ES2039248T3 - Un procedimiento para preparar una forma terapeutica de acetominofen secado por pulverizacion. - Google Patents
Un procedimiento para preparar una forma terapeutica de acetominofen secado por pulverizacion.Info
- Publication number
- ES2039248T3 ES2039248T3 ES87309256T ES87309256T ES2039248T3 ES 2039248 T3 ES2039248 T3 ES 2039248T3 ES 87309256 T ES87309256 T ES 87309256T ES 87309256 T ES87309256 T ES 87309256T ES 2039248 T3 ES2039248 T3 ES 2039248T3
- Authority
- ES
- Spain
- Prior art keywords
- acetominofen
- preparing
- procedure
- spray dried
- therapeutic form
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 abstract 4
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 abstract 2
- 239000001856 Ethyl cellulose Substances 0.000 abstract 2
- 235000019325 ethyl cellulose Nutrition 0.000 abstract 2
- 229920001249 ethyl cellulose Polymers 0.000 abstract 2
- 229960005489 paracetamol Drugs 0.000 abstract 2
- 239000000843 powder Substances 0.000 abstract 2
- 239000007910 chewable tablet Substances 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 238000001694 spray drying Methods 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physiology (AREA)
- Organic Chemistry (AREA)
- Nutrition Science (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Glanulating (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/921,556 US4767789A (en) | 1986-10-21 | 1986-10-21 | Spray dried acetaminophen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2039248T3 true ES2039248T3 (es) | 1995-04-01 |
Family
ID=25445618
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES87309256T Expired - Lifetime ES2039248T3 (es) | 1986-10-21 | 1987-10-20 | Un procedimiento para preparar una forma terapeutica de acetominofen secado por pulverizacion. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4767789A (de) |
| EP (1) | EP0268383B1 (de) |
| JP (1) | JP2550364B2 (de) |
| KR (1) | KR950014442B1 (de) |
| AT (1) | ATE64309T1 (de) |
| AU (1) | AU594202B2 (de) |
| CA (1) | CA1308662C (de) |
| DE (1) | DE3770767D1 (de) |
| ES (1) | ES2039248T3 (de) |
| GR (1) | GR3002127T3 (de) |
| IE (1) | IE61953B1 (de) |
| NZ (1) | NZ222107A (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5270056A (en) * | 1985-10-25 | 1993-12-14 | Aktiebolaget Hassle | Particle having a dyed coke indicator and a pharmaceutical coating for parenteral administration of the pharmaceutical |
| US5612059A (en) * | 1988-08-30 | 1997-03-18 | Pfizer Inc. | Use of asymmetric membranes in delivery devices |
| US4946684A (en) * | 1989-06-20 | 1990-08-07 | American Home Products Corporation | Fast dissolving dosage forms |
| US5037658A (en) * | 1989-09-14 | 1991-08-06 | Hoechst-Roussel Pharmaceuticals, Inc. | Direct dry compressible acetaminophen composition |
| US5130140A (en) * | 1989-09-14 | 1992-07-14 | Hoeschst-Roussel Pharmaceuticals Inc. | Method of making direct dry compressible acetaminophen composition |
| US5198228A (en) * | 1989-09-14 | 1993-03-30 | Hoechst-Roussel Pharmaceuticals Inc. | Direct dry compressible acetaminophen tablet |
| ATE118345T1 (de) * | 1990-08-07 | 1995-03-15 | Pfizer | Verwendung von interfacial polymerisierten membranen in abgabevorrichtungen. |
| US5562919A (en) * | 1993-05-20 | 1996-10-08 | American Meat Protein Corporation | Dried animal plasma as a pharmaceutical excipient for compressed tablet formulation |
| AUPN940796A0 (en) * | 1996-04-23 | 1996-05-16 | F.H. Faulding & Co. Limited | Taste masked pharmaceutical compositions |
