ES2038578T1 - Utilizacion de inmunoglobulinas g humanas, o de fragmentos fc de estas, como medicamento preparatorio para la administracion al hombre de anticuerpos monoclonales. - Google Patents

Utilizacion de inmunoglobulinas g humanas, o de fragmentos fc de estas, como medicamento preparatorio para la administracion al hombre de anticuerpos monoclonales.

Info

Publication number
ES2038578T1
ES2038578T1 ES198989403245T ES89403245T ES2038578T1 ES 2038578 T1 ES2038578 T1 ES 2038578T1 ES 198989403245 T ES198989403245 T ES 198989403245T ES 89403245 T ES89403245 T ES 89403245T ES 2038578 T1 ES2038578 T1 ES 2038578T1
Authority
ES
Spain
Prior art keywords
monoclonal antibodies
fragments
human
immunoglobulins
men
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
ES198989403245T
Other languages
English (en)
Inventor
Edgardo D. Carosella
Jean-Francois Bach
Jacques Bernard Armand
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Pasteur SA
Original Assignee
Pasteur Merieux Serum et Vaccines SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pasteur Merieux Serum et Vaccines SA filed Critical Pasteur Merieux Serum et Vaccines SA
Publication of ES2038578T1 publication Critical patent/ES2038578T1/es
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Transplantation (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

USO DE FRAGMENTOS FC DE IGG HUMANOS EN LA PRODUCCION DE UN MEDICAMENTO PREPARATORIO PARA ADMINISTRAR AL HOMBRE, CON UN FIN TERAPEUTICO O DE DIAGNOSTICO, DE ANTICUERPOS MONOCLONALES. EL TRATAMIENTO PREPARATORIO CON LOS FRAGMENTOS FC PERMITE DISMINUIR LA FIJACION NO ESPECIFCIA Y LOS EFECTOS SECUNDARIOS DE LOS ANTICUERPOS MONOCLONALES. LAS DOSIS DE ANTICUERPOS MONOCLONALES PUEDEN SER REDUCIDAD.
ES198989403245T 1988-11-23 1989-11-23 Utilizacion de inmunoglobulinas g humanas, o de fragmentos fc de estas, como medicamento preparatorio para la administracion al hombre de anticuerpos monoclonales. Pending ES2038578T1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8815269A FR2639231A1 (fr) 1988-11-23 1988-11-23 Utilisation de fragments fc d'immunoglobulines g humaines, de peptides analogues du fragment fc, ou d'immunoglobulines g humaines dans l'obtention d'un medicament preparatoire a l'administration chez l'homme, dans un but therapeutique ou de diagnostic, d'anticorps monoclonaux

Publications (1)

Publication Number Publication Date
ES2038578T1 true ES2038578T1 (es) 1993-08-01

Family

ID=9372154

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198989403245T Pending ES2038578T1 (es) 1988-11-23 1989-11-23 Utilizacion de inmunoglobulinas g humanas, o de fragmentos fc de estas, como medicamento preparatorio para la administracion al hombre de anticuerpos monoclonales.

Country Status (6)

Country Link
EP (1) EP0376770A1 (es)
JP (1) JPH02231431A (es)
DE (1) DE376770T1 (es)
ES (1) ES2038578T1 (es)
FR (1) FR2639231A1 (es)
GR (1) GR910300049T1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9009106D0 (en) * 1990-04-23 1990-06-20 3I Res Expl Ltd Processes and intermediates for synthetic antibody derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2556219B1 (fr) * 1983-12-07 1987-06-26 Merieux Inst Nouveau medicament immunomodulateur, a base de fragments fc d'igg humaines
JPS62153300A (ja) * 1985-12-26 1987-07-08 Teijin Ltd ヒト免疫グロブリンＧＦｃ領域蛋白質およびその製造方法
JP2515357B2 (ja) * 1986-01-16 1996-07-10 ザ・ジェネラル・ホスピタル・コ−ポレ−ション 炎症の診断方法および治療方法
EP0288520B1 (en) * 1986-10-09 1995-05-24 Neorx Corporation Use and composition for improved targeting of antibody, antibody fragments, and conjugates thereof

Also Published As

Publication number Publication date
FR2639231A1 (fr) 1990-05-25
GR910300049T1 (en) 1991-11-15
DE376770T1 (de) 1991-07-25
JPH02231431A (ja) 1990-09-13
EP0376770A1 (fr) 1990-07-04

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