ES2021904A6 - Procedimiento para preparar una composicion farmaceutica a base de un acido piperacinacarboxilico. - Google Patents

Procedimiento para preparar una composicion farmaceutica a base de un acido piperacinacarboxilico.

Info

Publication number
ES2021904A6
ES2021904A6 ES8903482A ES8903482A ES2021904A6 ES 2021904 A6 ES2021904 A6 ES 2021904A6 ES 8903482 A ES8903482 A ES 8903482A ES 8903482 A ES8903482 A ES 8903482A ES 2021904 A6 ES2021904 A6 ES 2021904A6
Authority
ES
Spain
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
acid
piperazinecarboxylic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES8903482A
Other languages
English (en)
Inventor
Bernhard Aebischer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES2021904A6 publication Critical patent/ES2021904A6/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C07F9/650952—Six-membered rings having the nitrogen atoms in the positions 1 and 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR UNA COMPOSICION FARMACEUTICA A BASE DE ACIDO PIPERACINACARBOXILICO. COMPRENDE MEZCLAR UN ACIDO [R-(E)]-4-(3-FOSFONO-2-PROPENIL)-2-PIPERACINACARBOXILICO DE FORMULA (I) O UN HIDRATO O UNA SAL DEL MISMO, CON UN VEHICULO O DILUYENTE FARMACEUTICAMENTE ACEPTABLE, TAL COMO PARA PRODUCIR UNA FORMA DE UNIDAD DE DOSIFICACION QUE CONTIENE APROXIMADAMENTE DE 0,25 A 0,400 MG DEL COMPUESTO DE FORMULA (I). LA COMPOSICION ASI OBTENIDA POSEE ACTIVIDAD SOBRE EL SISTEMA NERVIOSO CENTRAL.
ES8903482A 1987-02-18 1989-10-16 Procedimiento para preparar una composicion farmaceutica a base de un acido piperacinacarboxilico. Expired - Lifetime ES2021904A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878703749A GB8703749D0 (en) 1987-02-18 1987-02-18 Piperazinecarboxylic acid

Publications (1)

Publication Number Publication Date
ES2021904A6 true ES2021904A6 (es) 1991-11-16

Family

ID=10612501

Family Applications (2)

Application Number Title Priority Date Filing Date
ES888800466A Expired - Lifetime ES2011319A6 (es) 1987-02-18 1988-02-18 Procedimiento para preparar acidos piperacinacarboxilicos.
ES8903482A Expired - Lifetime ES2021904A6 (es) 1987-02-18 1989-10-16 Procedimiento para preparar una composicion farmaceutica a base de un acido piperacinacarboxilico.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES888800466A Expired - Lifetime ES2011319A6 (es) 1987-02-18 1988-02-18 Procedimiento para preparar acidos piperacinacarboxilicos.

Country Status (28)

