ES2031238T3 - Aparato distribuidor con matriz movil que incluye una pluralidad de pildoras de tamano reducido. - Google Patents

Aparato distribuidor con matriz movil que incluye una pluralidad de pildoras de tamano reducido.

Info

Publication number
ES2031238T3
ES2031238T3 ES198888305757T ES88305757T ES2031238T3 ES 2031238 T3 ES2031238 T3 ES 2031238T3 ES 198888305757 T ES198888305757 T ES 198888305757T ES 88305757 T ES88305757 T ES 88305757T ES 2031238 T3 ES2031238 T3 ES 2031238T3
Authority
ES
Spain
Prior art keywords
pills
reduced size
matrix including
distributor device
mobile matrix
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888305757T
Other languages
English (en)
Inventor
Felix Theeuwes
Patrick W.-L. Wong
Richard Cortese
James B. Eckenhoff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of ES2031238T3 publication Critical patent/ES2031238T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0068—Rumen, e.g. rumen bolus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

SE DESCRIBE UN MEDICAMENTO PARA SUMINISTRAR PILDORAS DIMINUTOAS A UN ENTORNO DE USO. EL MEDICAMENTO COMPRENDE UNA PARED QUE RODEA UN ESPACIO INTERNO, QUE COMPRENDE UN PRIMER MEDIO EN EL MEDICAMENTO PARA CAMBIAR DE UN ESTADO DE MEDICAMENTO A UN ENTORNO DE ESTADO DE USO DEJANDO EL MEDICAMENTO, PILDORAS DIMINUTAS EN EL PRIMER MEDIO, Y UN SEGUNDO MEDIO EN EL MEDICAMENTO PARA AYUDAR A DESPLAZAR EL PRIMER MEDIO DEL MEDICAMENTO
ES198888305757T 1987-07-13 1988-06-24 Aparato distribuidor con matriz movil que incluye una pluralidad de pildoras de tamano reducido. Expired - Lifetime ES2031238T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/072,506 US4824675A (en) 1987-07-13 1987-07-13 Dispenser with movable matrix comprising a plurality of tiny pills

Publications (1)

Publication Number Publication Date
ES2031238T3 true ES2031238T3 (es) 1992-12-01

Family

ID=22108037

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888305757T Expired - Lifetime ES2031238T3 (es) 1987-07-13 1988-06-24 Aparato distribuidor con matriz movil que incluye una pluralidad de pildoras de tamano reducido.

Country Status (7)

Country Link
US (1) US4824675A (es)
EP (1) EP0300623B1 (es)
JP (1) JPS6431710A (es)
AU (1) AU613040B2 (es)
CA (1) CA1319071C (es)
DE (1) DE3871273D1 (es)
ES (1) ES2031238T3 (es)

