (en) 2015-03-02 2016-09-09 Corcept Therapeutics, Inc. Use of glucocorticoid receptor antagonist and somatostatin analogues to treat acth-secreting tumors
US10610534B2 (en) 2015-03-30 2020-04-07 Corcept Therapeutics, Inc. Use of glucocorticoid receptor antagonists in combination with glucocorticoids to treat adrenal insufficiency
KR20180052120A (ko) 2015-08-13 2018-05-17 코어셉트 쎄라퓨틱스, 잉크. Acth-의존성 쿠싱 증후군을 감별 진단하는 방법
KR102197526B1 (ko) 2016-01-19 2020-12-31 코어셉트 쎄라퓨틱스 인코포레이티드 이소성 쿠싱 증후군의 감별 진단
SG11201908790PA (en) 2017-03-31 2019-10-30 Corcept Therapeutics Inc Glucocorticoid receptor modulators to treat cervical cancer
MX393313B (es) 2017-06-20 2025-03-24 Corcept Therapeutics Inc Metodos de tratamiento de tumores neuroepiteliales usando moduladores selectivos del receptor de glucocorticoide.
AU2020239920A1 (en) 2019-03-18 2021-11-04 Arnold L. Newman Method of improving insulin sensitivity
JP2024500748A (ja) 2020-12-18 2024-01-10 インスティル バイオ (ユーケイ) リミテッド 腫瘍浸潤リンパ球の処理

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1255345A (en) * 1916-05-20 1918-02-05 Arthur L Shaw Conveyer.
US3100204A (en) * 1960-04-20 1963-08-06 Merck & Co Inc Haloethisterone compounds
US3074978A (en) * 1961-01-11 1963-01-22 Roussel Uclaf Process for the preparation of 13beta-n-propyl-delta4-gonene-17beta-ol-3-one and the intermediates in the preparation thereof
US3177205A (en) * 1963-03-01 1965-04-06 Syntex Corp 19-lower-alkyl-10alpha-derivatives of cortical hormones
JPS4118820Y1 (es) * 1965-09-22 1966-09-02
BE697838A (es) * 1966-11-11 1967-10-02
US3725439A (en) * 1971-01-07 1973-04-03 Merck & Co Inc 13-carbocyclic-3-keto-4-gonenes
US4167517A (en) * 1976-06-14 1979-09-11 Veb Jenapharm Gona-4,9(10)-dienes and process of producing the same
ZA8231B (en) * 1981-01-09 1982-11-24 Roussel Uclaf New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained

Also Published As

Publication number Publication date
KR880001693A (ko) 1988-04-26
DK383887A (da) 1988-01-24
EP0254341A1 (en) 1988-01-27
ZA874863B (en) 1988-01-13
GR3001005T3 (en) 1991-12-30
CA1284318C (en) 1991-05-21
FI873193A0 (fi) 1987-07-20
NZ221019A (en) 1989-12-21
PT85395B (pt) 1990-04-30
DE3761308D1 (de) 1990-02-08
US4808710A (en) 1989-02-28
AU7596987A (en) 1988-01-28
DK383887D0 (da) 1987-07-22
AU598836B2 (en) 1990-07-05
CN87106126A (zh) 1988-05-11
FI84274C (fi) 1991-11-11
FI873193A7 (fi) 1988-01-24
FI84274B (fi) 1991-07-31
EP0254341B1 (en) 1990-01-03
JPS6335595A (ja) 1988-02-16
PT85395A (en) 1987-08-01

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