ES2037738T3 - Procedimiento para la obtencion de aminopirazinonas y aminotriazinonas. - Google Patents

Procedimiento para la obtencion de aminopirazinonas y aminotriazinonas.

Info

Publication number
ES2037738T3
ES2037738T3 ES198787810545T ES87810545T ES2037738T3 ES 2037738 T3 ES2037738 T3 ES 2037738T3 ES 198787810545 T ES198787810545 T ES 198787810545T ES 87810545 T ES87810545 T ES 87810545T ES 2037738 T3 ES2037738 T3 ES 2037738T3
Authority
ES
Spain
Prior art keywords
alkyl
hydrogen
alkoxy
halogenoalkyl
alkenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787810545T
Other languages
English (en)
Inventor
Beat Dr. Bohner
Willy Meyer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Application granted granted Critical
Publication of ES2037738T3 publication Critical patent/ES2037738T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D521/00—Heterocyclic compounds containing unspecified hetero rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
    • A01N47/36—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the group >N—CO—N< directly attached to at least one heterocyclic ring; Thio analogues thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/20—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075—Two hetero atoms, in positions 3 and 5

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Agronomy & Crop Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Detergent Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE DESCRIBEN AMINOPIRAZINONAS Y AMINOTRIAZINONAS, DE FORMULA (I), Y LAS SALES DE ESTOS COMPUESTOS CON AMINAS, HIDROXIDOS ALCALINOS O ALCLINOTERREOS O CON BASES DE AMONIO CUATERNARIO QUE TIENEN BUENAS PROPIEDADES COMO HERBICIDAS PRE Y POSTEMERGENTES SELECTIVOS Y REGULADORES DEL CRECIMIENTO. EN LA FORMULA (I), LOS SIMBOLOS E, R1, R2, R3 Y Q TIENEN LOS SIGNIFICADOS QUE SE EXPLICAN EN LA INVENCION.
ES198787810545T 1986-09-26 1987-09-21 Procedimiento para la obtencion de aminopirazinonas y aminotriazinonas. Expired - Lifetime ES2037738T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH387186 1986-09-26

Publications (1)

Publication Number Publication Date
ES2037738T3 true ES2037738T3 (es) 1993-07-01

Family

ID=4265276

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787810545T Expired - Lifetime ES2037738T3 (es) 1986-09-26 1987-09-21 Procedimiento para la obtencion de aminopirazinonas y aminotriazinonas.

Country Status (11)

