ES2038169T3 - Procedimiento para la obtencion de derivados de dihidropirano. - Google Patents

Procedimiento para la obtencion de derivados de dihidropirano.

Info

Publication number
ES2038169T3
ES2038169T3 ES198787301909T ES87301909T ES2038169T3 ES 2038169 T3 ES2038169 T3 ES 2038169T3 ES 198787301909 T ES198787301909 T ES 198787301909T ES 87301909 T ES87301909 T ES 87301909T ES 2038169 T3 ES2038169 T3 ES 2038169T3
Authority
ES
Spain
Prior art keywords
alkyl
archyl
cycloalkyl
arylalkyl
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787301909T
Other languages
English (en)
Inventor
Ralph William Turner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Application granted granted Critical
Publication of ES2038169T3 publication Critical patent/ES2038169T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

LA INVENCION SE REFIERE A LOS COMPUESTOS DE FORMULA (I), EN DONDE R1 ES ALQUILO, CICLOALQUILO CUYOS GRUPOS ALQUILO Y CICLOALQUILO PUEDEN SER SUSTITUIDOS, ARILO, ARILALQUILO O SILILO (PORTANDO SUSTITUYENTES ALQUILO, ARILO O ARILALQUILO); R2 ES HIDROGENO O ALQUILO; R3 ES HIDROGENO, ALQUILO, CICLOALQUILO (CUYOS GRUPOS ALQUILO Y CICLOALQUILO PUEDEN ESTAR SUSTITUIDOS) ALQUENILO, ARILO, ARILALQUILO, AMINO, MONO- O DIALQUILAMINO O UN GRUPO DE FORMULA -OR5 EN EL QUE R5 ES SUSTITUIDO OPCIONALMENTE POR ALQUILO, ARILO O ARILALQUILO; R4 ES UN ALQUILO OPCIONALMENTE SUSTITUIDO POR UNO O MAS GRUPOS ALCOXI O ATOMOS DE HALOGENOS; Y ES ALCOXI O CICLOALCOXI: SUSTITUIDO OPCIONALMENTE, ARILALCOXI O UN GRUPO DE FORMULA -NR6R7 EN EL QUE R6 ES HIDROGENO O ALQUILO Y R7 ES ALQUILO, CICLOALQUILO (CUYOS GRUPOS ALQUILO Y CICLOALQUILO PUEDEN ESTAR SUSTITUIDOS), ARILO O ARILALQUILO O R7 ES UN GRUPO DE FORMULA COOR8 EN DONDE R8 ES ALQUILO O ARILALQUILO. LOS COMPUESTOS SE UTILIZAN COMO PRODUCTOS INTERMEDIOS EN LA SINTESIS DE ANTIBIOTICOS BETA-LACTAMICOS, PARTICULARMENTE CARBAPENEMS, Y TAMBIEN SE DESCRIBE UN PROCESO PARA LA MANUFACTURA DE DICHOS COMPUESTOS.
ES198787301909T 1986-03-05 1987-03-05 Procedimiento para la obtencion de derivados de dihidropirano. Expired - Lifetime ES2038169T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868605413A GB8605413D0 (en) 1986-03-05 1986-03-05 Chemical compounds

Publications (1)

Publication Number Publication Date
ES2038169T3 true ES2038169T3 (es) 1993-07-16

Family

ID=10594069

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787301909T Expired - Lifetime ES2038169T3 (es) 1986-03-05 1987-03-05 Procedimiento para la obtencion de derivados de dihidropirano.

Country Status (7)

Country Link
US (1) US4962209A (es)
EP (1) EP0236138B1 (es)
JP (1) JPS62265280A (es)
AT (1) ATE65998T1 (es)
DE (1) DE3771894D1 (es)
ES (1) ES2038169T3 (es)
GB (1) GB8605413D0 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021193786A1 (ja) * 2020-03-27 2021-09-30 北興化学工業株式会社 ６－（フルオロアルキル）－３，４－ジヒドロ－２ｈ－ピラン－５－カルボン酸エステル誘導体、および当該誘導体の製造方法、並びに２－（フルオロアルキル）ニコチン酸エステル誘導体の製造方法、および２－（フルオロアルキル）ニコチン酸誘導体の製造方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4282148A (en) * 1980-01-14 1981-08-04 Merck & Co., Inc. Synthesis of thienamycin via esters of (3SR, 4RS)-3-[(SR)-1-hydroxyethyl]-β,2-dioxo-4-azetidinebutanoic acid
US4344885A (en) * 1980-01-14 1982-08-17 Merck & Co., Inc. Intermediate for the preparation of thienamycin
US4349687A (en) * 1980-01-14 1982-09-14 Merck & Co., Inc. Intermediate for synthesis of thienamycin via (3SR, 4RS)-3-[1 (SR)-hydroxyethyl]-2-oxo-4-azetidineacetic acid
US4287123A (en) * 1980-01-14 1981-09-01 Merck & Co., Inc. Synthesis of thienamycin via (3SR, 4RS)-3-((RS)-1-acyloxyethyl)-2-oxo-4-azetidineacetate
US4269772A (en) * 1980-01-14 1981-05-26 Merck & Co., Inc. Synthesis of thienamycin via trans-3-carboxymethylene-4-carboxy-5-methyl-Δ2 -isoxazoline
US4491659A (en) * 1981-03-30 1985-01-01 Merck & Co., Inc. 2,6-Didioxy-3-amine,4-carboxy methylglycoside and related compounds
US4360684A (en) * 1981-04-08 1982-11-23 Merck & Co., Inc. Process for the preparation of (2S)-tetrahydro-2α-methyl-6-oxo-4βα-carboxylic acid
HU190404B (en) * 1982-07-30 1986-09-29 Richter Gedeon Vegyeszeti Gyar Rt,Hu Process for preparing amino-lactone-carboxylic acid

Also Published As

Publication number Publication date
DE3771894D1 (de) 1991-09-12
JPS62265280A (ja) 1987-11-18
US4962209A (en) 1990-10-09
EP0236138B1 (en) 1991-08-07
EP0236138A1 (en) 1987-09-09
GB8605413D0 (en) 1986-04-09
ATE65998T1 (de) 1991-08-15

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