Families Citing this family (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4940465A (en) * 1987-05-27 1990-07-10 Felix Theeuwes Dispenser comprising displaceable matrix with solid state properties
US4892778A (en) * 1987-05-27 1990-01-09 Alza Corporation Juxtaposed laminated arrangement
GB8730011D0 (en) * 1987-12-23 1988-02-03 Smithkline Dauelsberg Pharmaceutical compositions
JPH03504246A (ja) * 1988-05-16 1991-09-19 アメリカ合衆国 エイズのための化学療法剤組成物
DK0384646T3 (da) * 1989-02-16 1993-07-12 British Tech Group Dispenseringsindretning
US5019396A (en) * 1989-05-12 1991-05-28 Alza Corporation Delivery dispenser for treating cardiac arrhythmias
US5273752A (en) * 1989-07-18 1993-12-28 Alza Corporation Controlled release dispenser comprising beneficial agent
US5035897A (en) * 1989-09-05 1991-07-30 Alza Corporation Dosage form for delivering soluble or insoluble drugs
US5013557A (en) * 1989-10-03 1991-05-07 Warner-Lambert Company Taste masking compositions comprising spray dried microcapsules containing sucralfate and methods for preparing same
US5576306A (en) * 1991-03-01 1996-11-19 Dow Chemical Company Pharmaceutical compositions and uses of water-soluble, high-viscosity grade cellulose ethers
US5721221A (en) * 1991-03-08 1998-02-24 Regents Of The University Of Minnesota Lowering blood cholesterol levels using water soluble cellulose ethers
US5240713A (en) * 1991-09-27 1993-08-31 Alza Corporation Dual rate agent delivery device
US5462741A (en) * 1992-08-06 1995-10-31 Alza Corporation High agent loaded controlled release dispenser
US5315190A (en) * 1992-12-22 1994-05-24 Stirling Technology Company Linear electrodynamic machine and method of using same
US6440457B1 (en) * 1993-05-27 2002-08-27 Alza Corporation Method of administering antidepressant dosage form
US5399359A (en) * 1994-03-04 1995-03-21 Edward Mendell Co., Inc. Controlled release oxybutynin formulations
IE940292A1 (en) * 1994-04-06 1995-10-18 Elan Corp Plc Biodegradable microcapsules and method for their manufacture
US5399362A (en) * 1994-04-25 1995-03-21 Edward Mendell Co., Inc. Once-a-day metoprolol oral dosage form
US5629021A (en) * 1995-01-31 1997-05-13 Novavax, Inc. Micellar nanoparticles
US5698210A (en) * 1995-03-17 1997-12-16 Lee County Mosquito Control District Controlled delivery compositions and processes for treating organisms in a column of water or on land
US5674895A (en) * 1995-05-22 1997-10-07 Alza Corporation Dosage form comprising oxybutynin
US6124355A (en) * 1995-05-22 2000-09-26 Guittard; George V. Oxybutynin therapy
US6262115B1 (en) * 1995-05-22 2001-07-17 Alza Coporation Method for the management of incontinence
US5912268A (en) * 1995-05-22 1999-06-15 Alza Corporation Dosage form and method for treating incontinence
AU2068797A (en) * 1996-01-29 1997-08-20 Edward Mendell Co. Inc. Sustained release excipient
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
US20040062799A1 (en) * 1997-09-29 2004-04-01 Ayer Atul D. Therapeutic composition and delivery system for administering drug
WO1999051208A1 (en) * 1998-04-03 1999-10-14 Bm Research A/S Controlled release composition
PT1083879E (pt) * 1998-06-03 2005-01-31 Alza Corp Metodos e dispositivos para proporcionar uma terapia de drogas prolongada
AUPR610501A0 (en) * 2001-07-04 2001-07-26 Smart Drug Systems Inc Treatment of parasitic disease
US20040234602A1 (en) 2001-09-21 2004-11-25 Gina Fischer Polymer release system
EP1429744A1 (en) * 2001-09-21 2004-06-23 Egalet A/S Morphine polymer release system
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
US6663888B2 (en) * 2001-12-14 2003-12-16 Eurand Pharmaceuticals Ltd. Pulsatile release histamine H2 antagonist dosage form
US20050025824A1 (en) * 2001-12-14 2005-02-03 Eurand Pharmaceuticals Ltd. Pulsatile release histamine H2 antagonist dosage form
CA2481091A1 (en) * 2002-04-05 2003-10-23 Penwest Pharmaceuticals Co. Sustained release metoprolol formulations
AR039744A1 (es) * 2002-06-26 2005-03-09 Alza Corp Metodos y formas de dosificacion para aumentar la solubilidad de las composiciones de farmacos para la administracion controlada
NZ537543A (en) * 2002-07-29 2007-08-31 Alza Corp Formulations and high dose osmotic dosage forms for controlled delivery of topiramate
US20050208132A1 (en) * 2002-07-29 2005-09-22 Gayatri Sathyan Methods and dosage forms for reducing side effects of benzisozazole derivatives
US20050232995A1 (en) * 2002-07-29 2005-10-20 Yam Nyomi V Methods and dosage forms for controlled delivery of paliperidone and risperidone
US8367111B2 (en) * 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
EP1610768B1 (en) * 2003-03-26 2008-07-02 Egalet A/S Matrix compositions for controlled delivery of drug substances
WO2004084868A1 (en) 2003-03-26 2004-10-07 Egalet A/S Morphine controlled release system
AU2004264316A1 (en) * 2003-08-06 2005-02-24 Alza Corporation Uniform delivery of topiramate over prolonged period of time with enhanced dispersion formulation
MXPA06002067A (es) * 2003-08-22 2006-08-11 Johnson & Johnson Suministro gradual de topiramato durante periodo prolongado.
AU2004268661A1 (en) * 2003-09-02 2005-03-10 Alza Corporation Novel drug compositions and dosage forms of topiramate
JP2007516297A (ja) * 2003-12-23 2007-06-21 アルザ・コーポレーシヨン 制御送達用薬剤組成物の溶解度を高くする方法および投薬形態物
JP2007517063A (ja) * 2003-12-29 2007-06-28 アルザ・コーポレーシヨン トピラメートの新規な薬剤組成物および剤形
US20050175696A1 (en) * 2003-12-29 2005-08-11 David Edgren Drug granule coatings that impart smear resistance during mechanical compression
AU2004312082A1 (en) * 2003-12-29 2005-07-21 Alza Corporation, Inc. Novel drug compositions and dosage forms
US7713539B2 (en) * 2004-07-19 2010-05-11 Boston Scientific Scimed, Inc. Medical devices containing radiation resistant block copolymer
US8747895B2 (en) * 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
NZ728442A (en) 2004-10-21 2018-05-25 Adare Pharmaceuticals Inc Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
US20060105038A1 (en) * 2004-11-12 2006-05-18 Eurand Pharmaceuticals Limited Taste-masked pharmaceutical compositions prepared by coacervation
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
NZ563846A (en) * 2005-06-03 2010-03-26 Egalet As A drug delivery system for delivering active substances dispersed in a dispersion medium
US8778395B2 (en) 2005-08-11 2014-07-15 Andrx Labs, Llc Diltiazem controlled release formulation and method of manufacture
US7538652B2 (en) * 2006-08-29 2009-05-26 International Business Machines Corporation Electrical component tuned by conductive layer deletion
EP2104493A2 (en) * 2007-01-16 2009-09-30 Egalet A/S Use of i) a polyglycol and n) an active drug substance for the preparation of a pharmaceutical composition for i) mitigating the risk of alcohol induced dose dumping and/or ii) reducing the risk of drug abuse
US8821928B2 (en) 2007-06-04 2014-09-02 Egalet Ltd. Controlled release pharmaceutical compositions for prolonged effect
CA2751667C (en) 2009-02-06 2016-12-13 Egalet Ltd. Immediate release composition resistant to abuse by intake of alcohol
NZ597283A (en) 2009-06-24 2013-07-26 Egalet Ltd Controlled release formulations
AU2010325746B2 (en) 2009-12-02 2016-02-25 Adare Pharmaceuticals S.R.L. Fexofenadine microcapsules and compositions containing them
US9400873B2 (en) 2011-12-21 2016-07-26 Deka Products Limited Partnership System, method, and apparatus for dispensing oral medications
CA2877102C (en) 2011-06-29 2020-06-30 Avidas Pharmaceuticals Llc Topical formulations including lipid microcapsule delivery vehicles and their uses
US10563681B2 (en) 2011-12-21 2020-02-18 Deka Products Limited Partnership System, method, and apparatus for clamping
US12205697B2 (en) 2011-12-21 2025-01-21 Deka Products Limited Partnership Pill dispenser
AU2013285988A1 (en) 2012-07-06 2015-02-12 Egalet Ltd. Abuse deterrent pharmaceutical compositions for controlled release
CN104274411B (zh) * 2014-10-28 2017-01-11 郑州合润生物制药有限公司 一种替米考星微米制剂及其制备方法
WO2017136745A1 (en) * 2016-02-05 2017-08-10 Entrega Inc. Oral dosage form with drying agent for delivery of active agent
CN112437678A (zh) * 2018-05-04 2021-03-02 先进医疗解决方案以色列(西兰迪斯)公司 重构和混合系统

