ES2026666T3 - Procedimiento para preparar derivados de imidazopiridinas. - Google Patents

Procedimiento para preparar derivados de imidazopiridinas.

Info

Publication number
ES2026666T3
ES2026666T3 ES198888400666T ES88400666T ES2026666T3 ES 2026666 T3 ES2026666 T3 ES 2026666T3 ES 198888400666 T ES198888400666 T ES 198888400666T ES 88400666 T ES88400666 T ES 88400666T ES 2026666 T3 ES2026666 T3 ES 2026666T3
Authority
ES
Spain
Prior art keywords
radical
procedure
imidazopyridine derivatives
preparing
preparing imidazopyridine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888400666T
Other languages
English (en)
Inventor
Pascal George
John Allen
Guy Jaurand
Daniele De Peretti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8704277A external-priority patent/FR2612928B1/fr
Priority claimed from FR8704276A external-priority patent/FR2612927B1/fr
Application filed by Synthelabo SA filed Critical Synthelabo SA
Application granted granted Critical
Publication of ES2026666T3 publication Critical patent/ES2026666T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Transplantation (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

DERIVADOS DE IMIDAZOL ]1,2 LA FORMULA EN LA CUAL: Y1 REPRESENTA UN ATOMO DE HIDROGENO O DE HALOGENO O UN RADICAL (C1 RADICAL SR EN EL CUAL R ES H O UN RADICAL (C1 4) ALQUILO O UN RADICAL (ALCOXI EN UN RADICAL (C1 HALOGENO, UN RADICAL (C1 ILO, EL GRUPO CF3, CH3S, NO2 O NH2; R1 Y R2 REPRESENTAN CADA UNO, INDEPENDIENTEMENTE UNO DE OTRO, BIEN UN ATOMO DE HIDROGENO, BIEN UN RADICAL (C1 CION EN TERAPEUTICA.
ES198888400666T 1987-03-27 1988-03-21 Procedimiento para preparar derivados de imidazopiridinas. Expired - Lifetime ES2026666T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8704277A FR2612928B1 (fr) 1987-03-27 1987-03-27 Derives hydroxyles d'imidazopyridines, leur preparation et leur application en therapeutique
FR8704276A FR2612927B1 (fr) 1987-03-27 1987-03-27 Derives d'imidazopyridines, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
ES2026666T3 true ES2026666T3 (es) 1992-05-01

Family

ID=26225872

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888400666T Expired - Lifetime ES2026666T3 (es) 1987-03-27 1988-03-21 Procedimiento para preparar derivados de imidazopiridinas.

Country Status (17)

Country Link
US (1) US4847263A (es)
EP (1) EP0289371B1 (es)
JP (1) JP2733492B2 (es)
KR (1) KR880011155A (es)
AR (1) AR243523A1 (es)
AU (1) AU597809B2 (es)
CA (1) CA1324139C (es)
DE (1) DE3865073D1 (es)
DK (1) DK167388A (es)
ES (1) ES2026666T3 (es)
FI (1) FI881434A7 (es)
GR (1) GR3003145T3 (es)
HU (1) HU198048B (es)
IL (1) IL85840A (es)
NO (1) NO881333L (es)
NZ (1) NZ224032A (es)
PT (1) PT87090B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4791117A (en) * 1986-09-22 1988-12-13 Ortho Pharmaceutical Corporation 2- or 3-aryl substituted imidazo[1,2-a]pyridines and their use as calcium channel blockers
US5032595A (en) * 1989-11-24 1991-07-16 Fidia-Georgetown Institute For The Neurosciences Method of stimulating steroidogenesis with alpidem
FR2727864B1 (fr) 1994-12-12 1997-04-04 Synthelabo Utilisation des ligands des sites de liaison peripherique pour les benzodiazepines pour la preparation de medicaments utiles dans le traitement des neuropathies peripheriques
AUPP278498A0 (en) 1998-04-03 1998-04-30 Australian Nuclear Science & Technology Organisation Peripheral benzodiazepine receptor binding agents
US6908929B2 (en) 2000-03-31 2005-06-21 Ortho-Mcneil Pharmaceutical, Inc. Phenyl-substituted imidazopyridines
WO2001074813A2 (en) * 2000-03-31 2001-10-11 Ortho Mcneil Pharmaceutical, Inc. METHOD FOR USING 2- OR 3-ARYL SUBSTITUTED IMIDAZO[1,2-a] PYRIDINES AS H3 ANTAGONISTS
CZ20023775A3 (cs) * 2000-04-24 2003-10-15 Teva Pharmaceutical Industries Ltd. Zolpidem hemitartrát
EP1475093B1 (en) 2000-04-24 2006-09-06 Teva Pharmaceutical Industries Ltd. Micronized Zolpidem hemitartrate
EP1539751B1 (en) 2002-07-15 2008-05-07 Scinopharm Taiwan, Ltd. Process for the preparation of imidazo(1,2-a)pyridine-3-acetamides
EP1575952B1 (en) * 2002-12-18 2009-02-18 Mallinckrodt Inc. Synthesis of heteroaryl acetamides
WO2006008636A2 (en) * 2004-07-16 2006-01-26 Ranbaxy Laboratories Limited Processes for the preparation of zolpidem and its hemitartrate

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1442707A (en) * 1973-07-07 1976-07-14 Yoshitomi Pharmaceutical Substituted phenylalkanoic acids and their derivatives and pharma ceutical compositions thereof
US4221796A (en) * 1979-09-19 1980-09-09 E. R. Squibb & Sons, Inc. Substituted imidazolo-pyridines and method
FR2492382A1 (fr) * 1980-10-22 1982-04-23 Synthelabo Derives d'imidazo (1,2-a) pyridine, leur preparation et leur application en therapeutique
FR2568880B1 (fr) * 1984-08-07 1986-12-12 Synthelabo Derives d'acylaminomethyl-3 imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique
ATE62687T1 (de) * 1986-01-22 1991-05-15 Synthelabo Acylaminomethylimidazo(1,2-a>pyrimidinderivate, ihre herstellung und therapeutische verwendung.
FR2599368B1 (fr) * 1986-06-02 1988-08-05 Synthelabo Derives hydroxyles d'imidazopyridines, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
PT87090B (pt) 1992-07-31
JP2733492B2 (ja) 1998-03-30
PT87090A (pt) 1988-04-01
EP0289371A1 (fr) 1988-11-02
AU597809B2 (en) 1990-06-07
FI881434A7 (fi) 1988-09-28
DK167388D0 (da) 1988-03-25
HU198048B (en) 1989-07-28
GR3003145T3 (en) 1993-02-17
FI881434A0 (fi) 1988-03-25
NO881333L (no) 1988-09-28
JPS63258475A (ja) 1988-10-25
KR880011155A (ko) 1988-10-26
EP0289371B1 (fr) 1991-09-25
CA1324139C (en) 1993-11-09
US4847263A (en) 1989-07-11
IL85840A0 (en) 1988-09-30
DK167388A (da) 1988-09-28
NO881333D0 (no) 1988-03-25
DE3865073D1 (de) 1991-10-31
HUT46692A (en) 1988-11-28
AU1373688A (en) 1988-09-29
NZ224032A (en) 1990-05-28
AR243523A1 (es) 1993-08-31
IL85840A (en) 1992-03-29

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