ES2035156T3 - Un metodo y un dispositivo para el ensayo acustico no invasivo de elasticidad de tejidos biologicos blandos. - Google Patents
Un metodo y un dispositivo para el ensayo acustico no invasivo de elasticidad de tejidos biologicos blandos.Info
- Publication number
- ES2035156T3 ES2035156T3 ES8888108905T ES88108905T ES2035156T3 ES 2035156 T3 ES2035156 T3 ES 2035156T3 ES 8888108905 T ES8888108905 T ES 8888108905T ES 88108905 T ES88108905 T ES 88108905T ES 2035156 T3 ES2035156 T3 ES 2035156T3
- Authority
- ES
- Spain
- Prior art keywords
- probe
- speed
- elasticity
- biological tissues
- soft biological
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0048—Detecting, measuring or recording by applying mechanical forces or stimuli
- A61B5/0051—Detecting, measuring or recording by applying mechanical forces or stimuli by applying vibrations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0048—Detecting, measuring or recording by applying mechanical forces or stimuli
- A61B5/0053—Detecting, measuring or recording by applying mechanical forces or stimuli by applying pressure, e.g. compression, indentation, palpation, grasping, gauging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0048—Detecting, measuring or recording by applying mechanical forces or stimuli
- A61B5/0057—Detecting, measuring or recording by applying mechanical forces or stimuli by applying motion other than vibrations, e.g. rolling, rubbing, applying a torque, tribometry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/44—Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
- A61B5/441—Skin evaluation, e.g. for skin disorder diagnosis
- A61B5/442—Evaluating skin mechanical properties, e.g. elasticity, hardness, texture, wrinkle assessment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/48—Diagnostic techniques
- A61B8/485—Diagnostic techniques involving measuring strain or elastic properties
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N29/00—Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N29/00—Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
- G01N29/04—Analysing solids
- G01N29/07—Analysing solids by measuring propagation velocity or propagation time of acoustic waves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/45—For evaluating or diagnosing the musculoskeletal system or teeth
- A61B5/4519—Muscles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2291/00—Indexing codes associated with group G01N29/00
- G01N2291/02—Indexing codes associated with the analysed material
- G01N2291/028—Material parameters
- G01N2291/02827—Elastic parameters, strength or force
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2291/00—Indexing codes associated with group G01N29/00
- G01N2291/04—Wave modes and trajectories
- G01N2291/044—Internal reflections (echoes), e.g. on walls or defects
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Surgery (AREA)
- Biophysics (AREA)
- Medical Informatics (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Acoustics & Sound (AREA)
- Radiology & Medical Imaging (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
Abstract
