ES2036682T3 - Un procedimiento para preparar un derivado de tiofeno. - Google Patents

Un procedimiento para preparar un derivado de tiofeno.

Info

Publication number
ES2036682T3
ES2036682T3 ES198888306119T ES88306119T ES2036682T3 ES 2036682 T3 ES2036682 T3 ES 2036682T3 ES 198888306119 T ES198888306119 T ES 198888306119T ES 88306119 T ES88306119 T ES 88306119T ES 2036682 T3 ES2036682 T3 ES 2036682T3
Authority
ES
Spain
Prior art keywords
thiophene derivative
procedure
preparing
substituted
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888306119T
Other languages
English (en)
Inventor
Kimiaki Hayashi
Yasuhiko Ozaki
Kenji Yamada
Hideyuki Takenaga
Ichizo Inoue
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Pharma Corp
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Application granted granted Critical
Publication of ES2036682T3 publication Critical patent/ES2036682T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Dowels (AREA)
  • Joining Of Building Structures In Genera (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

SE DESCRIBE UN DERIVADO DE TIOFENO DE FORMULA (I), DONDE R1, R2 Y R3 SON UN GRUPO ALQUILO INFERIOR; EL ANILLO A ES UN GRUPO FENILO SUSTITUIDO O SIN SUSTITUIR; P ES UN ENTERO DE 1-3; O UNA DE SUS SALES, Y PROCEDIMIENTO PARA OBTENERLO. EL DERIVADO DE TIOFENO (I) ES UTIL COMO REGULADOR DE LA MOTILIDAD DEL TRACTO INTESTINAL.
ES198888306119T 1987-07-09 1988-07-05 Un procedimiento para preparar un derivado de tiofeno. Expired - Lifetime ES2036682T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62171669A JPS6416778A (en) 1987-07-09 1987-07-09 Thiophene derivative

Publications (1)

Publication Number Publication Date
ES2036682T3 true ES2036682T3 (es) 1993-06-01

Family

ID=15927497

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888306119T Expired - Lifetime ES2036682T3 (es) 1987-07-09 1988-07-05 Un procedimiento para preparar un derivado de tiofeno.

Country Status (15)

Country Link
US (1) US4946862A (es)
EP (1) EP0298703B1 (es)
JP (1) JPS6416778A (es)
KR (1) KR890002088A (es)
CN (1) CN1039245A (es)
AT (1) ATE61362T1 (es)
AU (1) AU600149B2 (es)
DE (1) DE3861928D1 (es)
DK (1) DK382288A (es)
ES (1) ES2036682T3 (es)
FI (1) FI882874L (es)
FR (1) FR2617842B1 (es)
GR (1) GR3001622T3 (es)
HU (1) HU202222B (es)
IL (1) IL86741A0 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2658817B1 (fr) * 1990-02-28 1993-02-05 Jouveinal Sa Ethylamines substituees, leur procede de preparation, leur utilisation comme medicament et leurs intermediaires de synthese.
FR2658822A1 (fr) * 1990-02-28 1991-08-30 Jouveinal Sa N-cycloalkylalkylamines, leur procede de preparation, leur utilisation comme medicament et leurs intermediaires de synthese.
EP0446097A1 (fr) * 1990-02-26 1991-09-11 Jouveinal S.A. Ethylamines substituées, leur procédé de préparation, leur utilisation comme médicament et leurs intermédiaires de synthèse
CA2037114C (en) * 1990-02-26 2003-09-09 Jouveinal N-cycloalkylalkylamines, their process of preparation, their use as medication and their synthetic intermediates
US5017723A (en) * 1990-02-26 1991-05-21 Jouveinal S.A. Substituted ethylamines, their preparation process, their use as medicine and their synthesising agents
IE913279A1 (en) * 1990-09-26 1992-04-08 Astra Ab (2-Thienyl)alkylamine Derivatives Having Neuroprotective¹Properties
US5362886A (en) * 1993-10-12 1994-11-08 Eli Lilly And Company Asymmetric synthesis

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3109845A (en) * 1960-02-04 1963-11-05 Thomae Gmbh Dr K 1-cyclohexyl, 1-cyclohexenyl, 1-furyl, and 1-thienyl, tertiary amino substituted methanes
FR1344455A (fr) * 1962-10-17 1963-11-29 Jouveinal Lab Amino-alcools, leurs esters et leur procédé de préparation
US4128561A (en) * 1975-12-12 1978-12-05 Parcor Process for the preparation of 2-(2-thienyl)-ethylamine and derivatives thereof
JPS5516416A (en) * 1978-07-21 1980-02-05 Hitachi Ltd Board drowing-out bar
JPS58105946A (ja) * 1981-12-18 1983-06-24 Tanabe Seiyaku Co Ltd アミノブタノ−ルエステル誘導体の製法

Also Published As

Publication number Publication date
FI882874A0 (fi) 1988-06-16
AU600149B2 (en) 1990-08-02
FR2617842B1 (fr) 1991-05-31
DE3861928D1 (de) 1991-04-11
KR890002088A (ko) 1989-04-08
US4946862A (en) 1990-08-07
DK382288A (da) 1989-01-10
JPS6416778A (en) 1989-01-20
AU1880788A (en) 1989-01-12
CN1039245A (zh) 1990-01-31
FI882874A7 (fi) 1989-01-10
EP0298703A1 (en) 1989-01-11
GR3001622T3 (en) 1992-11-23
ATE61362T1 (de) 1991-03-15
FI882874L (fi) 1989-01-10
HUT50466A (en) 1990-02-28
IL86741A0 (en) 1988-11-30
FR2617842A1 (fr) 1989-01-13
EP0298703B1 (en) 1991-03-06
HU202222B (en) 1991-02-28
DK382288D0 (da) 1988-07-08

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