ES2031855T3 - Un metodo para preparar una composicion para reducir la presion intraocular en mamiferos. - Google Patents
Un metodo para preparar una composicion para reducir la presion intraocular en mamiferos.Info
- Publication number
- ES2031855T3 ES2031855T3 ES198787110341T ES87110341T ES2031855T3 ES 2031855 T3 ES2031855 T3 ES 2031855T3 ES 198787110341 T ES198787110341 T ES 198787110341T ES 87110341 T ES87110341 T ES 87110341T ES 2031855 T3 ES2031855 T3 ES 2031855T3
- Authority
- ES
- Spain
- Prior art keywords
- group
- radicals
- intraocular pressure
- mammals
- preparing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 241000124008 Mammalia Species 0.000 title abstract 2
- 230000004410 intraocular pressure Effects 0.000 title abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000003291 dopaminomimetic effect Effects 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/58—Radicals substituted by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Ophthalmology & Optometry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Quinoline Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Indole Compounds (AREA)
Abstract
COMPUESTOS NUEVOS QUE POSEEN POR FORMULA ESTRUCTURAL (I), EN DONDE R2, R3 Y R4 SELECCIONADOS CADA UNO DEL GRUPO QUE CONSISTE EN H Y OA; A ES H O ES SELECCIONADO DEL GRUPO QUE CONSISTE EN RADICALES DE HIDROCARBONIL, P.E. RADICALES DE ALQUILO INFERIOR, I.E. METILO, ETILO, PROPILO, ETC.. O (II) EN DONDE R5 ES SELECCIONADO DEL GRUPO QUE CONSISTE EN RADICALES HIDROCARBONILO,P.E. ALQUILO Y RESIDUOS AROMATICOS; N ES 2 O 3; Y R1 ES SELECCIONEDO DEL GRUPO QUE CONSISTE EN RADICALES ORGANICOS QUE POSEEN ANILLOS AROMATICOS FUSIONADOS, ESTO ES, LOS RADICALES QUE COMPRENDEN AL MENOS DOS ANILLOS QUE SEPARAN UN PAR DE ATOMOS DE CARBONO O SEPARAN UN CARBONO Y UN ATOMO DE NITROGENO SON UTILIZADOS PARA INDUCIR UNA RESPUESTA DOPAMINERGICA Y REDUCIR LA PRESION INTRAOCULAR EN UN MAMIFERO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89122386A | 1986-07-28 | 1986-07-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2031855T3 true ES2031855T3 (es) | 1993-01-01 |
Family
ID=25397807
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES198787110341T Expired - Lifetime ES2031855T3 (es) | 1986-07-28 | 1987-07-17 | Un metodo para preparar una composicion para reducir la presion intraocular en mamiferos. |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0254989B1 (es) |
| JP (1) | JPS6335547A (es) |
| AT (1) | ATE56944T1 (es) |
| AU (1) | AU605777B2 (es) |
| DE (1) | DE3765206D1 (es) |
| ES (1) | ES2031855T3 (es) |
| GR (1) | GR3000877T3 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4885308A (en) * | 1984-08-13 | 1989-12-05 | Nelson Research & Development Co. | Method and compositions for treatment of parkinsonism syndrome in mammals |
| DE3719924A1 (de) * | 1986-12-22 | 1988-06-30 | Bayer Ag | 8-substituierte 2-aminotetraline |
| WO1995005176A1 (en) * | 1993-08-18 | 1995-02-23 | Alcon Laboratories, Inc. | Use of ergoline derivatives for the treatment of glaucoma |
| US20050032873A1 (en) * | 2003-07-30 | 2005-02-10 | Wyeth | 3-Amino chroman and 2-amino tetralin derivatives |
| JP6177061B2 (ja) * | 2012-09-12 | 2017-08-09 | キッセイ薬品工業株式会社 | 新規なドパミンｄ２受容体アゴニスト |
| AU2021368924B2 (en) | 2020-10-27 | 2024-07-11 | Guangzhou Henovcom Bioscience Co., Ltd. | Tetrahydronaphthalene compounds, pharmaceutical compositions, and uses thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4657925A (en) * | 1984-08-13 | 1987-04-14 | Nelson Research & Development Co. | Method and compositions for reducing the intraocular pressure of mammals |
| AU573828B2 (en) * | 1984-05-17 | 1988-06-23 | E.R. Squibb & Sons, Inc. | Tetrahydronaphthalenols |
| DE3479314D1 (en) * | 1984-05-22 | 1989-09-14 | Nelson Res & Dev | Substituted 2-aminotetralins and processes for synthesis |
-
1987
- 1987-07-17 DE DE8787110341T patent/DE3765206D1/de not_active Expired - Fee Related
- 1987-07-17 AT AT87110341T patent/ATE56944T1/de not_active IP Right Cessation
- 1987-07-17 ES ES198787110341T patent/ES2031855T3/es not_active Expired - Lifetime
- 1987-07-17 EP EP87110341A patent/EP0254989B1/en not_active Expired - Lifetime
- 1987-07-28 AU AU76197/87A patent/AU605777B2/en not_active Ceased
- 1987-07-28 JP JP62188675A patent/JPS6335547A/ja active Pending
-
1990
- 1990-09-27 GR GR90400635T patent/GR3000877T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GR3000877T3 (en) | 1991-11-15 |
| DE3765206D1 (de) | 1990-10-31 |
| EP0254989A2 (en) | 1988-02-03 |
| EP0254989A3 (en) | 1988-09-21 |
| ATE56944T1 (de) | 1990-10-15 |
| JPS6335547A (ja) | 1988-02-16 |
| EP0254989B1 (en) | 1990-09-26 |
| AU7619787A (en) | 1988-02-04 |
| AU605777B2 (en) | 1991-01-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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