ES2036566T3 - Solucion conteniendo cloruro de lisocima y gliciricinato dipotasico. - Google Patents
Solucion conteniendo cloruro de lisocima y gliciricinato dipotasico.Info
- Publication number
- ES2036566T3 ES2036566T3 ES198787118175T ES87118175T ES2036566T3 ES 2036566 T3 ES2036566 T3 ES 2036566T3 ES 198787118175 T ES198787118175 T ES 198787118175T ES 87118175 T ES87118175 T ES 87118175T ES 2036566 T3 ES2036566 T3 ES 2036566T3
- Authority
- ES
- Spain
- Prior art keywords
- chloride
- lysocima
- glycricinate
- dipotasic
- sodium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 title 1
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 abstract 2
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 abstract 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 abstract 2
- LWIHDJKSTIGBAC-UHFFFAOYSA-K tripotassium phosphate Chemical compound [K+].[K+].[K+].[O-]P([O-])([O-])=O LWIHDJKSTIGBAC-UHFFFAOYSA-K 0.000 abstract 2
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 abstract 1
- BIVBRWYINDPWKA-VLQRKCJKSA-L Glycyrrhizinate dipotassium Chemical compound [K+].[K+].O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@H]1CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@](C)(CC[C@@]5(CC[C@@]4(C)[C@]3(C)CC[C@H]2C1(C)C)C)C(O)=O)C([O-])=O)[C@@H]1O[C@H](C([O-])=O)[C@@H](O)[C@H](O)[C@H]1O BIVBRWYINDPWKA-VLQRKCJKSA-L 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000001110 calcium chloride Substances 0.000 abstract 1
- 229910001628 calcium chloride Inorganic materials 0.000 abstract 1
- 229940101029 dipotassium glycyrrhizinate Drugs 0.000 abstract 1
- 239000003889 eye drop Substances 0.000 abstract 1
- 229940012356 eye drops Drugs 0.000 abstract 1
- 229940073475 lysozyme hydrochloride Drugs 0.000 abstract 1
- 229910001629 magnesium chloride Inorganic materials 0.000 abstract 1
- 229910000027 potassium carbonate Inorganic materials 0.000 abstract 1
- 239000001103 potassium chloride Substances 0.000 abstract 1
- 235000011164 potassium chloride Nutrition 0.000 abstract 1
- 239000001508 potassium citrate Substances 0.000 abstract 1
- 229960002635 potassium citrate Drugs 0.000 abstract 1
- QEEAPRPFLLJWCF-UHFFFAOYSA-K potassium citrate (anhydrous) Chemical compound [K+].[K+].[K+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O QEEAPRPFLLJWCF-UHFFFAOYSA-K 0.000 abstract 1
- 235000011082 potassium citrates Nutrition 0.000 abstract 1
- 229910000160 potassium phosphate Inorganic materials 0.000 abstract 1
- 235000011009 potassium phosphates Nutrition 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- 239000001509 sodium citrate Substances 0.000 abstract 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 abstract 1
- 239000001488 sodium phosphate Substances 0.000 abstract 1
- 229910000162 sodium phosphate Inorganic materials 0.000 abstract 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Dermatology (AREA)
- Ophthalmology & Optometry (AREA)
- Inorganic Chemistry (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cosmetics (AREA)
- Peptides Or Proteins (AREA)
Abstract
SOLUCION ACUOSA QUE CONTIENE HIDROCLORURO DE LISOZIMA, GLICIRRICINATO DIPOTASICO, POR LO MENOS UN COMPUESTO SELECCIONADO DEL GRUPO FORMADO POR CLORURO SODICO, CLORURO POTASICO, CLORURO CALCICO, CLORURO MAGNESICO, FOSFATO SODICO, FOSFATO POTASICO, CITRATO SODICO, CITRATO POTASICO, CARBONATO SODICO Y CARBONATO POTASICO, Y AGUA, TIENE UN PH DE 5 A 9 Y ES UTIL PARA EMPLEO EN GOTAS PARA LOS OJOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61303163A JPH085800B2 (ja) | 1986-12-19 | 1986-12-19 | 塩化リゾチ−ム及びグリチルリチン酸ジカリウム含有水溶液製剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2036566T3 true ES2036566T3 (es) | 1993-06-01 |
Family
ID=17917640
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES198787118175T Expired - Lifetime ES2036566T3 (es) | 1986-12-19 | 1987-12-08 | Solucion conteniendo cloruro de lisocima y gliciricinato dipotasico. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4961927A (es) |
| EP (1) | EP0275457B1 (es) |
| JP (1) | JPH085800B2 (es) |
| KR (1) | KR910005885B1 (es) |
| AT (1) | ATE73670T1 (es) |
| DE (1) | DE3777611D1 (es) |
| ES (1) | ES2036566T3 (es) |
| GR (1) | GR3004119T3 (es) |
| PH (1) | PH24628A (es) |
| PT (1) | PT86400B (es) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2212062B (en) * | 1987-11-13 | 1991-07-17 | Isf Spa | Pharmaceutical compositions containing a calcitonin and a glycyrrhizinate ab- sorption enhancer |
| JP2700465B2 (ja) * | 1988-05-09 | 1998-01-21 | 関西酵素株式会社 | 塩化リゾチーム配合トイレタリー製品 |
