ES2018903A6 - Un metodo de diagnosticar la presencia de una infeccion virica cronica, como el sindrome de fatiga cronica (cfs) - Google Patents
Un metodo de diagnosticar la presencia de una infeccion virica cronica, como el sindrome de fatiga cronica (cfs)Info
- Publication number
- ES2018903A6 ES2018903A6 ES8902387A ES8902387A ES2018903A6 ES 2018903 A6 ES2018903 A6 ES 2018903A6 ES 8902387 A ES8902387 A ES 8902387A ES 8902387 A ES8902387 A ES 8902387A ES 2018903 A6 ES2018903 A6 ES 2018903A6
- Authority
- ES
- Spain
- Prior art keywords
- chronic fatigue
- fatigue syndrome
- diagnosing
- treating chronic
- levels
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 206010008874 Chronic Fatigue Syndrome Diseases 0.000 title abstract 3
- 208000029766 myalgic encephalomeyelitis/chronic fatigue syndrome Diseases 0.000 title abstract 3
- 108091032973 (ribonucleotides)n+m Proteins 0.000 abstract 2
- 102000040650 (ribonucleotides)n+m Human genes 0.000 abstract 2
- 108091034117 Oligonucleotide Proteins 0.000 abstract 1
- 230000002093 peripheral effect Effects 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
METODO DE DIAGNOSTICAR LA PRESENCIA DE UNA INFECCION VIRICA CRONICA, COMO EL SINDROME DE FATIGA CRONICA (CFS). CONSISTE EN DETERMINA LA VIA DE 2''-5'' A/RNASA L, INCLUYENDO LA MEDIDA DE LOS NIVELES DE OLIGONUCLEOTIDOS 2''-5'' A LOS LEUCOCITOS DE LA CIRCULACION SANGUINEA PERIFERICA DEL PACIENTE, Y COMPARAR ESTOS RESULTADOS CON LOS DE INDIVIDUOS SANOS. LA UTILIDAD DEL INVENTO RADICA EN QUE LOS ARN BICATENARIOS, PARTICULARMENTE LOS ARN BICATENARIOS DESAPAREADOS, CUANDO SE ADMINISTRAN EN CANTIDADES APROPIADAS, AUMENTAN EL 2''-5'' A Y NORMALIZAN LA VIA ANTIVIRICA EN PACIENTES CON SINDROME DE FATIGA CRONICA, Y MEJORAN LOS SINTOMAS CLINICOS.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200301485A ES2223273A6 (es) | 1988-07-07 | 2003-06-24 | Mejora de la patente 8902387/0 para un metodo de diagnosticar la presencia de una infeccion virica cronica, como el sindrome de fatiga cronica (cfs). |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22076588A | 1988-07-07 | 1988-07-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2018903A6 true ES2018903A6 (es) | 1991-05-16 |
Family
ID=22824871
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES89304188T Expired - Lifetime ES2066847T3 (es) | 1988-07-07 | 1989-04-26 | Diagnostico y tratamiento del sindrome de fatiga cronica. |
| ES8902387A Expired - Fee Related ES2018903A6 (es) | 1988-07-07 | 1989-07-06 | Un metodo de diagnosticar la presencia de una infeccion virica cronica, como el sindrome de fatiga cronica (cfs) |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES89304188T Expired - Lifetime ES2066847T3 (es) | 1988-07-07 | 1989-04-26 | Diagnostico y tratamiento del sindrome de fatiga cronica. |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0350151B1 (es) |
| CN (1) | CN1056747C (es) |
| AT (1) | ATE103493T1 (es) |
| AU (2) | AU3781189A (es) |
| CA (1) | CA1336685C (es) |
| DE (1) | DE68914201T2 (es) |
| DK (1) | DK332289A (es) |
| ES (2) | ES2066847T3 (es) |
| IE (1) | IE63927B1 (es) |
| IL (1) | IL90875A (es) |
| NZ (1) | NZ229849A (es) |
| PT (1) | PT91094B (es) |
| ZA (1) | ZA895143B (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0495831B1 (en) * | 1989-10-16 | 1997-01-15 | Hem Pharmaceuticals Corp. | Diagnosis and treatment of neuro-cognitive disorders associated with systemic immunological malfunction |
| GB9108085D0 (en) * | 1991-04-16 | 1991-06-05 | Scras | Complexes of polyadenylic acid with polyuridylic acid |
| US5776690A (en) * | 1996-10-07 | 1998-07-07 | Vojdani; Aristo | Detection of chronic fatigue syndrome by decreased levels of RNase L inhibitor mRNA |
| US6506559B1 (en) | 1997-12-23 | 2003-01-14 | Carnegie Institute Of Washington | Genetic inhibition by double-stranded RNA |