Country Link
US (4) US4795486A (es)
EP (1) EP0262096B1 (es)
JP (1) JPS6391378A (es)
AT (1) ATE71096T1 (es)
AU (1) AU593945B2 (es)
CA (1) CA1292738C (es)
DE (1) DE3775686D1 (es)
ES (1) ES2037738T3 (es)
GR (1) GR3003528T3 (es)
IL (1) IL83996A (es)
ZA (1) ZA877223B (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3775686D1 (de) * 1986-09-26 1992-02-13 Ciba Geigy Ag Aminopyrazinone und aminotriazinone.
MY136106A (en) * 1990-09-06 2008-08-29 Novartis Ag Synergistic composition comprising a sulfonylurea anda thiadiazolo (3,4-a)pyridazine and method of selective weed control.
JP3140790B2 (ja) * 1996-04-23 2001-03-05 メルク エンド カンパニー インコーポレーテッド ピラジノン系トロンビン阻害薬
US5872138A (en) * 1996-09-13 1999-02-16 Merck & Co., Inc. Thrombin inhibitors
US5869487A (en) * 1996-10-24 1999-02-09 Merck & Co., Inc. Pyrido 3,4-B!pyrazines for use as thrombin inhibitors
US5866573A (en) * 1997-04-21 1999-02-02 Merck & Co., Inc. Pyrazinone thrombin inhibitors
US6011038A (en) * 1997-09-05 2000-01-04 Merck & Co., Inc. Pyrazinone thrombin inhibitors
US6087373A (en) * 1997-09-23 2000-07-11 Merck & Co., Inc. Thrombin inhibitors
US6133297A (en) * 1997-09-30 2000-10-17 Merck & Co., Inc. Thrombin inhibitors
US6147078A (en) * 1998-05-19 2000-11-14 Merck & Co., Inc. Pyrazinone thrombin inhibitors
EP1117660A4 (en) * 1998-09-28 2002-01-09 Merck & Co Inc Thrombin Inhibitors
CA2348734A1 (en) 1998-10-30 2000-05-11 Merck & Co., Inc. Thrombin inhibitors
WO2000026210A1 (en) 1998-10-30 2000-05-11 Merck & Co., Inc. Thrombin inhibitors
US6239132B1 (en) 1999-04-23 2001-05-29 Merck & Co., Inc. Thrombin inhibitors
US6908919B2 (en) * 1999-05-19 2005-06-21 Pharmacia Corporation Substituted polycyclic aryl and heteroaryl pyrazinones useful for selective inhibition of the coagulation cascade
US6664255B1 (en) * 1999-05-19 2003-12-16 Pharmacia Corporation Substituted polycyclic aryl and heteroaryl pyrazinones useful for selective inhibition of the coagulation cascade
UA58636C2 (uk) 1999-06-04 2003-08-15 Мерк Енд Ко., Інк. Піразинонові інгібітори тромбіну, фармацевтична композиція, спосіб інгібування утворення тромбів у крові, спосіб лікування станів, пов'язаних із тромбоутворенням
EP1189618A4 (en) 1999-06-04 2002-06-19 Merck & Co Inc thrombin
JP2003514905A (ja) 1999-11-23 2003-04-22 メルク エンド カムパニー インコーポレーテッド ピラジノン系トロンビン阻害薬
CA2403558A1 (en) 2000-03-23 2001-09-27 Merck & Co., Inc. Thrombin inhibitors
US7119094B1 (en) 2000-11-20 2006-10-10 Warner-Lambert Company Substituted polycyclic aryl and heteroarpyl pyrazinones useful for selective inhibition of the coagulation cascade
SI3259253T1 (sl) 2015-02-16 2020-07-31 The University Of Queensland Sulfonilsečnine in sorodne spojine ter njihova uporaba
JP7072586B2 (ja) 2017-05-24 2022-05-20 ザ ユニバーシティ オブ クィーンズランド 新規な化合物及び使用
EP3649112A1 (en) 2017-07-07 2020-05-13 Inflazome Limited Sulfonylureas and sulfonylthioureas as nlrp3 inhibitors
NZ760129A (en) 2017-07-07 2025-12-19 Inflazome Ltd Novel sulfonamide carboxamide compounds
MA49903A (fr) 2017-08-15 2020-06-24 Inflazome Ltd Sulfonylureés et sulfonylthioureés en tant qu'inhibiteurs de nlrp3
UY37848A (es) 2017-08-15 2019-03-29 Inflazome Ltd Sulfonilureas y sulfoniltioureas útiles como inhibidores de nlrp3
EP3668843A1 (en) 2017-08-15 2020-06-24 Inflazome Limited Sulfonylureas and sulfonylthioureas as nlrp3 inhibitors
CN111315733A (zh) 2017-11-09 2020-06-19 英夫拉索姆有限公司 新颖磺酰胺甲酰胺化合物
WO2019092171A1 (en) 2017-11-09 2019-05-16 Inflazome Limited Novel sulfonamide carboxamide compounds
US11905252B2 (en) 2018-03-02 2024-02-20 Inflazome Limited Compounds

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1330438C (en) * 1980-07-17 1994-06-28 Willy Meyer N-phenylsulfonyl-n'-pyrimidinyl-and-triazinylureas
US4443245A (en) * 1981-07-13 1984-04-17 Ciba-Geigy Corporation N-Phenylsulfonyl-N'-triazinylureas
US4612037A (en) * 1982-05-28 1986-09-16 Ciba-Geigy Corporation Novel sulfonylureas and sulfonylthioureas, and method of use thereof as herbicides and/or growth regulators
DE3479213D1 (en) * 1983-05-16 1989-09-07 Ciba Geigy Ag Herbicidally active and plant growth regulating pyrimidine derivatives, their preparation and use
AU576868B2 (en) * 1984-06-11 1988-09-08 E.I. Du Pont De Nemours And Company Thiophene and pyridine sulfonamides
US4659369A (en) * 1984-08-27 1987-04-21 E. I. Du Pont De Nemours And Company Herbicidal acetals and ketals
US4690705A (en) * 1984-11-30 1987-09-01 E. I. Du Pont De Nemours And Company Herbicidal sulfonamides
DE3775686D1 (de) * 1986-09-26 1992-02-13 Ciba Geigy Ag Aminopyrazinone und aminotriazinone.
US4802908A (en) * 1987-01-22 1989-02-07 E. I. Du Pont De Nemours And Company Herbicidal 2-(1H)-pyrazinones

Also Published As

Publication number Publication date
EP0262096B1 (de) 1992-01-02
IL83996A (en) 1992-03-29
US4871853A (en) 1989-10-03
US4795486A (en) 1989-01-03
ATE71096T1 (de) 1992-01-15
EP0262096A1 (de) 1988-03-30
GR3003528T3 (es) 1993-03-16
ZA877223B (en) 1988-03-28
AU7897787A (en) 1988-03-31
AU593945B2 (en) 1990-02-22
DE3775686D1 (de) 1992-02-13
IL83996A0 (en) 1988-02-29
US4920223A (en) 1990-04-24
CA1292738C (en) 1991-12-03
US4940482A (en) 1990-07-10
JPS6391378A (ja) 1988-04-22

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