| IT8920486A0 (it) * | 1989-05-12 | 1989-05-12 | Isf Spa | Composizioni farmaceutiche. |
| JPH06199648A (ja) * | 1993-01-08 | 1994-07-19 | Kao Corp | 可溶化型化粧料 |
| US5482710A (en) * | 1993-07-30 | 1996-01-09 | Chesebrough-Pond'usa Co., Division Of Conopco, Inc. | Cosmetic composition for treatment of pimples and redness |
| CA2232855C (en) * | 1997-04-10 | 2007-10-09 | Roche Consumer Health (Worldwide) Sa | Pharmaceutical formulation |
| IT1291366B1 (it) * | 1997-05-14 | 1999-01-07 | Angelini Ricerche Spa | Composizione farmaceutica antivirale comprendente acido glicirrizico ed almeno una proteina dotata di attivita' antivirale |
| US6649176B1 (en) | 2000-06-29 | 2003-11-18 | Johnson & Johnson Consumer Companies, Inc. | Compositions containing mineral water |
| US6432424B1 (en) | 2000-06-29 | 2002-08-13 | Johnson & Johnson Consumer Companies, Inc. | Cosmetic compositions containing creatine, carnitine, and/or pyruvic acid |
| US6372791B1 (en) | 2000-06-29 | 2002-04-16 | Johnson & Johnson Consumer Companies, Inc. | Method of promoting skin cell metabolism |
| US6630175B1 (en) * | 2000-06-29 | 2003-10-07 | Johnson & Johnson Consumer Companies, Inc. | Method of reducing eye irritation |
| US7678389B1 (en) * | 2004-06-16 | 2010-03-16 | Scott Cordray | Treatment of optic and otic inflammation |
| US20100080790A1 (en) * | 2005-07-13 | 2010-04-01 | University Of South Carolina | Sterilization using high-pressure carbon dioxide |
| US20070264362A1 (en) * | 2006-05-11 | 2007-11-15 | Nina Yoshpe | Method and composition for treating ear inflammation caused by dry ear |
| RU2009136422A (ru) * | 2007-03-02 | 2011-04-10 | СЕНТ СИМЕОН ЭлДиЭй (US) | Новые офтальмологические композиции, содержащие рекомбинантный человеческий лизоцим, и их применение для лечения состояний глаз и в качестве растворов для контактных линз |
| JP5274826B2 (ja) * | 2007-12-12 | 2013-08-28 | サンスター株式会社 | 口腔用組成物 |
| IT1401153B1 (it) * | 2010-07-28 | 2013-07-12 | Neova Technologies B V | Formulazioni di lisozima gelificato |
| US8758836B2 (en) | 2011-09-09 | 2014-06-24 | Nina S. YOSHPE | Method and formulation for treating dry ear inflammation with cortisone |
| WO2017209721A1 (en) | 2016-06-02 | 2017-12-07 | Alemdar Eda | A drug derived from enzymes present in the human saliva for use in preventing corneal clouding or cataract formation |
| CN109718246A (zh) * | 2019-02-19 | 2019-05-07 | 刘宝林 | 一种鼻腔清洗液 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB843135A (en) * | 1957-07-16 | 1960-08-04 | Biorex Laboratories Ltd | Glycyrrhetinic acid salts |
| US3419471A (en) * | 1965-04-19 | 1968-12-31 | Eisai Co Ltd | Preparation of albumin-free lysozyme |
| FR2037000A1 (en) * | 1969-04-30 | 1970-12-31 | Pluripharm | Non allergic lysozyme chlorhydrate prepn |
| JPS49310A (es) * | 1972-04-14 | 1974-01-05 | ||
| JPS56110609A (en) * | 1980-02-06 | 1981-09-01 | Lion Corp | Composition for oral cavity |
| GB2122893B (en) * | 1982-06-30 | 1985-06-26 | Biorex Laboratories Ltd | Glycyrrhetinic acid compositions |
| AU553789B2 (en) * | 1982-06-30 | 1986-07-24 | Biorex Laboratories Ltd. | Glycyrrhetinic acid derivatives in cream compositions |
-
1986
- 1986-12-19 JP JP61303163A patent/JPH085800B2/ja not_active Expired - Lifetime
-
1987
- 1987-11-25 US US07/125,536 patent/US4961927A/en not_active Expired - Fee Related
- 1987-12-01 KR KR1019870013602A patent/KR910005885B1/ko not_active Expired
- 1987-12-08 ES ES198787118175T patent/ES2036566T3/es not_active Expired - Lifetime
- 1987-12-08 EP EP87118175A patent/EP0275457B1/en not_active Expired - Lifetime
- 1987-12-08 AT AT87118175T patent/ATE73670T1/de not_active IP Right Cessation
- 1987-12-08 DE DE8787118175T patent/DE3777611D1/de not_active Expired - Fee Related
- 1987-12-17 PT PT86400A patent/PT86400B/pt not_active IP Right Cessation
- 1987-12-18 PH PH36270A patent/PH24628A/en unknown
-
1992
- 1992-03-23 GR GR910401867T patent/GR3004119T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPH085800B2 (ja) | 1996-01-24 |
| GR3004119T3 (es) | 1993-03-31 |
| DE3777611D1 (de) | 1992-04-23 |
| EP0275457A2 (en) | 1988-07-27 |
| PT86400A (en) | 1988-01-01 |
| JPS63156728A (ja) | 1988-06-29 |
| EP0275457B1 (en) | 1992-03-18 |
| PH24628A (en) | 1990-08-17 |
| ATE73670T1 (de) | 1992-04-15 |
| KR910005885B1 (ko) | 1991-08-06 |
| EP0275457A3 (en) | 1988-09-07 |
| KR880007059A (ko) | 1988-08-26 |
| PT86400B (pt) | 1990-11-20 |
| US4961927A (en) | 1990-10-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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