ES2033831T3 - Una composicion a base de hierro y metodo para el tratamiento del cancer. - Google Patents

Una composicion a base de hierro y metodo para el tratamiento del cancer.

Info

Publication number
ES2033831T3
ES2033831T3 ES198787302323T ES87302323T ES2033831T3 ES 2033831 T3 ES2033831 T3 ES 2033831T3 ES 198787302323 T ES198787302323 T ES 198787302323T ES 87302323 T ES87302323 T ES 87302323T ES 2033831 T3 ES2033831 T3 ES 2033831T3
Authority
ES
Spain
Prior art keywords
iron
gamma
linolenic acid
acids
cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787302323T
Other languages
English (en)
Inventor
David Frederick Horrobin
Michel Edgar Begin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Efamol Holdings PLC
Original Assignee
Efamol Holdings PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Efamol Holdings PLC filed Critical Efamol Holdings PLC
Application granted granted Critical
Publication of ES2033831T3 publication Critical patent/ES2033831T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

COMPOSICIONES FARMACEUTICAMENTE ACEPTABLES DE UNO O MAS ACIDOS GRASOS ESENCIALES N-6 O N-3, EN PARTICULAR, ACIDO GAMMA-LINOLENICO, ACIDO DIHOMO-GAMMA-LINOLENICO O ACIDO EICOSAPENTAENOICO, Y COMPUESTOS DE HIERRO ASIMILABLE EN UNA FORMA DE UNIDAD DE DOSIS, OPCIONALMENTE CON UN DILUYENTE O VEHICULO, ESTANDO DICHOS ACIDOS PRESENTES COMO TALES O COMO DERIVADOS CONVERTIBLES EN ELLOS DENTRO DEL ORGANISMO, Y SIENDO LAS CANTIDADES DE DICHOS ACIDOS O DERIVADOS DE 1 MG A 100 G (CALCULADOS COMO ACIDO GAMMA-LINOLENICO) Y DE DICHOS COMPUESTOS DE HIERRO DE 0,1 MG A 10 G (CALCULADO COMO HIERRO) O SUBMULTIPLOS DE DICHAS CANTIDADES CONVNIENTES PARA SU ADMINISTRACION DIARIA.
ES198787302323T 1986-03-21 1987-03-18 Una composicion a base de hierro y metodo para el tratamiento del cancer. Expired - Lifetime ES2033831T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868607137A GB8607137D0 (en) 1986-03-21 1986-03-21 Compositions

Publications (1)

Publication Number Publication Date
ES2033831T3 true ES2033831T3 (es) 1993-04-01

Family

ID=10595060

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787302323T Expired - Lifetime ES2033831T3 (es) 1986-03-21 1987-03-18 Una composicion a base de hierro y metodo para el tratamiento del cancer.

Country Status (12)

Country Link
US (1) US5128152A (es)
EP (1) EP0246734B1 (es)
JP (1) JP2574153B2 (es)
AT (1) ATE60508T1 (es)
AU (1) AU595012B2 (es)
CA (1) CA1287297C (es)
DE (1) DE3767763D1 (es)
ES (1) ES2033831T3 (es)
GB (1) GB8607137D0 (es)
GR (1) GR3001473T3 (es)
IE (1) IE59635B1 (es)
ZA (1) ZA871788B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5246726A (en) * 1986-03-21 1993-09-21 Efamol Ltd. Iron-containing composition and method for treatment of cancer
US5665874A (en) * 1989-01-17 1997-09-09 John Hopkins University Cancer related antigen
US5759837A (en) * 1989-01-17 1998-06-02 John Hopkins University Chemotherapy for cancer by inhibiting the fatty acid biosynthetic pathway
US5759791A (en) * 1989-01-17 1998-06-02 The Johns Hopkins University Cancer related antigen
US5264217A (en) * 1990-01-30 1993-11-23 Efamol Holdings Ltd. Method of increasing the total fat content of milk
EP0447569B1 (en) * 1990-03-13 1994-10-05 Jara Ores Riha Product for the prophylaxis, diagnosis and therapy of rheumatic, autoimmune, skin and connective tissue diseases of an unknown aetiology, and methods of its manufacture and use
NO168152L (no) * 1990-05-23 1991-10-14 Norsk Hydro As Fiskefôr
GB2254556B (en) * 1991-04-11 1995-04-12 Fisons Plc Formulations containing linolenic acid
JPH07509470A (ja) * 1992-07-24 1995-10-19 ザ・ジョーンズ・ホプキンス・ユニバーシティ がんの治療に脂肪酸合成阻害剤を用いる方法
US5614551A (en) * 1994-01-24 1997-03-25 The Johns Hopkins University Inhibitors of fatty acid synthesis as antimicrobial agents
DE4419256A1 (de) * 1994-06-01 1995-12-07 Rau Freiherr Von Nagell Helmut Verwendung von intravenös applizierbarem Eisen zur Therapie von Tumorerkrankungen und/oder Infektionskrankheiten
US5981575A (en) * 1996-11-15 1999-11-09 Johns Hopkins University, The Inhibition of fatty acid synthase as a means to reduce adipocyte mass
AU2001272908A1 (en) 2000-05-10 2001-11-20 David A. Sirbasku Compositions and methods for the diagnosis, treatment and prevention of steroid hormone responsive cancers
US20030072812A1 (en) 2001-05-10 2003-04-17 Sirbasku David A Breast cancer eradication program
EP2299265A1 (en) * 2001-11-13 2011-03-23 Signe BioPharma Inc. Cancer eradication program
CA2436650A1 (en) * 2003-08-06 2005-02-06 Naturia Inc. Conjugated linolenic acid (clnatm) compositions: synthesis, purification and uses

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3911117A (en) * 1971-12-20 1975-10-07 Fredrik Ender Raw fish and iron chelated with glutamic or ribonucleic acid in a mink diet
EP0004770B1 (en) * 1978-04-11 1984-06-13 Efamol Limited Pharmaceutical and dietary composition comprising gamma-linolenic acids
ATE24266T1 (de) * 1982-04-16 1987-01-15 Nestle Sa Lipidhaltige zusammensetzung fuer die orale, enterale oder parenterale ernaehrung.
GB8302708D0 (en) * 1983-02-01 1983-03-02 Efamol Ltd Pharmaceutical and dietary composition
US4526902A (en) * 1983-10-24 1985-07-02 Century Laboratories, Inc. Combined fatty acid composition for treatment or prophylaxis of thrombo-embolic conditions
US4745099A (en) * 1985-02-06 1988-05-17 Chugai Seiyaku Kabushiki Kaisha Pharmaceutical composition for the treatment of the anemia of malignant tumors

Also Published As

Publication number Publication date
IE59635B1 (en) 1994-03-09
JP2574153B2 (ja) 1997-01-22
ZA871788B (en) 1987-10-28
DE3767763D1 (de) 1991-03-07
EP0246734A1 (en) 1987-11-25
AU7018187A (en) 1987-09-24
IE870638L (en) 1987-09-21
AU595012B2 (en) 1990-03-22
US5128152A (en) 1992-07-07
ATE60508T1 (de) 1991-02-15
GR3001473T3 (en) 1992-10-08
EP0246734B1 (en) 1991-01-30
GB8607137D0 (en) 1986-04-30
CA1287297C (en) 1991-08-06
JPS62226923A (ja) 1987-10-05

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