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3995632A (en) * 1973-05-04 1976-12-07 Alza Corporation Osmotic dispenser
US3946734A (en) * 1975-02-19 1976-03-30 The United States Of America As Represented By The Secretary Of State Apparatus for controlling the release of a drug
AU520409B2 (en) * 1977-05-25 1982-01-28 Commonwealth Scientific And Industrial Research Organisation Controlled release composition
US4350271A (en) * 1980-08-22 1982-09-21 Alza Corporation Water absorbing fluid dispenser
US4327725A (en) * 1980-11-25 1982-05-04 Alza Corporation Osmotic device with hydrogel driving member
US4434153A (en) * 1982-03-22 1984-02-28 Alza Corporation Drug delivery system comprising a reservoir containing a plurality of tiny pills
US4659558A (en) * 1982-03-22 1987-04-21 Alza Corporation Oral delivery system comprising a plurality of tiny pills for delivering drug in the stomach and intestine
US4764380A (en) * 1982-03-22 1988-08-16 Alza Corporation Drug delivery system comprising a volume increasing matrix containing a plurality of tiny pills
US4612008A (en) * 1983-05-11 1986-09-16 Alza Corporation Osmotic device with dual thermodynamic activity
US4595583A (en) * 1984-03-19 1986-06-17 Alza Corporation Delivery system controlled administration of beneficial agent to ruminants
US4772474A (en) * 1985-08-09 1988-09-20 Alza Corporation Dispenser with internal arrangement of lamina means for dispensing beneficial agent
US4717566A (en) * 1984-03-19 1988-01-05 Alza Corporation Dosage system and method of using same
GB2155889B (en) * 1984-03-21 1988-03-02 Alza Corp Dispenser-capsule
US4609374A (en) * 1985-04-22 1986-09-02 Alza Corporation Osmotic device comprising means for governing initial time of agent release therefrom
US4717718A (en) * 1985-08-09 1988-01-05 Alza Corporation Device for the controlled delivery of a beneficial agent
US4675174A (en) * 1985-08-16 1987-06-23 Alza Corporation Veterinary dispenser delivering beneficial agent by gas power generated in situ
CH668187A5 (de) * 1986-08-07 1988-12-15 Ciba Geigy Ag Therapeutisches system mit systemischer wirkung.

