ES2018389A6 - Procedmiento para la preparacion de granulos microencapsulados de amoxicilina. - Google Patents

Procedmiento para la preparacion de granulos microencapsulados de amoxicilina.

Info

Publication number
ES2018389A6
ES2018389A6 ES8902945A ES8902945A ES2018389A6 ES 2018389 A6 ES2018389 A6 ES 2018389A6 ES 8902945 A ES8902945 A ES 8902945A ES 8902945 A ES8902945 A ES 8902945A ES 2018389 A6 ES2018389 A6 ES 2018389A6
Authority
ES
Spain
Prior art keywords
granules
amoxicillin
microencapsulated granules
amoxicillin microencapsulated
disclosed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES8902945A
Other languages
English (en)
Inventor
Robert P Giannini
Daniel A Bashour
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HiMedics Inc
Original Assignee
HiMedics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HiMedics Inc filed Critical HiMedics Inc
Publication of ES2018389A6 publication Critical patent/ES2018389A6/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE GRANULOS MICROENCAPSULADOS DE AMOXICILINA QUE TIENEN DENSIDADES DE ACTIVIDAD SUPERIORES A 0,2 G/ML APROXIMADAMENTE Y UN DIAMETRO DESUSUALMENTE PEQUEÑO, INFERIOR A 1.000 MICRAS APROXIMADAMENTE. EL PROCEDIMIENTO COMPRENDE APLICAR UNA COMPOSICION DE REVESTIMIENTO ACTIVO A UN NUCLEO INERTE PARA FORMAR ASI UN NUCLEO ACTIVO, COMPRENDIENDO LA COMPOSICION DE REVESTIMIENTO ACTIVO, APROXIMADAMENTE, 29 A 33% EN PESO DE AMOXICILINA, 2 A 6% EN PESO DE UN AGLUTINANTE Y UN DISOLVENTE. OPCIONALMENTE, SE PUEDE APLICAR UN REVESTIMIENTO ENMASCARANTE DEL SABOR Y LOS GRANULOS OBTENIDOS SON PARTICULARMENTE UTILES PARA UTILIZARSE EN DISPENSADORES MANUALES DE MATERIALES FLUIBLES.
ES8902945A 1988-08-25 1989-08-25 Procedmiento para la preparacion de granulos microencapsulados de amoxicilina. Expired - Lifetime ES2018389A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/236,375 US4925674A (en) 1988-08-25 1988-08-25 Amoxicillin microencapsulated granules

Publications (1)

Publication Number Publication Date
ES2018389A6 true ES2018389A6 (es) 1991-04-01

Family

ID=22889231

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8902945A Expired - Lifetime ES2018389A6 (es) 1988-08-25 1989-08-25 Procedmiento para la preparacion de granulos microencapsulados de amoxicilina.

Country Status (4)

Country Link
US (1) US4925674A (es)
AU (1) AU4036989A (es)
ES (1) ES2018389A6 (es)
WO (1) WO1990001932A1 (es)