| AUPP249298A0 (en) | 1998-03-20 | 1998-04-23 | Ag-Gene Australia Limited | Synthetic genes and genetic constructs comprising same I |
| WO1999049029A1 (en) | 1998-03-20 | 1999-09-30 | Benitec Australia Ltd | Control of gene expression |
| EP2314700A1 (en) | 1999-01-28 | 2011-04-27 | Medical College of Georgia Research Institute, Inc | Composition and method for in vivo and in vitro attenuation of gene expression using double stranded RNA |
| US6423885B1 (en) | 1999-08-13 | 2002-07-23 | Commonwealth Scientific And Industrial Research Organization (Csiro) | Methods for obtaining modified phenotypes in plant cells |
| EP1229134A3 (en) | 2001-01-31 | 2004-01-28 | Nucleonics, Inc | Use of post-transcriptional gene silencing for identifying nucleic acid sequences that modulate the function of a cell |
| US20120004290A1 (en) * | 2009-03-13 | 2012-01-05 | David Strayer | Treating chronic fatigue syndrome and prolonged qt interval |
| EP3652542A1 (en) * | 2017-07-14 | 2020-05-20 | Protea Biopharma N.V. | Methods and means for diagnosing and/or treating a fatiguing illness |
| EP3893893A1 (en) * | 2018-12-13 | 2021-10-20 | Aim Immunotech Inc. | Methods for improving exercise tolerance in myalgic encephalomyelitis patients |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1326450C (en) * | 1985-08-26 | 1994-01-25 | William A. Carter | Modulation of aids virus-related events by double stranded rnas (dsrnas) |
| PH30882A (en) * | 1987-03-03 | 1997-12-23 | Hem Res Inc | Activated Rnase L as a maker for viral infections. |
| AU1820388A (en) * | 1987-07-17 | 1989-01-19 | Hem Research, Inc. | Double stranded rna correction of aberrant metabolic pathways associated with uncontrolled tumor cell and virus growth cycles |
| DE3853755T2 (de) * | 1987-09-04 | 1995-12-14 | Hem Pharma Corp | Diagnose von Mangelzuständen doppelsträngiger RNS. |
-
1989
- 1989-04-26 DE DE68914201T patent/DE68914201T2/de not_active Expired - Fee Related
- 1989-04-26 ES ES89304188T patent/ES2066847T3/es not_active Expired - Lifetime
- 1989-04-26 AT AT89304188T patent/ATE103493T1/de not_active IP Right Cessation
- 1989-04-26 EP EP89304188A patent/EP0350151B1/en not_active Expired - Lifetime
- 1989-06-30 CA CA000604511A patent/CA1336685C/en not_active Expired - Fee Related
- 1989-07-04 AU AU37811/89A patent/AU3781189A/en not_active Abandoned
- 1989-07-04 DK DK332289A patent/DK332289A/da not_active Application Discontinuation
- 1989-07-05 IL IL9087589A patent/IL90875A/en not_active IP Right Cessation
- 1989-07-06 ES ES8902387A patent/ES2018903A6/es not_active Expired - Fee Related
- 1989-07-06 IE IE218089A patent/IE63927B1/en not_active IP Right Cessation
- 1989-07-06 ZA ZA895143A patent/ZA895143B/xx unknown
- 1989-07-06 NZ NZ229849A patent/NZ229849A/en unknown
- 1989-07-07 PT PT91094A patent/PT91094B/pt not_active IP Right Cessation
- 1989-07-07 CN CN89106706A patent/CN1056747C/zh not_active Expired - Fee Related
-
1994
- 1994-08-02 AU AU68836/94A patent/AU684288B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| IL90875A (en) | 1994-04-12 |
| IL90875A0 (en) | 1990-02-09 |
| DK332289A (da) | 1990-01-08 |
| CN1056747C (zh) | 2000-09-27 |
| AU3781189A (en) | 1990-01-11 |
| IE63927B1 (en) | 1995-06-28 |
| ZA895143B (en) | 1991-04-24 |
| CN1039722A (zh) | 1990-02-21 |
| IE892180L (en) | 1990-01-07 |
| EP0350151A2 (en) | 1990-01-10 |
| ATE103493T1 (de) | 1994-04-15 |
| DE68914201T2 (de) | 1994-07-14 |
| PT91094A (pt) | 1990-02-08 |
| EP0350151A3 (en) | 1990-10-03 |
| CA1336685C (en) | 1995-08-15 |
| AU6883694A (en) | 1994-11-24 |
| EP0350151B1 (en) | 1994-03-30 |
| ES2066847T3 (es) | 1995-03-16 |
| AU684288B2 (en) | 1997-12-11 |
| DK332289D0 (da) | 1989-07-04 |
| NZ229849A (en) | 1997-07-27 |
| PT91094B (pt) | 1995-01-31 |
| DE68914201D1 (de) | 1994-05-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC1A | Transfer granted | ||
| FD1A | Patent lapsed |
Effective date: 20100315 |