ES2034239T3 - Purificacion de gm-csf. - Google Patents

Purificacion de gm-csf.

Info

Publication number
ES2034239T3
ES2034239T3 ES198888306421T ES88306421T ES2034239T3 ES 2034239 T3 ES2034239 T3 ES 2034239T3 ES 198888306421 T ES198888306421 T ES 198888306421T ES 88306421 T ES88306421 T ES 88306421T ES 2034239 T3 ES2034239 T3 ES 2034239T3
Authority
ES
Spain
Prior art keywords
csf
csf purification
purification
macrophago
coloniestimulating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888306421T
Other languages
English (en)
Inventor
Paul P. Trotta
Paul Reichert
Gail F. Seelig
Robert A. Kosecki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp & Dohme LLC
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ES2034239T3 publication Critical patent/ES2034239T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Detergent Compositions (AREA)
  • Amplifiers (AREA)

Abstract

SE DESRIBE UN METODO PARA PURIFICAR EL FACTOR COLONIESTIMULANTE DE MACROFAGO DE GRANULOCITO (GM-CSF), EN PARTICULAR GM-CSF HUMANO, QUE COMPRENDE, SUCESIVAMENTE, CAMBIO IONICO, AFINIDAD COLORANTE-LIGANDO, FILTRACION POR GEL Y CROMATOGRAFIA DE FASE INVERTIDA.
ES198888306421T 1987-07-16 1988-07-13 Purificacion de gm-csf. Expired - Lifetime ES2034239T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7441087A 1987-07-16 1987-07-16

Publications (1)

Publication Number Publication Date
ES2034239T3 true ES2034239T3 (es) 1993-04-01

Family

ID=22119421

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888306421T Expired - Lifetime ES2034239T3 (es) 1987-07-16 1988-07-13 Purificacion de gm-csf.

Country Status (16)

Country Link
EP (2) EP0368904A1 (es)
JP (1) JPH0779709B2 (es)
KR (1) KR930007430B1 (es)
AT (1) ATE79884T1 (es)
AU (1) AU632460B2 (es)
DE (1) DE3874034T2 (es)
DK (1) DK11290A (es)
ES (1) ES2034239T3 (es)
GR (1) GR3006267T3 (es)
HK (1) HK182095A (es)
IE (1) IE63323B1 (es)
IL (1) IL87123A0 (es)
MY (1) MY103539A (es)
NZ (1) NZ225410A (es)
WO (1) WO1989000579A1 (es)
ZA (1) ZA885100B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03503897A (ja) * 1988-04-21 1991-08-29 メドベット・サイエンス・プロプライアテリー・リミテッド ひとｇｍ‐ｃｓｆ変異形類
KR100406019B1 (ko) * 1998-09-30 2004-03-20 주식회사유한양행 겔여과컬럼크로마토그래피를이용한봉입체형태의인체과립성백혈구콜로니자극인자의재생방법
US7598356B2 (en) 2004-07-08 2009-10-06 Board of Regents of the University of Nebraska by and on behalf of the University of Nebraska Medical Center Method for purifying a protein of the cystine-knot superfamily
EP3116891B1 (en) * 2014-03-10 2020-02-12 Richter Gedeon Nyrt. Immunoglobulin purification using pre-cleaning steps
WO2025259466A1 (en) 2024-06-13 2025-12-18 University Of Rochester Gm-csf and gm-csf-induced dendritic cells enhance fracture healing and bone repair

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS617296A (ja) * 1984-06-19 1986-01-13 イミユネツクス、コ−ポレ−シヨン インタ−ロイキン１の遺伝子の精製、クロ−ニング及び特性づけ
ES8701226A1 (es) * 1984-07-06 1986-11-16 Sandoz Ag Procedimiento de obtencion de una proteina de factor estimu-lante de colonias (csf) en primates
JPS61124392A (ja) * 1984-11-22 1986-06-12 Asahi Chem Ind Co Ltd 遺伝子組換体の産生する生理活性物質の精製法
EP0215126B1 (en) * 1985-02-08 1991-07-31 Chugai Seiyaku Kabushiki Kaisha Human granulocyte colony stimulating factor
JPS62153752A (ja) * 1985-12-27 1987-07-08 Showa Denko Kk クロマトグラフイ−用吸着担体

Also Published As

Publication number Publication date
DK11290D0 (da) 1990-01-15
HK182095A (en) 1995-12-08
DK11290A (da) 1990-01-15
KR890701617A (ko) 1989-12-21
MY103539A (en) 1993-07-31
IL87123A0 (en) 1988-12-30
ZA885100B (en) 1989-01-16
JPH02502640A (ja) 1990-08-23
ATE79884T1 (de) 1992-09-15
DE3874034D1 (de) 1992-10-01
KR930007430B1 (ko) 1993-08-10
NZ225410A (en) 1990-09-26
WO1989000579A1 (en) 1989-01-26
IE882146L (en) 1989-01-16
GR3006267T3 (es) 1993-06-21
EP0368904A1 (en) 1990-05-23
JPH0779709B2 (ja) 1995-08-30
EP0299746A1 (en) 1989-01-18
DE3874034T2 (de) 1993-01-07
EP0299746B1 (en) 1992-08-26
AU2085188A (en) 1989-02-13
AU632460B2 (en) 1993-01-07
IE63323B1 (en) 1995-04-05

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