ES2038780T3 - Procedimiento para la preparacion de nuevos compuestos triciclicos. - Google Patents
Procedimiento para la preparacion de nuevos compuestos triciclicos.Info
- Publication number
- ES2038780T3 ES2038780T3 ES198888403289T ES88403289T ES2038780T3 ES 2038780 T3 ES2038780 T3 ES 2038780T3 ES 198888403289 T ES198888403289 T ES 198888403289T ES 88403289 T ES88403289 T ES 88403289T ES 2038780 T3 ES2038780 T3 ES 2038780T3
- Authority
- ES
- Spain
- Prior art keywords
- image
- procedure
- preparation
- group
- agonists
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 108010009685 Cholinergic Receptors Proteins 0.000 abstract 2
- 102000034337 acetylcholine receptors Human genes 0.000 abstract 2
- 239000000556 agonist Substances 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
Abstract
LA INVENCION SE REFIERE A NUEVOS DERIVADOS TRICICLICOS AGONISTAS DE RECEPTORES COLINERGICOS. SE REFIERE TAMBIEN A UN PROCEDIMIENTO PARA SU PREPARACION Y COMPOSICIONES FARMACEUTICAS QUE LAS CONTIENEN. ESTOS DERIVADOS RESPONDEN A LA FORMULA(I), EN LA QUE X ES O, S - OCH2 - O SCH2; R1 ES H O HALOGENO; R2 ES H O HALOGENO. ALK ES UN GRUPO ALQUILENO, R3 Y R4 IGUALES O DIFERENTES SON H, UN GRUPO ALQUILO INFERIOR O R3 Y R4 FORMAN CON EL ATOMO DE N AL QUE ESTAN UNIDOS UN GRUPO AMINO CICLICO DE 5 O 6 CADENAS CON EVENTUALMENTE UN SEGUNDO HETEROATOMO. APLICACION AGONISTAS DE RECEPTORES COLINERGICOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8718187A FR2625201B1 (fr) | 1987-12-24 | 1987-12-24 | Nouveaux derives tricycliques agonistes des recepteurs cholinergiques et medicaments en contenant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2038780T3 true ES2038780T3 (es) | 1993-08-01 |
Family
ID=9358327
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES198888403289T Expired - Lifetime ES2038780T3 (es) | 1987-12-24 | 1988-12-22 | Procedimiento para la preparacion de nuevos compuestos triciclicos. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4983603A (es) |
| EP (1) | EP0323325B1 (es) |
| JP (1) | JPH01203387A (es) |
| AT (1) | ATE68496T1 (es) |
| CA (1) | CA1314885C (es) |
| DE (1) | DE3865656D1 (es) |
| ES (1) | ES2038780T3 (es) |
| FR (1) | FR2625201B1 (es) |
| GR (1) | GR3003161T3 (es) |
| PT (1) | PT89290B (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USD368593S (en) | 1994-11-04 | 1996-04-09 | Cosco, Inc. | High chair |
| US5509719A (en) * | 1994-11-04 | 1996-04-23 | Cosco, Inc. | Multi-position chair |
| EP1928437A2 (en) * | 2005-08-26 | 2008-06-11 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
| EP2490692B1 (en) * | 2009-10-21 | 2016-11-16 | Merck Sharp & Dohme Corp. | Quinolinone-pyrazolone m1 receptor positive allosteric modulators |
| KR102127406B1 (ko) | 2012-09-20 | 2020-06-29 | 유디씨 아일랜드 리미티드 | 전자 응용을 위한 아자디벤조푸란 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3464988A (en) * | 1968-01-11 | 1969-09-02 | Bristol Myers Co | 3-hydrazinobenzo(h)cinnolines and 3 - hydrazinobenzocyclohepta-(5,6-c)pyridazines |
| GB1345880A (en) * | 1971-06-18 | 1974-02-06 | Cepbepe | Pyridazine derivatives |
| US4701453A (en) * | 1984-02-02 | 1987-10-20 | Warner-Lambert Company | Substituted indeno-pyridazinones |
| FR2601011B1 (fr) * | 1986-07-03 | 1988-10-28 | Sanofi Sa | Nouveaux derives tricycliques agonistes des recepteurs cholinergiques et medicaments en contenant |
| FR2619818B1 (fr) * | 1987-09-01 | 1990-01-12 | Sanofi Sa | Imidazo (1,2-b) pyridazines, procede pour leur preparation et compositions pharmaceutiques les contenant |
-
1987
- 1987-12-24 FR FR8718187A patent/FR2625201B1/fr not_active Expired - Fee Related
-
1988
- 1988-12-21 PT PT89290A patent/PT89290B/pt not_active IP Right Cessation
- 1988-12-22 CA CA000586850A patent/CA1314885C/en not_active Expired - Fee Related
- 1988-12-22 DE DE8888403289T patent/DE3865656D1/de not_active Expired - Fee Related
- 1988-12-22 AT AT88403289T patent/ATE68496T1/de not_active IP Right Cessation
- 1988-12-22 ES ES198888403289T patent/ES2038780T3/es not_active Expired - Lifetime
- 1988-12-22 EP EP88403289A patent/EP0323325B1/fr not_active Expired - Lifetime
- 1988-12-23 US US07/288,861 patent/US4983603A/en not_active Expired - Fee Related
- 1988-12-24 JP JP63327502A patent/JPH01203387A/ja active Pending
-
1991
- 1991-11-21 GR GR91401790T patent/GR3003161T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPH01203387A (ja) | 1989-08-16 |
| ATE68496T1 (de) | 1991-11-15 |
| EP0323325A1 (fr) | 1989-07-05 |
| PT89290B (pt) | 1993-08-31 |
| PT89290A (pt) | 1989-12-29 |
| FR2625201A1 (fr) | 1989-06-30 |
| DE3865656D1 (de) | 1991-11-21 |
| US4983603A (en) | 1991-01-08 |
| GR3003161T3 (en) | 1993-02-17 |
| EP0323325B1 (fr) | 1991-10-16 |
| CA1314885C (en) | 1993-03-23 |
| FR2625201B1 (fr) | 1990-06-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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