ESTA INVENCION PROVEE EL EXAMEN NO INVASIVO DE LA ELASTICIDAD DE TEJIDOS BIOLOGICOS BLANDOS PARA EL DIAGNOSTICO DEL ESTADO FISIOLOGICO Y PATOLOGICO EN HUMENOAS Y ANIMALES, POR EXCITACION DE LAS DEFORMACIONES TANGENCIALES OSCILATORIAS SOBRE LA SUPERFICIE DEL TEJIDO EN EL INTERVALO DE FRECUENCIA DE 0.5 - 30 HZ Y POR DETERMINACION DE LA VELOCIDAD DE LA ONDA DE SUPERFICIE EXCITADA QUE SE PROPAGA A LO LARGO DEL VECTOR DE DESPLAZAMIENTO INICIAL. EL DISPOSITIVO QUE PROVEE LA APLICACION DE ESTE METODO INCLUYE UNA SONDA CON UNA TRANSMICION Y DOS PIEZOTRANSDUCTORES DE RECEPCION EQUIPADOS CON BOQUILLAS DE CONTACTO Y MONTADOS EN EL CUERPO DE LA SONDA POR MEDIO DE LOS MANGOS ALARGADOS QUE SIRVEN COMO LINEAS DE RETARDO ACUSTICO Y LOS MEDIOS ELECTRONICOS QUE FORMAN IMPULSOS PARA EXCITAR EL TRANSDUCTOR, REALIZAR EL PROCESAMIENTO DE LAS SEÑALES ACUSTICAS RECIBIDAS, MEDIR EL TIEMPO DE VUELO DE ACUSTICAS IMPULSA DESDE EL TRANSMISOR AL RECEPTOR, LO TRANSFORMA EN LA VELOCIDAD DE SONIDO Y EXPONE EL VALOR DE LA VELOCIDAD. EL DISPOSITIVO TIENE TAMBIEN LA FACILIDAD PARA NORMALIZAR LA FUERZA POR LA CUAL, LA SONDA ES EMBUTIDA EN UN TEJIDO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| YU32588A YU47190B (sh) | 1988-02-19 | 1988-02-19 | Uredjaj za neinvazivno akustičko ispitivanje elastičnosti mekih bioloških materijala |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2035156T3 true ES2035156T3 (es) | 1993-04-16 |
Family
ID=25549387
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES8888108905T Expired - Lifetime ES2035156T3 (es) | 1988-02-19 | 1988-06-03 | Un metodo y un dispositivo para el ensayo acustico no invasivo de elasticidad de tejidos biologicos blandos. |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US4947851A (es) |
| EP (1) | EP0329817B1 (es) |
| JP (1) | JPH0221840A (es) |
| KR (1) | KR920006032B1 (es) |
| CN (1) | CN1023442C (es) |
| AR (1) | AR242898A1 (es) |
| AT (1) | ATE79473T1 (es) |
| AU (1) | AU621341B2 (es) |
| BR (1) | BR8900698A (es) |
| CA (1) | CA1318018C (es) |
| DD (1) | DD283560A5 (es) |
| DE (1) | DE3873742T2 (es) |
| DK (1) | DK75389A (es) |
| ES (1) | ES2035156T3 (es) |
| FI (1) | FI886048A7 (es) |
| GR (1) | GR3006246T3 (es) |
| HU (1) | HU202650B (es) |
| IE (1) | IE890137L (es) |
| IL (1) | IL88691A (es) |
| IS (1) | IS1488B (es) |
| NO (1) | NO890496L (es) |
| NZ (1) | NZ227893A (es) |
| PL (1) | PL277821A1 (es) |
| PT (1) | PT89735B (es) |
| TR (1) | TR24539A (es) |
| YU (1) | YU47190B (es) |
Families Citing this family (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5115808A (en) * | 1988-02-19 | 1992-05-26 | Institute Of General And Physical Chemistry | Method and device for noninvasive acoustic testing of elasticity of soft biological tissues |
| DE3832690C1 (es) * | 1988-09-26 | 1990-04-12 | Courage + Khazaka Electronic Gmbh, 5000 Koeln, De | |
| US5293870A (en) * | 1989-11-17 | 1994-03-15 | Board Of Regents The University Of Texas System | Method and apparatus for elastographic measurement and imaging |
| US5107837A (en) * | 1989-11-17 | 1992-04-28 | Board Of Regents, University Of Texas | Method and apparatus for measurement and imaging of tissue compressibility or compliance |
| US5426979A (en) * | 1990-06-04 | 1995-06-27 | Medicano Systems Ltd. | Frequency spectrum apparatus for determining mechanical properties |
| AU660034B2 (en) * | 1991-05-10 | 1995-06-08 | Board Of Regents, The University Of Texas System | Method for elastographic measurement and imaging |
| US5524636A (en) * | 1992-12-21 | 1996-06-11 | Artann Corporation Dba Artann Laboratories | Method and apparatus for elasticity imaging |
| US5265612A (en) * | 1992-12-21 | 1993-11-30 | Medical Biophysics International | Intracavity ultrasonic device for elasticity imaging |
| US5922018A (en) * | 1992-12-21 | 1999-07-13 | Artann Corporation | Method for using a transrectal probe to mechanically image the prostate gland |
