ES2038294T3 - Un procedimiento para preparar una composicion farmaceutica que contiene ibuprofeno. - Google Patents

Un procedimiento para preparar una composicion farmaceutica que contiene ibuprofeno.

Info

Publication number
ES2038294T3
ES2038294T3 ES88306140T ES88306140T ES2038294T3 ES 2038294 T3 ES2038294 T3 ES 2038294T3 ES 88306140 T ES88306140 T ES 88306140T ES 88306140 T ES88306140 T ES 88306140T ES 2038294 T3 ES2038294 T3 ES 2038294T3
Authority
ES
Spain
Prior art keywords
composition
pharmaceutical composition
ibuprophen
preparing
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88306140T
Other languages
English (en)
Inventor
Alan Smith
John Francis Lampard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boots Co PLC
Original Assignee
Boots Co PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co PLC filed Critical Boots Co PLC
Application granted granted Critical
Publication of ES2038294T3 publication Critical patent/ES2038294T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/485—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

SE CONSIGUE UN ALTO CONTENIDO EN ACIDO 2-(4-ISOBUTILFENL) PROPIONICO EN UNA COMPOSICION FARMACEUTICA SOLIDIFICANDO ACIDO 2-(4-ISOBUTILFENIL) PROPIONICO FUNDIDO PARA OBTENER UNA COMPOSICION DE DOSIS UNITARIA. LA COMPOSICION SE PUEDE PREPARAR POR CALENTAMIENTO DEL ACIDO 2-(4-ISOBUTILFENIL) PROPIONICO HASTA FUSION, MEZCLADO OPCIONAL CON EXCIPIENTES FARMACEUTICOS ACEPTABLES, FORMACION DE UNA PRESENTACION EN DOSIS UNITARIA, Y PERMITIR QUE SOLIDIFIQUE LA COMPOSICION. PREFERIBLEMENTE LA COMPOSICION CONTIENE MAS QUE 80 % DE IBUPROFEN O S(+)-IBUPROFEN Y SE CARGA EN UNA CAPSULA DE GELATINA DURA.
ES88306140T 1987-07-17 1988-07-06 Un procedimiento para preparar una composicion farmaceutica que contiene ibuprofeno. Expired - Lifetime ES2038294T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878716975A GB8716975D0 (en) 1987-07-17 1987-07-17 Therapeutic agents

Publications (1)

Publication Number Publication Date
ES2038294T3 true ES2038294T3 (es) 1993-07-16

Family

ID=10620872

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88306140T Expired - Lifetime ES2038294T3 (es) 1987-07-17 1988-07-06 Un procedimiento para preparar una composicion farmaceutica que contiene ibuprofeno.

Country Status (4)

Country Link
EP (1) EP0299668B1 (es)
DE (1) DE3865908D1 (es)
ES (1) ES2038294T3 (es)
GB (1) GB8716975D0 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4980375A (en) * 1987-07-10 1990-12-25 Sterling Drug Inc. Onset-hastened/enhanced antipyretic response
RU2079301C1 (ru) * 1989-01-31 1997-05-20 Др.Цозер Б.Салама Способ регулируемого выделения активного вещества из состава
AU643210B2 (en) * 1989-05-16 1993-11-11 Medice Chem.-Pharm. Fabrik Putter Gmbh & Co. Kg Process for preparing optically active 2-aryl-alkanoic acids, in particular 2-ayrl-propionic acids
DE3922441A1 (de) * 1989-07-07 1991-01-17 Pharmatrans Sanaq Ag Ibuprofen- und s-(+)-ibuprofen-zubereitungen und verfahren zu ihrer herstellung
DK138592D0 (da) * 1992-11-17 1992-11-17 Nycomed Dak As Tabletter
GB2281697A (en) * 1993-09-14 1995-03-15 Euro Celtique Sa Laxative compositions in capsules
GB9325445D0 (en) 1993-12-13 1994-02-16 Cortecs Ltd Pharmaceutical formulations
AT401871B (de) * 1994-01-28 1996-12-27 Gebro Broschek Gmbh Verfahren zur herstellung von s(+)-ibuprofen- partikeln mit verbesserten fliesseigenschaften und deren verwendung zur arzneimittelherstellung
GB2293099A (en) * 1994-09-15 1996-03-20 Mailway Packaging Group Ltd Drug formulation
EP0818990A1 (en) * 1995-04-03 1998-01-21 Abbott Laboratories Homogeneous mixtures of low temperature-melting drugs and additives for controlled release
IT1318654B1 (it) * 2000-07-28 2003-08-27 Prodotti Antibiotici Spa Composizioni farmaceutiche comprendenti agenti antiinfiammatori e lorousi.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1617362A1 (de) * 1967-11-17 1971-03-25 Beiersdorf Ag Verfahren zur Herstellung von Arzneimitteln mit verzoegerter Wirkstoffabgabe in Form von Kapseln
JPS56120616A (en) * 1980-02-27 1981-09-22 Kaken Pharmaceut Co Ltd Ibuprofen-containing granule, its preparation, and internal medicine comprising it
JPS57145807A (en) * 1981-03-06 1982-09-09 Kowa Yakuhin Kogyo Kk Preparation of ibuprofen pharmaceutical
DE3437599C2 (de) * 1984-10-13 1987-04-16 Dolorgiet GmbH & Co KG, 5205 St Augustin Ibuprofen enthaltende Weichgelatinekapseln

Also Published As

Publication number Publication date
EP0299668A1 (en) 1989-01-18
GB8716975D0 (en) 1987-08-26
EP0299668B1 (en) 1991-10-30
DE3865908D1 (de) 1991-12-05

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