ES2026576T3 - Un metodo para controlar la distribucion epimera en la preparacion de 16,17-acetales o cetales de derivados de pregnano. - Google Patents

Un metodo para controlar la distribucion epimera en la preparacion de 16,17-acetales o cetales de derivados de pregnano.

Info

Publication number
ES2026576T3
ES2026576T3 ES198787850282T ES87850282T ES2026576T3 ES 2026576 T3 ES2026576 T3 ES 2026576T3 ES 198787850282 T ES198787850282 T ES 198787850282T ES 87850282 T ES87850282 T ES 87850282T ES 2026576 T3 ES2026576 T3 ES 2026576T3
Authority
ES
Spain
Prior art keywords
distribution
epimeral
pregnano
cetals
acetals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787850282T
Other languages
English (en)
Inventor
Edib Jakupovic
Roy Torvald Sourander
Jan Urban Stenhede
Rolf Peter Svensson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astra Pharmaceutical Production AB
Original Assignee
Astra Pharmaceutical Production AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Pharmaceutical Production AB filed Critical Astra Pharmaceutical Production AB
Application granted granted Critical
Publication of ES2026576T3 publication Critical patent/ES2026576T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

UN METODO PARA EL CONTROL DE LA DISTRIBUCION EPIMERICA EN LA OBTENCION DE 16,17
ES198787850282T 1986-09-25 1987-09-18 Un metodo para controlar la distribucion epimera en la preparacion de 16,17-acetales o cetales de derivados de pregnano. Expired - Lifetime ES2026576T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8604059A SE8604059D0 (sv) 1986-09-25 1986-09-25 A method of controlling the epimeric distribution in the preparation of 16,17-acetals of pregnane derivatives

Publications (1)

Publication Number Publication Date
ES2026576T3 true ES2026576T3 (es) 1992-05-01

Family

ID=20365704

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787850282T Expired - Lifetime ES2026576T3 (es) 1986-09-25 1987-09-18 Un metodo para controlar la distribucion epimera en la preparacion de 16,17-acetales o cetales de derivados de pregnano.

Country Status (13)

Country Link
US (1) US4925933A (es)
EP (1) EP0262108B1 (es)
JP (1) JP2668000B2 (es)
KR (1) KR950014460B1 (es)
AT (1) ATE70066T1 (es)
CY (1) CY1791A (es)
DE (1) DE3774987D1 (es)
ES (1) ES2026576T3 (es)
FI (1) FI90345C (es)
GR (1) GR3003332T3 (es)
HK (1) HK46194A (es)
IL (1) IL83994A (es)
SE (1) SE8604059D0 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8903219D0 (sv) * 1989-10-02 1989-10-02 Astra Ab Process for the manufacture of budesonide
GR1001529B (el) * 1990-09-07 1994-03-31 Elmuquimica Farm Sl Μέ?οδος για την λήψη νέων 21-εστέρων της 16-17-ακετάλης της πρ να-1,4-διενο-3,20-διόνης.
SE9100341D0 (sv) * 1991-02-04 1991-02-04 Astra Ab Novel steroids
FR2675146A1 (fr) * 1991-04-10 1992-10-16 Roussel Uclaf Nouveaux derives sterouides de la pregna-1,4-diene-3,20-dione, leur preparation, leur application a la preparation de derives 16,17-methylene dioxy substitues et nouveaux intermediaires.
GB9423919D0 (en) * 1994-11-26 1995-01-11 Rhone Poulenc Rorer Ltd Chemical process
DE19635498A1 (de) * 1996-09-03 1998-03-26 Byk Gulden Lomberg Chem Fab Verfahren zur Epimerenanreicherung
IT1291288B1 (it) 1997-04-30 1999-01-07 Farmabios Srl Processo per la preparazione di 16,17 acetali di derivati pregnanici con controllo della distribuzione epimerica al c-22.
US6266556B1 (en) 1998-04-27 2001-07-24 Beth Israel Deaconess Medical Center, Inc. Method and apparatus for recording an electroencephalogram during transcranial magnetic stimulation
IT1302657B1 (it) * 1998-10-13 2000-09-29 Farmabios Srl Processo stereoselettivo per la preparazione di budesonide nella formadi epimero 22-r.
MXPA03004123A (es) * 2000-11-10 2004-09-10 Altan Pharma Kg Proceso para la produccion de 16, 17-[(ciclohexilmetilen) bis(oxy)]-11, 21-dihidroxi-pregna-1, 4-dien-3, 20-dion o su 21-isobutirat por trnasquetalisacion.
BR0212767A (pt) 2001-09-25 2004-10-13 Pharmacia & Upjohn Comapny Transacetalização estereosseletiva de acetonida esteriodal c-22
WO2004033478A2 (en) * 2002-10-08 2004-04-22 Sepracor Inc. Fatty acid modified forms of glucocorticoids and their use as anti-inflammatory
EP1869064A2 (en) * 2005-11-02 2007-12-26 Sicor, Inc. Improved process for the preparation of ciclesonide
US20070232578A1 (en) * 2006-02-15 2007-10-04 Pierluigi Rossetto Crystalline forms of ciclesonide
WO2016120891A1 (en) * 2015-01-30 2016-08-04 Coral Drugs Pvt. Ltd. Novel process for preparation of glucocorticoid steroids
KR20250114431A (ko) 2016-11-08 2025-07-29 리제너론 파마슈티칼스 인코포레이티드 스테로이드 및 이의 단백질-접합체
KR20250008984A (ko) 2017-05-18 2025-01-16 리제너론 파마슈티칼스 인코포레이티드 사이클로덱스트린 단백질 약물 접합체
MX2020004691A (es) 2017-11-07 2020-08-20 Regeneron Pharma Enlazadores hidrofilicos para conjugados anticuerpo-farmaco.
CN112004557B (zh) 2018-01-08 2024-07-30 里珍纳龙药品有限公司 类固醇类化合物及其抗体偶联物
CN112533951A (zh) 2018-05-09 2021-03-19 里珍纳龙药品有限公司 抗msr1抗体及其使用方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE378110B (es) * 1972-05-19 1975-08-18 Bofors Ab
SE378109B (es) * 1972-05-19 1975-08-18 Bofors Ab
SE8008524L (sv) * 1980-12-04 1982-06-05 Draco Ab 4-pregnen-derivat, ett forfarande for deras framstellning, beredning och metod for behandling av inflammatoriska tillstand
IT1196142B (it) * 1984-06-11 1988-11-10 Sicor Spa Procedimento per la preparazione di 16,17-acetali di derivati pregnanici e nuovi composti ottenuti