| US6142959A (en) * | 1992-12-21 | 2000-11-07 | Armed L.L.C. | Device for palpation and mechanical imaging of the prostate |
| US5785663A (en) * | 1992-12-21 | 1998-07-28 | Artann Corporation | Method and device for mechanical imaging of prostate |
| US5860934A (en) * | 1992-12-21 | 1999-01-19 | Artann Corporation | Method and device for mechanical imaging of breast |
| US5836876A (en) * | 1993-03-03 | 1998-11-17 | Washington University | Method and apparatus for determining bone density and diagnosing osteoporosis |
| JPH08201490A (ja) * | 1995-01-31 | 1996-08-09 | Mitsumi Electric Co Ltd | センサic |
| CA2233022A1 (en) * | 1995-09-27 | 1997-04-03 | Artann Laboratories | Measuring anisotropic mechanical properties of tissue |
| US5810731A (en) * | 1995-11-13 | 1998-09-22 | Artann Laboratories | Method and apparatus for elasticity imaging using remotely induced shear wave |
| US5606971A (en) * | 1995-11-13 | 1997-03-04 | Artann Corporation, A Nj Corp. | Method and device for shear wave elasticity imaging |
| IL116784A (en) | 1996-01-16 | 2000-01-31 | Hadasit Med Res Service | Device for examining viscoelasticity of a living or artificial tissue |
| US5911694A (en) * | 1996-08-22 | 1999-06-15 | Olympus Optical Co., Ltd. | Endoceliac physical quantity measuring apparatus having excellent measuring resolution |
| EP0967916B1 (en) * | 1996-12-06 | 2005-09-14 | Jocelyn W. Cowie | Method and apparatus for locating soft tissue lesions |
| ZA985834B (en) * | 1997-07-21 | 1999-01-14 | Henkel Corp | Method for reinforcing structural members |
| US6364849B1 (en) | 1999-05-03 | 2002-04-02 | Access Wellness And Physical Therapy | Soft tissue diagnostic apparatus and method |
| WO2001080742A1 (en) * | 2000-04-26 | 2001-11-01 | Koninklijke Philips Electronics N.V. | Ultrasonic method and system for shear wave parameter estimation |
| DE50010517D1 (de) * | 2000-06-21 | 2005-07-14 | Courage Brewing Ltd | Messgerät zur Messung der elastischen Eigenschaften einer Oberflächenstruktur |
| JP3725515B2 (ja) * | 2000-08-23 | 2005-12-14 | 三菱電機株式会社 | 非破壊検査装置 |
| CA2333224A1 (en) | 2001-01-31 | 2002-07-31 | University Technologies International Inc. | Non-invasive diagnostic method and apparatus for musculoskeletal systems |
| US6569108B2 (en) | 2001-03-28 | 2003-05-27 | Profile, Llc | Real time mechanical imaging of the prostate |
| US6923065B2 (en) * | 2001-09-17 | 2005-08-02 | Thyssen Elevator Capital Corp. | Apparatus for testing aramid fiber elevator cables |
| US6662660B2 (en) * | 2001-09-17 | 2003-12-16 | Thyssen Elevator Capital Corp. | Apparatus for testing aramid fiber elevator cables |
| ITMI20030568A1 (it) * | 2003-03-21 | 2004-09-22 | Derming S R L | Strumento di misura delle proprieta' meccaniche della pelle e metodo di valutazione dell'efficacia di trattamenti estetici e/o prodotti cosmetici e farmaceutici sulla pelle |
| JP4443957B2 (ja) * | 2003-04-28 | 2010-03-31 | 株式会社根本杏林堂 | 漏出検出装置および方法 |
| US7611465B2 (en) * | 2003-07-15 | 2009-11-03 | Board Of Regents, The University Of Texas System | Rapid and accurate detection of bone quality using ultrasound critical angle reflectometry |
| DE112004001625T5 (de) * | 2003-09-05 | 2006-06-22 | William Marsh Rice University, Houston | Nichtinvasive Gewebebeurteilung |
| CA2551957A1 (en) | 2003-12-30 | 2005-08-18 | 3M Innovative Properties Company | Acousto-mechanical detection systems and methods of use |