Also Published As

Publication number Publication date
JPS6431710A (en) 1989-02-02
AU1651788A (en) 1989-01-19
EP0300623A3 (en) 1989-03-22
AU613040B2 (en) 1991-07-25
US4824675A (en) 1989-04-25
EP0300623A2 (en) 1989-01-25
CA1319071C (en) 1993-06-15
EP0300623B1 (en) 1992-05-20
DE3871273D1 (de) 1992-06-25

Similar Documents

Publication Publication Date Title
ES2031238T3 (es) Aparato distribuidor con matriz movil que incluye una pluralidad de pildoras de tamano reducido.
ES2031597T3 (es) Aparato distribuidor con un miembro dispensador para entregar un agente beneficioso.
ES2041988T3 (es) Dispositivo que comprende medios para proteger y suministrar medicamento sensible y fluido.
ES2075444T3 (es) Sistema de dosificado osmotico para la administracion de un farmaco liquido.
ES2041238T1 (es) Matriz de difusion para la administracion de medicamento por via percutanea y dispositivo de administracion de medicamento por via percutanea que los incluye.
ES198343Y (es) Dispositivo para la introduccion de una medicacion liquida.
AR192502A1 (es) Cuerpos portadores de substancias activas medicamentosas y procedimiento para la produccion de medicamentos a base de los mismos
DE69322077D1 (de) Auf hydroxyethylzellulose basierende oralen arzneidosisformen mit verzoegerter wirkstoffabgabe
ES2180251T3 (es) Comprimido revestido con polimero, que contiene amoxicilina y clavulanato.
ES281323U (es) Un modulo calentador para calentar un fluido intravenoso
GR38283B (el) Διαγνωστικον μεσον προς αποδειξιν των εις τα υγρατου σωματος περιεχομενων ουσιων.
CA1009109A (en) Medicament injector
ES2173891T3 (es) Sistema de liberacion pulsatil de un farmaco multiparticulado.
ES2177609T3 (es) Pluma de administracion de medicacion con una escala para fijacion de la dosis.
DK0421541T3 (da) Tabletstruktur, som kan deles
IT1008062B (it) Dispositivo per il miscelamento e la somministrazione di un fluido endovena
BE811386A (fr) Medicament microencapsule
CA992784A (en) Mass transfer diffusion devices having membrane support comprising photoinsolubilized plastic
TR17729A (tr) Tibbi mayi verme cihazi ve bircok tibbi mayinin verilmesine mahsus usul
IT984150B (it) Sistema di indirizzamento perfe zionato particolarmente per me morie di calcolatori e simili
CA1006060A (en) Device for administration of medicines
GB1385521A (en) Osmotic pressure activated active agent dispenser
AU5487173A (en) Capacitive memory type gas discharge display device
IT966120B (it) Dispositivo erogatore e distribu tore di fluidi
BE785378A (fr) Benzoyl-urees, leur preparation et medicament contenant ces substances

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 300623

Country of ref document: ES