ES2029795T3 - Un procedimiento para la preparacion de compuestos amino-heterociclicos. - Google Patents

Un procedimiento para la preparacion de compuestos amino-heterociclicos.

Info

Publication number
ES2029795T3
ES2029795T3 ES198686308208T ES86308208T ES2029795T3 ES 2029795 T3 ES2029795 T3 ES 2029795T3 ES 198686308208 T ES198686308208 T ES 198686308208T ES 86308208 T ES86308208 T ES 86308208T ES 2029795 T3 ES2029795 T3 ES 2029795T3
Authority
ES
Spain
Prior art keywords
compounds
amino
procedure
preparation
cyclic compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198686308208T
Other languages
English (en)
Inventor
John Kitchin
Peter Clive Cherry
Alan David Borthwick
Adrian John Pipe
Derek Burn
Richard John Coles
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ES2029795T3 publication Critical patent/ES2029795T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrane Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

COMPRENDEN LA FORMULA (I) DONDE R ES H, O ALQUIL C 1 A 6, ALQUIL SUSTITUIDO C 1 A 6 POR CICLOALQUIL C 3 A 7, ALQUENIL C 3 A 6, ALQUINIL C 3 A 6, CICLOALQUIL C 3 A 7, O ARALQUIL (EN EL CUAL LA MOLECULA DE ALQUIL CONTIENE DE C 1 A 5); R1 Y R2 REPRESENTAN CADA UNO, INDEPENDIENTEMENTE, FLUORINA O CLORINA O UNO DE R1 Y R2 SON H, Y LAS SALES FISIOLOGICAMENTE ACEPTABLES DEL MISMO. EL COMPUESTO PUEDE SER PREPARADO POR AMINACION DE UN COMPUESTO DE FORMULA (II) DONDE X ES UN GRUPO CEDENTE CON AMONIO O UN AMONIO APROPIADO. TIENEN APLICACION EN EL TRATAMIENTO DE DESORDENES TALES COMO LA DEPRESION.
ES198686308208T 1985-10-23 1986-10-22 Un procedimiento para la preparacion de compuestos amino-heterociclicos. Expired - Lifetime ES2029795T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858526210A GB8526210D0 (en) 1985-10-23 1985-10-23 Chemical compounds

Publications (1)

Publication Number Publication Date
ES2029795T3 true ES2029795T3 (es) 1992-10-01

Family

ID=10587163

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198686308208T Expired - Lifetime ES2029795T3 (es) 1985-10-23 1986-10-22 Un procedimiento para la preparacion de compuestos amino-heterociclicos.

Country Status (11)

Country Link
EP (1) EP0224332B1 (es)
JP (1) JPS62103078A (es)
AT (1) ATE55388T1 (es)
AU (1) AU584247B2 (es)
DE (1) DE3673348D1 (es)
DK (1) DK507186A (es)
ES (1) ES2029795T3 (es)
GB (2) GB8526210D0 (es)
GR (1) GR3000988T3 (es)
NZ (1) NZ218034A (es)
ZA (1) ZA868019B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225431A (en) * 1987-10-23 1993-07-06 Burroughs Wellcome Co. Therapeutic substituted indole compounds and compositions thereof
AU5272296A (en) * 1995-04-06 1996-10-23 Novo Nordisk A/S Benzopyranopyrrole compounds, their preparation and use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL70034A0 (en) * 1982-10-25 1984-01-31 Glaxo Group Ltd Heterocyclic amino compounds,their preparation and pharmaceutical compositions containing them
GB8410459D0 (en) * 1984-04-24 1984-05-31 Glaxo Group Ltd Chemical compounds
GB2201414B (en) * 1984-04-24 1988-12-29 Glaxo Group Ltd Heterocyclic amino compounds

Also Published As

Publication number Publication date
JPS62103078A (ja) 1987-05-13
DE3673348D1 (de) 1990-09-13
EP0224332A1 (en) 1987-06-03
GB2182040A (en) 1987-05-07
AU584247B2 (en) 1989-05-18
GB8526210D0 (en) 1985-11-27
ATE55388T1 (de) 1990-08-15
AU6435286A (en) 1987-04-30
DK507186A (da) 1987-04-24
GB2182040B (en) 1989-10-11
EP0224332B1 (en) 1990-08-08
DK507186D0 (da) 1986-10-22
NZ218034A (en) 1989-07-27
ZA868019B (en) 1987-07-29
GB8625264D0 (en) 1986-11-26
GR3000988T3 (en) 1991-12-10

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