ES2031846T3 - MEDICAL COMPOUND CONTAINING TPA AND USE OF THE SAME. - Google Patents
MEDICAL COMPOUND CONTAINING TPA AND USE OF THE SAME.Info
- Publication number
- ES2031846T3 ES2031846T3 ES87104825T ES87104825T ES2031846T3 ES 2031846 T3 ES2031846 T3 ES 2031846T3 ES 87104825 T ES87104825 T ES 87104825T ES 87104825 T ES87104825 T ES 87104825T ES 2031846 T3 ES2031846 T3 ES 2031846T3
- Authority
- ES
- Spain
- Prior art keywords
- same
- compound containing
- medical compound
- containing tpa
- tpa
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 102000003978 Tissue Plasminogen Activator Human genes 0.000 abstract 2
- 108090000373 Tissue Plasminogen Activator Proteins 0.000 abstract 2
- 229960000187 tissue plasminogen activator Drugs 0.000 abstract 2
- MBBZMMPHUWSWHV-BDVNFPICSA-N N-methylglucamine Chemical compound CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO MBBZMMPHUWSWHV-BDVNFPICSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229960003194 meglumine Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/49—Urokinase; Tissue plasminogen activator
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A medical composition contains a tissue Plasminogen Activator (tPA) in combination with meglumine or a salt thereof. The use of the composition in the preparation of a medicament for the treatment of circulatory disorders is also disclosed.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61074370A JPH0678241B2 (en) | 1986-04-02 | 1986-04-02 | tPA pharmaceutical composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2031846T3 true ES2031846T3 (en) | 1996-07-16 |
Family
ID=13545204
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES87104825T Expired - Lifetime ES2031846T3 (en) | 1986-04-02 | 1987-04-01 | MEDICAL COMPOUND CONTAINING TPA AND USE OF THE SAME. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4985245A (en) |
| EP (1) | EP0242653B1 (en) |
| JP (1) | JPH0678241B2 (en) |
| AT (1) | ATE56147T1 (en) |
| CA (1) | CA1289472C (en) |
| DE (1) | DE3764697D1 (en) |
| ES (1) | ES2031846T3 (en) |
| GR (1) | GR3000751T3 (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2520975B2 (en) * | 1989-09-21 | 1996-07-31 | 三井東圧化学株式会社 | Thrombolytic agent containing tissue plasminogen activator or its derivative |
| DE3942141A1 (en) * | 1989-12-20 | 1991-06-27 | Boehringer Mannheim Gmbh | K2P PRO STABILIZATION |
| DE3942142A1 (en) * | 1989-12-20 | 1991-06-27 | Boehringer Mannheim Gmbh | STABILIZATION OF GLYCOSYLATED T-PA |
| DE3942143A1 (en) * | 1989-12-20 | 1991-06-27 | Boehringer Mannheim Gmbh | T-PA PRO STABILIZATION |
| GB0007239D0 (en) * | 2000-03-24 | 2000-05-17 | Nycomed Imaging As | Use |
| JP5468221B2 (en) * | 2008-08-04 | 2014-04-09 | 株式会社 メドレックス | Intravenous dispersion formulation of poorly soluble drugs |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5137343B2 (en) * | 1972-12-07 | 1976-10-15 | ||
| US4647447A (en) * | 1981-07-24 | 1987-03-03 | Schering Aktiengesellschaft | Diagnostic media |
| DE3584902D1 (en) * | 1984-02-29 | 1992-01-30 | Asahi Chemical Ind | AQUEOUS SOLUTION OF AN INCREASED CONCENTRATION OF TISSUE PLASMINOGEN ACTIVATOR AND PRODUCTION METHOD. |
-
1986
- 1986-04-02 JP JP61074370A patent/JPH0678241B2/en not_active Expired - Lifetime
-
1987
- 1987-04-01 DE DE8787104825T patent/DE3764697D1/en not_active Expired - Fee Related
- 1987-04-01 ES ES87104825T patent/ES2031846T3/en not_active Expired - Lifetime
- 1987-04-01 CA CA000533589A patent/CA1289472C/en not_active Expired - Fee Related
- 1987-04-01 AT AT87104825T patent/ATE56147T1/en not_active IP Right Cessation
- 1987-04-01 EP EP87104825A patent/EP0242653B1/en not_active Expired - Lifetime
-
1989
- 1989-11-03 US US07/430,949 patent/US4985245A/en not_active Expired - Fee Related
-
1990
- 1990-09-06 GR GR90400232T patent/GR3000751T3/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE56147T1 (en) | 1990-09-15 |
| JPH0678241B2 (en) | 1994-10-05 |
| JPS62234030A (en) | 1987-10-14 |
| DE3764697D1 (en) | 1990-10-11 |
| US4985245A (en) | 1991-01-15 |
| EP0242653B1 (en) | 1990-09-05 |
| EP0242653A1 (en) | 1987-10-28 |
| GR3000751T3 (en) | 1991-10-10 |
| CA1289472C (en) | 1991-09-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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