ES2037254T3 - Comprimido de dihidroergotamina (d.h.e.) del tipo con matriz hidrofila y su procedimiento de fabricacion. - Google Patents

Comprimido de dihidroergotamina (d.h.e.) del tipo con matriz hidrofila y su procedimiento de fabricacion.

Info

Publication number
ES2037254T3
ES2037254T3 ES198888400340T ES88400340T ES2037254T3 ES 2037254 T3 ES2037254 T3 ES 2037254T3 ES 198888400340 T ES198888400340 T ES 198888400340T ES 88400340 T ES88400340 T ES 88400340T ES 2037254 T3 ES2037254 T3 ES 2037254T3
Authority
ES
Spain
Prior art keywords
dihydroergotamine
hydrophilic matrix
manufacturing procedure
tablet type
component
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888400340T
Other languages
English (en)
Inventor
Michel Sournac
Joel Bougaret
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Medicament SA
Original Assignee
Pierre Fabre Medicament SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre Medicament SA filed Critical Pierre Fabre Medicament SA
Application granted granted Critical
Publication of ES2037254T3 publication Critical patent/ES2037254T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A UN COMPRIMIDO DEL TIPO QUE COMPRENDE UNA DISPERSION HOMOGENEA DE UN PRINCIPIO ACTIVO A BASE DE DIHIDROERGOTAMINA (DHE) O DE UNO DE SUS DERIVADOS EN UNA MATRIZ HIDROFILA, CARACTERIZADA EN QUE DICHA MATRIZ COMPRENDE AL MENOS UN COMPONENTE HINCHANTE, Y UN COMPUESTO DILUYENTE EN LA PROPORCION HINCHANTE/DILUYENTE COMPRENDIDA ENTRE 0,2 Y 0,6 PREFERENTEMENTE 0,4. SE REFIERE IGUALMENTE L PROCEDIMIENTO DE FABRICACION DE TAL COMPRIMIDO
ES198888400340T 1987-02-18 1988-02-16 Comprimido de dihidroergotamina (d.h.e.) del tipo con matriz hidrofila y su procedimiento de fabricacion. Expired - Lifetime ES2037254T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8702076A FR2610827B1 (fr) 1987-02-18 1987-02-18 Comprime de dihydroergotamine (d.h.e.) du type a matrice hydrophile et son procede de fabrication

Publications (1)

Publication Number Publication Date
ES2037254T3 true ES2037254T3 (es) 1993-06-16

Family

ID=9348044

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888400340T Expired - Lifetime ES2037254T3 (es) 1987-02-18 1988-02-16 Comprimido de dihidroergotamina (d.h.e.) del tipo con matriz hidrofila y su procedimiento de fabricacion.

Country Status (7)

Country Link
EP (1) EP0280613B1 (es)
JP (1) JPS63203617A (es)
AT (1) ATE74000T1 (es)
CA (1) CA1340660C (es)
DE (1) DE3869443D1 (es)
ES (1) ES2037254T3 (es)
FR (1) FR2610827B1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2653337B1 (fr) * 1989-10-23 1992-02-07 Dow Corning Sa Element a liberation prolongee et procede pour le fabriquer.
US6210710B1 (en) * 1997-04-28 2001-04-03 Hercules Incorporated Sustained release polymer blend for pharmaceutical applications
EP1169024B1 (en) * 1999-03-31 2005-12-21 Janssen Pharmaceutica N.V. Pregelatinized starch in a controlled release formulation
RU2162324C1 (ru) * 1999-11-23 2001-01-27 Аметов Александр Сергеевич Способ фармакологического лечения психогенной эректильной дисфункции
US7771746B2 (en) 1999-12-03 2010-08-10 Polichem Sa Methods for making sustained-release pharmaceutical compositions of ergot alkaloids having improved bioavailability and compositions thereof
EP1512403A1 (en) * 1999-12-03 2005-03-09 Polichem S.A. Methods for making sustained-release pharmaceutical compositions of ergot alkaloids having improved bioavailability and compositions thereof
TWI338583B (en) 2004-05-20 2011-03-11 Otsuka Pharma Co Ltd Solid pharmaceutical formulation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2546577B2 (de) * 1975-10-17 1981-04-02 Sandoz-Patent-GmbH, 7850 Lörrach Feste Stoffe aus Polyvinylpyrrolidon und Ergotalkaloiden
US4259314A (en) * 1979-12-10 1981-03-31 Hans Lowey Method and composition for the preparation of controlled long-acting pharmaceuticals
US4652442A (en) * 1983-07-05 1987-03-24 Arcana Chem. Pharm. Fabrik Gesellschaft M.B.H. Process of producing a sustained release preparation containing indomethacin or niomethacin
HU195729B (en) * 1985-02-05 1988-07-28 Sandoz Ag Process for producing pharmaceutical compositions containing 9,10-dihydro-ergot-alkaloides
US4608248A (en) * 1985-11-08 1986-08-26 Warner-Lambert Company Process for time-controlled release of active ingredients

Also Published As

Publication number Publication date
EP0280613A1 (fr) 1988-08-31
EP0280613B1 (fr) 1992-03-25
DE3869443D1 (de) 1992-04-30
FR2610827B1 (fr) 1991-09-13
CA1340660C (fr) 1999-07-20
FR2610827A1 (fr) 1988-08-19
ATE74000T1 (de) 1992-04-15
JPS63203617A (ja) 1988-08-23

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