Also Published As

Publication number Publication date
IL83994A (en) 1992-02-16
EP0262108A1 (en) 1988-03-30
GR3003332T3 (en) 1993-02-17
KR950014460B1 (ko) 1995-11-28
EP0262108B1 (en) 1991-12-04
ATE70066T1 (de) 1991-12-15
KR880003969A (ko) 1988-06-01
FI90345C (fi) 1994-01-25
FI874189L (fi) 1988-03-26
US4925933A (en) 1990-05-15
JPS6393795A (ja) 1988-04-25
SE8604059D0 (sv) 1986-09-25
FI90345B (fi) 1993-10-15
FI874189A0 (fi) 1987-09-24
JP2668000B2 (ja) 1997-10-27
IL83994A0 (en) 1988-02-29
DE3774987D1 (de) 1992-01-16
CY1791A (en) 1995-10-20
HK46194A (en) 1994-05-20

Similar Documents

Publication Publication Date Title
ES2026576T3 (es) Un metodo para controlar la distribucion epimera en la preparacion de 16,17-acetales o cetales de derivados de pregnano.
EP0406274A4 (en) New, water soluble, antineoplastic derivatives of taxol
DE68907483D1 (de) Vitamin d analoge.
DE3872624D1 (de) Injektormischer unter druck.
FI892471A7 (fi) Sanitetsvattenkran med i huset parallellt med varandra anordnade ventiltallrikar.
FI914927A0 (fi) Fungicida oxazolidinoner.
DE3868212D1 (de) Ventilsteuerungen.
ES542703A0 (es) Un procedimiento para la preparacion de derivados de tiazol,2, 4, disustituidos.
ES2013631B3 (es) Metodo para el tratamiento de tejidos.
DE69001463D1 (de) Mikroleckregulierventil.
IL83645A0 (en) 2.3.6-substituted phenylimidazole derivatives,processes for the preparation thereof,and the use thereof as growth regulators
ES2022896B3 (es) Derivados de azol utiles para el control de enfermedades vegetales.
ES553377A0 (es) Procedimiento para la produccion de 2,4,6-tris-(amino-fenilamino)-triacinas
IT8720345A0 (it) Macchina per cucire modulare, predisposta per il comando di dispositivi ausiliari.
DE3868937D1 (de) Unter konstantem druck gesteuertes planierschild.
BG38940A3 (en) Method for preparing penicillanoyloxymethyl penicillanate- 1, 1- dioxide
AR240942A1 (es) Un proceso para la preparacion de nuevos derivados de 5-(1-ciano-1-alquil-n-mentil-n-metoxi-fenetil)-alquilamino-2.2.8.-trimetil-4h-dioxino-(4,5-c)-piridina.-
ES2021048B3 (es) Un metodo para la preparacion de un derivado de 2,4-diamino-3oxi-pirimidina.
FI850994A7 (fi) Menetelmä uusien 1,2,4 -triatsasykloalkadieenijohdannaisten valmistamiseksi.
DE3874773D1 (de) Pflanzenwachstumsregulator.
AR244500A1 (es) Agente regulador del crecimiento vegetal.
EP0359118A3 (en) Method for the production of 1,1,2-trialkoxyethanes
DE3680109D1 (de) Myoelektrisch gesteuerte kuenstliche hand.
FI871368A7 (fi) Menetelmä 2,3,4,5-tetrafluori -bentsoyyliasetaattien valmistamiseksi.
PL277837A1 (en) New 5-/substituted amino /-8-/ phenylo or substituted phenylo /-3h, 6h-1, 4, 5a, 8a - tetraazaacenaphtylen-3-ons production method

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 262108

Country of ref document: ES