| US20060052719A1 (en) * | 2004-09-09 | 2006-03-09 | Eduardo Ruvolo | Method of measuring of skin anisotropy |
| JP4762147B2 (ja) * | 2004-09-14 | 2011-08-31 | 株式会社根本杏林堂 | 漏出検出装置 |
| CN1873406B (zh) * | 2006-06-30 | 2011-02-16 | 王岩松 | 声学材料性能综合测试仪 |
| US20080125653A1 (en) * | 2006-11-27 | 2008-05-29 | Board Of Regents, The University Of Texas System | Density and porosity measurements by ultrasound |
| US8175689B2 (en) * | 2007-03-19 | 2012-05-08 | Nicholas Hunter-Jones | Skin elasticity measurement |
| EP2146640B1 (en) * | 2007-05-16 | 2018-05-23 | Super Sonic Imagine | Method and device for measuring a mean value of visco-elasticity of a region of interest |
| US9044192B2 (en) * | 2008-04-07 | 2015-06-02 | Mayo Foundation For Medical Education And Research | System and method for non-invasively measuring tissue viscoelasticity using surface waves |
| US8700123B2 (en) | 2008-10-20 | 2014-04-15 | The Johns Hopkins University | Environment property estimaton and graphical display |
| US8147410B2 (en) * | 2009-03-23 | 2012-04-03 | The Hong Kong Polytechnic University | Method and apparatus for ultrasound imaging and elasticity measurement |
| US8052622B2 (en) * | 2009-09-02 | 2011-11-08 | Artann Laboratories Inc | Methods for characterizing vaginal tissue elasticity |
| US8187208B2 (en) * | 2009-09-02 | 2012-05-29 | Artann Laboratories Inc. | Methods for assessment of pelvic organ conditions affecting the vagina |
| US9681923B2 (en) | 2009-09-15 | 2017-06-20 | Koninklijke Philips N.V. | Medical ultrasound device with force detection |
| NO336532B1 (no) * | 2011-01-12 | 2015-09-21 | Mecsense As | Sensor for måling av densiteten av et kroppsfluid og/eller motstanden til en membran |
| US9031701B2 (en) | 2011-02-15 | 2015-05-12 | Hemosonics Llc | Characterization of blood hemostasis and oxygen transport parameters |
| JP5491671B2 (ja) * | 2013-11-22 | 2014-05-14 | スーパー ソニック イマジン | 関心領域の粘弾性の平均値を測定するための方法 |
| AT514566B1 (de) | 2013-12-04 | 2015-02-15 | Mkw Electronics Gmbh | Verfahren und Vorrichtung für die Untersuchung von Tierhufen bzw. Tierklauen |
| FR3016791B1 (fr) * | 2014-01-30 | 2019-09-20 | Centre National De La Recherche Scientifique - Cnrs | Procede et dispositif de caracterisation de la peau |
| EP3256844B1 (en) * | 2015-02-09 | 2021-04-14 | Ventana Medical Systems, Inc. | System and method for standardizing diffusion of a fluid into tissues |
| US9726647B2 (en) | 2015-03-17 | 2017-08-08 | Hemosonics, Llc | Determining mechanical properties via ultrasound-induced resonance |
| TWI580960B (zh) * | 2015-05-08 | 2017-05-01 | 國立臺灣大學 | 彈性分布影像生成系統 |
| CN105300812B (zh) * | 2015-10-26 | 2017-11-28 | 苏州大学 | 生物软组织力学特性测试仪及生物软组织的力学测试方法 |
| CN106264605B (zh) * | 2016-08-04 | 2020-10-09 | 无锡海斯凯尔医学技术有限公司 | 超声装置及产生机械振动的装置 |
| CN106680369B (zh) * | 2017-02-23 | 2024-02-09 | 天健创新(北京)监测仪表股份有限公司 | 一种超声波泥水界面测量装置及方法 |
| AR113330A1 (es) * | 2017-10-31 | 2020-04-08 | Univ La Republica | Equipo y método para determinar la elasticidad de sólidos blandos |
| US12484837B2 (en) | 2018-05-11 | 2025-12-02 | Carruthers Instruments Inc. | Skin torsionometer |
| CN113229841B (zh) * | 2021-04-26 | 2022-08-02 | 中南大学湘雅三医院 | 一种医用声音、振动采集分析系统与方法 |
| CN117017340A (zh) * | 2023-05-30 | 2023-11-10 | 无锡海斯凯尔医学技术有限公司 | 基于剪切波的弹性成像系统 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3783679A (en) * | 1971-02-22 | 1974-01-08 | Walter A Gunkel | Time base measurement circuit |
| US4175546A (en) * | 1977-09-06 | 1979-11-27 | Ahron P. Leichtman | Device for measuring sensitivity to vibration |
