ES2038703T3 - Procedimiento para la determinacion de inhibidor de la proteina c. - Google Patents

Procedimiento para la determinacion de inhibidor de la proteina c.

Info

Publication number
ES2038703T3
ES2038703T3 ES198888102144T ES88102144T ES2038703T3 ES 2038703 T3 ES2038703 T3 ES 2038703T3 ES 198888102144 T ES198888102144 T ES 198888102144T ES 88102144 T ES88102144 T ES 88102144T ES 2038703 T3 ES2038703 T3 ES 2038703T3
Authority
ES
Spain
Prior art keywords
inhibitor
protein
determination
procedure
liquid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888102144T
Other languages
English (en)
Inventor
Thomas Dr. Stief
Norbert Prof. Dr. Heimburger
Klaus-Peter Dr. Radtke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics GmbH Germany
Original Assignee
Behringwerke AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke AG filed Critical Behringwerke AG
Application granted granted Critical
Publication of ES2038703T3 publication Critical patent/ES2038703T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745—Assays involving non-enzymic blood coagulation factors
    • G01N2333/75—Fibrin; Fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433—Serine endopeptidases (3.4.21)
    • G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
    • G01N2333/96461—Protein C (3.4.21.69)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/972—Plasminogen activators
    • G01N2333/9723—Urokinase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/38—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence, e.g. gluco- or galactomannans, Konjac gum, Locust bean gum or Guar gum
    • G01N2400/40—Glycosaminoglycans, i.e. GAG or mucopolysaccharides, e.g. chondroitin sulfate, dermatan sulfate, hyaluronic acid, heparin, heparan sulfate, and related sulfated polysaccharides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)

Abstract

SE DESCRIBE UN PROCEDIMIENTO Y UN MEDIO PARA DETERMINACIONES FUNCIONALES DE PROTEINAS INHIBIDORES DE C EN LIQUIDO CONSTISTE EN : ADICIONAR EL LIQUIDO CON UNA CANTIDAD DE ACTUACIONES DE PLASMINOGENO, FIBRINOGENO Y UN HIDRATO DE CARBONO SULFATADO; INCUBAR EL LIQUIDO ADICIONADO; DETERMINAR LA ACTIVIDAD DEL RECTO DE ACTUADORES DE PLASMINOGNO Y CALCULAR LA CANTIDAD DE PROTEINAS EN INHIBIDORES DE C.
ES198888102144T 1987-02-23 1988-02-13 Procedimiento para la determinacion de inhibidor de la proteina c. Expired - Lifetime ES2038703T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873705744 DE3705744A1 (de) 1987-02-23 1987-02-23 Verfahren zur funktionellen bestimmung von protein c-inhibitor

Publications (1)

Publication Number Publication Date
ES2038703T3 true ES2038703T3 (es) 1993-08-01

Family

ID=6321570

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888102144T Expired - Lifetime ES2038703T3 (es) 1987-02-23 1988-02-13 Procedimiento para la determinacion de inhibidor de la proteina c.

Country Status (8)

Country Link
US (1) US5512449A (es)
EP (1) EP0281791B1 (es)
JP (1) JP2674063B2 (es)
AT (1) ATE85365T1 (es)
AU (1) AU607740B2 (es)
CA (1) CA1323549C (es)
DE (2) DE3705744A1 (es)
ES (1) ES2038703T3 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014205426A1 (en) * 2013-06-21 2014-12-24 Imigene, Inc. Blood analysis

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3931399A (en) * 1970-12-22 1976-01-06 Behringwerke Aktiengesellschaft Process for isolating a fibrin-stabilizing factor
US4791068A (en) * 1984-06-22 1988-12-13 Scripps Clinic And Research Foundation Diagnostic assay for inhibitor of tissue-type and urokinase-type plasminogen activators
DE3502878A1 (de) * 1985-01-29 1986-07-31 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur bestimmung des fibrinolytischen zustands von plasma
DE3512909A1 (de) * 1985-04-11 1986-10-23 Behringwerke Ag, 3550 Marburg Verfahren zur bestimmung von plasminogenaktivatoren (pa)
DE3722082A1 (de) * 1987-07-03 1989-01-12 Behringwerke Ag Verfahren zur bestimmung der aktivitaet von serinproteasen oder serinproteaseinhibitoren
US5358932A (en) * 1989-12-29 1994-10-25 Zymogenetics, Inc. Hybrid protein C

Also Published As

Publication number Publication date
JP2674063B2 (ja) 1997-11-05
ATE85365T1 (de) 1993-02-15
EP0281791B1 (de) 1993-02-03
AU607740B2 (en) 1991-03-14
EP0281791A1 (de) 1988-09-14
DE3877988D1 (de) 1993-03-18
JPS63237799A (ja) 1988-10-04
DE3705744A1 (de) 1988-09-01
AU1200388A (en) 1988-08-04
US5512449A (en) 1996-04-30
CA1323549C (en) 1993-10-26

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