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US5152995A (en) * 1986-12-18 1992-10-06 Syntex (U.S.A.) Inc. Stable antibiotic ester feed compositions
US4966770A (en) * 1989-07-26 1990-10-30 Himedics, Inc. Prednisone microencapsulated granules
ZA937382B (en) * 1992-10-06 1994-04-29 Warner Lambert Co Novel composition for peroral therapy of cognitionimpairment and a process therefor
KR0168715B1 (ko) * 1992-11-30 1999-01-15 밋첼 아이. 커시너 맛을 차단하는 약제학적 조성물
DE69524214T3 (de) * 1994-05-06 2008-05-15 Pfizer Inc. Azithromycin enthaltende arzneiverabreichungsformen mit gesteuerter wirkstoffabgabe
GB9416600D0 (en) * 1994-08-17 1994-10-12 Smithkline Beecham Plc Pharmaceutical formulation
FR2759293B1 (fr) * 1997-02-11 1999-04-30 Ethypharm Lab Prod Ethiques Microgranules contenant du cisplatine, procede de fabrication, preparation pharmaceutique et utilisation en polychimiotherapie ou en association avec une radiotherapie
US6022554A (en) * 1997-12-15 2000-02-08 American Home Products Corporation Polymeric microporous film coated subcutaneous implant
US6238697B1 (en) * 1998-12-21 2001-05-29 Pharmalogix, Inc. Methods and formulations for making bupropion hydrochloride tablets using direct compression
FR2796840B1 (fr) * 1999-07-26 2003-06-20 Ethypharm Lab Prod Ethiques Comprimes faiblement doses et procede de preparation
US20020028240A1 (en) * 2000-04-17 2002-03-07 Toyohiro Sawada Timed-release compression-coated solid composition for oral administration
US7790905B2 (en) * 2002-02-15 2010-09-07 Mcneil-Ppc, Inc. Pharmaceutical propylene glycol solvate compositions
US20100311701A1 (en) * 2002-02-15 2010-12-09 Transform Pharmaceuticals, Inc Pharmaceutical Co-Crystal Compositions
US7927613B2 (en) * 2002-02-15 2011-04-19 University Of South Florida Pharmaceutical co-crystal compositions
IL163846A0 (en) * 2002-03-01 2005-12-18 Univ South Florida Multiple-component solid phases containing at least one active pharmaceutical ingredient
IL165383A0 (en) * 2002-06-21 2006-01-15 Transform Pharmaceuticals Inc Pharmaceutical compositions with improved dissolution
US20040208936A1 (en) * 2002-07-22 2004-10-21 Roland Chorin Novel compositions
US8183290B2 (en) * 2002-12-30 2012-05-22 Mcneil-Ppc, Inc. Pharmaceutically acceptable propylene glycol solvate of naproxen
US20060073205A1 (en) * 2004-10-04 2006-04-06 Kotoe Ohta Controlled release granules comprising porous silica core
US8343546B2 (en) * 2005-09-13 2013-01-01 Coating Place, Inc. Ion exchange resin treated to control swelling
EP2699094A4 (en) * 2011-04-22 2014-12-17 Merck Sharp & Dohme TASTE-MASKED FORMULATIONS BY RALTEGRAVIR
CN112156082A (zh) * 2020-11-16 2021-01-01 海南海力制药有限公司 一种阿莫西林胶囊制备方法和阿莫西林胶囊
CN113133985A (zh) * 2021-04-16 2021-07-20 海南通用三洋药业有限公司 一种阿莫西林胶囊制备方法
CN113933237B (zh) * 2021-10-20 2023-10-13 山西信谊通制药有限公司 一种阿莫西林胶囊检测装置

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2738303A (en) * 1952-07-18 1956-03-13 Smith Kline French Lab Sympathomimetic preparation
GB1423694A (en) * 1973-07-10 1976-02-04 Beecham Group Ltd Pharmaceutical compositions
DE2336218C3 (de) * 1973-07-17 1985-11-14 Byk Gulden Lomberg Chemische Fabrik Gmbh, 7750 Konstanz Orale Arzneiform
JPS5132719A (en) * 1974-09-13 1976-03-19 Yoshinobu Nakai Iyakuhinnoshorihoho
SE418247B (sv) * 1975-11-17 1981-05-18 Haessle Ab Sett att framstella kroppar med reglerad frigoring av en aktiv komponent
US4349531A (en) * 1975-12-15 1982-09-14 Hoffmann-La Roche Inc. Novel dosage form
GB1561301A (en) * 1976-01-02 1980-02-20 Beecham Group Ltd Orally administrable pharmaceutical composition
GB1576376A (en) * 1977-03-30 1980-10-08 Benzon As Alfred Multiple-unit drug dose
GB1561204A (en) * 1977-06-01 1980-02-13 Ici Ltd Sustained release pharmaceutical composition
DE2965732D1 (en) * 1978-12-08 1983-07-28 Beecham Group Plc Pharmaceutical composition comprising a water soluble salt of amoxycillin and polyvinylpyrrolidone, and a vial containing a unit dose of said composition
SE7813246L (sv) * 1978-12-22 1980-06-23 Haessle Ab Fast farmaceutisk beredning innehallande kroppar med flera ytskikt
JPS55153715A (en) * 1979-05-18 1980-11-29 Nikken Kagaku Kk Prolonged granule of theophylline
WO1983000284A1 (en) * 1981-07-15 1983-02-03 Key Pharma Sustained release theophylline
US4587118A (en) * 1981-07-15 1986-05-06 Key Pharmaceuticals, Inc. Dry sustained release theophylline oral formulation
DK150008C (da) * 1981-11-20 1987-05-25 Benzon As Alfred Fremgangsmaade til fremstilling af et farmaceutisk oralt polydepotpraeparat
US4758437A (en) * 1981-12-23 1988-07-19 Yamanouchi Pharmaceutical Co., Ltd. Composition for long acting nicardipine preparation and process of producing the composition
US4508702A (en) * 1982-06-14 1985-04-02 Key Pharmaceuticals, Inc. Sustained release aspirin
DE3271662D1 (en) * 1982-08-26 1986-07-17 Sulzer Ag Loom with oiling device for weft-inserting means
US4525339A (en) * 1982-10-15 1985-06-25 Hoffmann-La Roche Inc. Enteric coated oral dosage form

Also Published As

Publication number Publication date
AU4036989A (en) 1990-03-23
US4925674A (en) 1990-05-15
WO1990001932A1 (en) 1990-03-08

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Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2009-08-25