| DE2741338A1 (de) * | 1977-09-14 | 1979-03-22 | Industrie Automation Gmbh & Co | Einrichtung zur bestimmung der mechanischen eigenfrequenz von blutgefaessen, sehnen, knochen oder aehnlichen organen in einem koerper |
| IL54277A0 (en) * | 1978-03-14 | 1978-06-15 | Yissum Res Dev Co | Measurement of elasticity |
| US4250894A (en) * | 1978-11-14 | 1981-02-17 | Yeda Research & Development Co., Ltd. | Instrument for viscoelastic measurement |
| DE3242284A1 (de) * | 1982-11-16 | 1984-05-17 | Philips Patentverwaltung Gmbh, 2000 Hamburg | Verfahren und anordnung zur laufzeitbestimmung eines ultraschallimpulses |
| US4522071A (en) * | 1983-07-28 | 1985-06-11 | The United States Of America As Represented By The United States Department Of Energy | Method and apparatus for measuring stress |
| EP0181131A3 (en) * | 1984-11-01 | 1987-05-20 | Kent Scientific and Industrial Projects Limited | Apparatus for detecting the resonant frequency of a bone |
| US4777599A (en) * | 1985-02-26 | 1988-10-11 | Gillette Company | Viscoelastometry of skin using shear wave propagation |
| SU1357827A1 (ru) * | 1985-10-23 | 1987-12-07 | Куйбышевский политехнический институт им.В.В.Куйбышева | Способ измерени скорости и затухани продольных упругих волн |
| CA1264196A (en) * | 1986-07-18 | 1990-01-02 | Canadian Patents And Development Limited/Societe Canadienne Des Brevets Et D'exploitation Limitee | Method of, and an apparatus for, evaluating forming capabilities of solid plate |
| US4768379A (en) * | 1986-07-25 | 1988-09-06 | Grumman Aerospace Corporation | Method and apparatus for determining flow resistance of fully assembled acoustic liners |
-
1988
- 1988-02-19 YU YU32588A patent/YU47190B/sh unknown
- 1988-06-03 ES ES8888108905T patent/ES2035156T3/es not_active Expired - Lifetime
- 1988-06-03 AT AT88108905T patent/ATE79473T1/de active
- 1988-06-03 EP EP88108905A patent/EP0329817B1/en not_active Expired - Lifetime
- 1988-06-03 DE DE8888108905T patent/DE3873742T2/de not_active Expired - Fee Related
- 1988-08-18 US US07/234,330 patent/US4947851A/en not_active Expired - Fee Related
- 1988-12-15 IL IL88691A patent/IL88691A/xx not_active IP Right Cessation
- 1988-12-21 CA CA000586645A patent/CA1318018C/en not_active Expired - Fee Related
- 1988-12-21 IS IS3423A patent/IS1488B/is unknown
- 1988-12-30 FI FI886048A patent/FI886048A7/fi not_active Application Discontinuation
-
1989
- 1989-01-18 IE IE890137A patent/IE890137L/xx unknown
- 1989-01-18 AR AR89313010A patent/AR242898A1/es active
- 1989-02-07 NO NO89890496A patent/NO890496L/no unknown
- 1989-02-08 NZ NZ227893A patent/NZ227893A/xx unknown
- 1989-02-10 JP JP1032554A patent/JPH0221840A/ja active Pending
- 1989-02-15 AU AU30000/89A patent/AU621341B2/en not_active Ceased
- 1989-02-16 PT PT89735A patent/PT89735B/pt not_active IP Right Cessation
- 1989-02-17 DD DD89325845A patent/DD283560A5/de not_active IP Right Cessation
- 1989-02-17 BR BR898900698A patent/BR8900698A/pt not_active IP Right Cessation
- 1989-02-17 DK DK075389A patent/DK75389A/da not_active Application Discontinuation
- 1989-02-17 TR TR89/0167A patent/TR24539A/xx unknown
- 1989-02-17 HU HU89805A patent/HU202650B/hu not_active IP Right Cessation
- 1989-02-18 CN CN89100841A patent/CN1023442C/zh not_active Expired - Fee Related
- 1989-02-18 KR KR8901927A patent/KR920006032B1/ko not_active Expired
- 1989-02-20 PL PL27782189A patent/PL277821A1/xx unknown
-
1992
- 1992-11-13 GR GR920401650T patent/GR3006246T3/el unknown
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