Country Link
JP (1) JPH0723387B2 (es)
KR (1) KR960015190B1 (es)
AT (1) AT391320B (es)
AU (1) AU613009B2 (es)
BE (1) BE1002427A3 (es)
CA (1) CA1327799C (es)
CH (1) CH675125A5 (es)
CY (1) CY1739A (es)
DE (1) DE3804936C2 (es)
DK (1) DK168441B1 (es)
ES (2) ES2011319A6 (es)
FI (1) FI86733C (es)
FR (1) FR2610932B1 (es)
GB (2) GB8703749D0 (es)
GR (1) GR1002471B (es)
HK (1) HK142093A (es)
HU (2) HU199858B (es)
IE (1) IE59098B1 (es)
IL (1) IL85436A0 (es)
IT (1) IT1219447B (es)
LU (1) LU87129A1 (es)
MY (1) MY103206A (es)
NL (1) NL8800412A (es)
NZ (1) NZ223529A (es)
PH (1) PH25512A (es)
PT (1) PT86776B (es)
SE (1) SE467256B (es)
ZA (1) ZA881146B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU202111B (en) * 1988-03-11 1991-02-28 Sandoz Ag Process for producing pharmaceutical compositions containing (r)-(e)-4--(3-phosphono-2-propenyl)-2-piperazine-carboxylic acid as active component
US5086072A (en) * 1990-06-18 1992-02-04 The United States Of America As Represented By The Department Of Health And Human Services Treatment of mood disorders with functional antagonists of the glycine/nmda receptor complex
EP0488959A3 (en) * 1990-11-28 1992-08-05 Sandoz Ltd. New uses of competitive nmda receptor antagonists
US5260286A (en) * 1992-10-16 1993-11-09 Japan Tobacco, Inc. 2-piperidinecarboxylic acid derivatives useful as NMDA receptor antagonists
AU5693996A (en) * 1995-05-08 1996-11-29 Lonza A.G. Biotechnical production process of piperazine r-alpha-carbox ylic acids and piperazine s-alpha-carboxylic acid amide
ES2206928T3 (es) 1997-05-12 2004-05-16 Ortho-Mcneil Pharmaceutical, Inc. Piperacinas sustituidas con arilo utiles en el tratamiento de la hiperplasia benigna de prostata.
GB9821179D0 (en) * 1998-09-30 1998-11-25 Merck Sharp & Dohme Therapeutic use
JP2008124531A (ja) 2006-11-08 2008-05-29 Nec Electronics Corp 半導体装置およびオーディオプロセッサチップ
EP3427729A1 (en) 2017-07-13 2019-01-16 Paris Sciences et Lettres - Quartier Latin Probenecid for use in treating epileptic diseases, disorders or conditions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1248531A (en) * 1984-04-17 1989-01-10 Jeffrey C. Watkins 4-substituted piperazine-2-carboxylic acids

Also Published As

Publication number Publication date
PT86776B (pt) 1992-05-29
JPH0723387B2 (ja) 1995-03-15
DK168441B1 (da) 1994-03-28
CH675125A5 (es) 1990-08-31
IL85436A (es) 1992-12-01
HK142093A (en) 1994-01-07
GB2201676A (en) 1988-09-07
FR2610932A1 (fr) 1988-08-19
HUT49361A (en) 1989-09-28
NL8800412A (nl) 1988-09-16
SE8800541D0 (sv) 1988-02-17
CA1327799C (en) 1994-03-15
CY1739A (en) 1995-10-20
GB8803438D0 (en) 1988-03-16
IE880413L (en) 1988-08-18
IT8847631A0 (it) 1988-02-12
GR1002471B (el) 1996-11-15
JPS63203691A (ja) 1988-08-23
PT86776A (pt) 1988-03-01
ZA881146B (en) 1989-10-25
NZ223529A (en) 1991-02-26
KR880009944A (ko) 1988-10-06
HU211269A9 (en) 1995-11-28
ES2011319A6 (es) 1990-01-01
GB8703749D0 (en) 1987-03-25
SE467256B (sv) 1992-06-22
AU1175888A (en) 1988-08-25
DE3804936A1 (de) 1988-09-01
IL85436A0 (en) 1988-07-31
FI86733B (fi) 1992-06-30
IE59098B1 (en) 1994-01-12
HU199858B (en) 1990-03-28
PH25512A (en) 1991-07-24
BE1002427A3 (fr) 1991-02-05
MY103206A (en) 1993-05-29
LU87129A1 (fr) 1988-09-20
FI880744L (fi) 1988-08-19
ATA36788A (de) 1990-03-15
FI86733C (fi) 1992-10-12
DK79688D0 (da) 1988-02-16
IT1219447B (it) 1990-05-18
AT391320B (de) 1990-09-25
AU613009B2 (en) 1991-07-25
KR960015190B1 (ko) 1996-11-01
FI880744A0 (fi) 1988-02-17
DK79688A (da) 1988-08-19
FR2610932B1 (fr) 1990-11-16
GR880100084A (el) 1988-12-16
DE3804936C2 (de) 1997-02-13
GB2201676B (en) 1991-01-02

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Legal Events

Date Code Title Description
PC1A Transfer granted
FD1A Patent lapsed

Effective date: 20041004