ES2018407A6 - Process for obtaining 1-aryloxy-3-nitroamino-2-propanols - Google Patents
Process for obtaining 1-aryloxy-3-nitroamino-2-propanolsInfo
- Publication number
- ES2018407A6 ES2018407A6 ES8903562A ES8903562A ES2018407A6 ES 2018407 A6 ES2018407 A6 ES 2018407A6 ES 8903562 A ES8903562 A ES 8903562A ES 8903562 A ES8903562 A ES 8903562A ES 2018407 A6 ES2018407 A6 ES 2018407A6
- Authority
- ES
- Spain
- Prior art keywords
- aryloxy
- nitroamino
- propanols
- obtaining
- straight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000000034 method Methods 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- HOPRXXXSABQWAV-UHFFFAOYSA-N anhydrous collidine Natural products CC1=CC=NC(C)=C1C HOPRXXXSABQWAV-UHFFFAOYSA-N 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 230000005792 cardiovascular activity Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- UTBIMNXEDGNJFE-UHFFFAOYSA-N collidine Natural products CC1=CC=C(C)C(C)=N1 UTBIMNXEDGNJFE-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
- GFYHSKONPJXCDE-UHFFFAOYSA-N sym-collidine Natural products CC1=CN=C(C)C(C)=C1 GFYHSKONPJXCDE-UHFFFAOYSA-N 0.000 abstract 1
- -1 thionyl nitrate chloride Chemical compound 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Process for obtaining 1-aryloxy-3-nitroamino-2-propanols of formula I where: Ar represents a phenyl or naphthyl radical R1 and R2, which may be the same or different, can occupy any substitution position relative to the aromatic nucleus and represent hydrogen or a straight or branched alkyl chain of 1 to 4 carbon atoms and R3 represents a straight or branched alkyl chain of 1 to 4 carbon atoms, based on the reaction of a 1-aryloxy-3- amino-2-propanol of formula < IMAGE > in which Ar, R1, R2 and R3 have the meanings indicated above, with a member of the group comprising thionyl nitrate chloride and n-nitro collidine tetrafluorate. These compounds are of pharmacological use, particularly for cardiovascular activity.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES8903562A ES2018407A6 (en) | 1989-10-23 | 1989-10-23 | Process for obtaining 1-aryloxy-3-nitroamino-2-propanols |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES8903562A ES2018407A6 (en) | 1989-10-23 | 1989-10-23 | Process for obtaining 1-aryloxy-3-nitroamino-2-propanols |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2018407A6 true ES2018407A6 (en) | 1991-04-01 |
Family
ID=8264451
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES8903562A Expired - Fee Related ES2018407A6 (en) | 1989-10-23 | 1989-10-23 | Process for obtaining 1-aryloxy-3-nitroamino-2-propanols |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES2018407A6 (en) |
-
1989
- 1989-10-23 ES ES8903562A patent/ES2018407A6/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19981001 |