| US5795586A (en) * | 1996-08-07 | 1998-08-18 | De Novo, Inc. | Toxin decontaminant food product and method of forming same |
| US6294189B1 (en) | 1996-08-07 | 2001-09-25 | De Novo, Inc. | Method of forming decontaminant food product |
| US6432442B1 (en) | 1998-02-23 | 2002-08-13 | Mcneil-Ppc, Inc. | Chewable product |
| JP2003508420A (ja) | 1999-09-02 | 2003-03-04 | ノストラム・ファーマスーティカルズ・インコーポレイテッド | 経口投与に適した、制御された放出の経口用量 |
| US7972621B2 (en) * | 2004-06-03 | 2011-07-05 | R.P. Scherer Technologies, Llc | Process for formulating fast dispersing dosage forms comprising at least one fish gelatin selected on the basis of molecular weight |
| JP5026675B2 (ja) * | 2005-03-08 | 2012-09-12 | 洋文 竹内 | 錠剤、およびその製造方法 |
| US7811604B1 (en) | 2005-11-14 | 2010-10-12 | Barr Laboratories, Inc. | Non-effervescent, orally disintegrating solid pharmaceutical dosage forms comprising clozapine and methods of making and using the same |
| US9925138B2 (en) | 2015-01-20 | 2018-03-27 | Handa Pharmaceuticals, Llc | Stable solid fingolimod dosage forms |
| IL267689B2 (en) | 2016-12-31 | 2025-05-01 | Bioxcel Therapeutics Inc | Use of sublingual dexmedetomidine for the treatment of agitation |
| BR112020026672A2 (pt) | 2018-06-27 | 2021-03-30 | Bioxcel Therapeutics, Inc. | Formulações de filme contendo dexmedetomidina e métodos para produzi-las |
| BR112022000992A2 (pt) | 2019-07-19 | 2022-06-14 | Arx Llc | Regimes de tratamento de dexmedetomidina não sedantes |
| US11806334B1 (en) | 2023-01-12 | 2023-11-07 | Bioxcel Therapeutics, Inc. | Non-sedating dexmedetomidine treatment regimens |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5420572B2 (de) * | 1973-04-27 | 1979-07-24 | ||
| JPS51118816A (en) * | 1975-04-08 | 1976-10-19 | Meiji Seika Kaisha Ltd | A process for stabilizing non-crystalloidal solid |
| IE45770B1 (en) * | 1976-10-06 | 1982-11-17 | Wyeth John & Brother Ltd | Pharmaceutical dosage forms |
| DE3173600D1 (en) * | 1980-05-20 | 1986-03-13 | Mallinckrodt Inc | Spray dried n-acetyl-p-aminophenol compositions and method for manufacture thereof |
| US4439453A (en) * | 1980-12-22 | 1984-03-27 | Monsanto Company | Directly compressible acetaminophen granulation |
| JPS58172311A (ja) * | 1982-04-02 | 1983-10-11 | Kodama Kk | 持続性製剤及びその製法 |
| US4631284A (en) * | 1984-11-19 | 1986-12-23 | Mallinckrodt, Inc. | Acetaminophen compositions containing low doses of chlorpheniramine maleate, method for preparing same and tablets formed therefrom |
-
1986
- 1986-10-21 US US06/921,556 patent/US4767789A/en not_active Expired - Lifetime
-
1987
- 1987-10-09 NZ NZ222107A patent/NZ222107A/xx unknown
- 1987-10-09 AU AU79508/87A patent/AU594202B2/en not_active Ceased
- 1987-10-09 CA CA000548999A patent/CA1308662C/en not_active Expired - Fee Related
- 1987-10-13 IE IE275287A patent/IE61953B1/en not_active IP Right Cessation
- 1987-10-20 KR KR1019870011622A patent/KR950014442B1/ko not_active Expired - Fee Related
- 1987-10-20 JP JP62266141A patent/JP2550364B2/ja not_active Expired - Lifetime
- 1987-10-20 AT AT87309256T patent/ATE64309T1/de not_active IP Right Cessation
- 1987-10-20 EP EP87309256A patent/EP0268383B1/de not_active Expired - Lifetime
- 1987-10-20 DE DE8787309256T patent/DE3770767D1/de not_active Expired - Fee Related
- 1987-10-20 ES ES87309256T patent/ES2039248T3/es not_active Expired - Lifetime
-
1991
- 1991-06-13 GR GR91400706T patent/GR3002127T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE64309T1 (de) | 1991-06-15 |
| KR950014442B1 (ko) | 1995-11-28 |
| US4767789A (en) | 1988-08-30 |
| DE3770767D1 (de) | 1991-07-18 |
| AU7950887A (en) | 1988-04-28 |
| GR3002127T3 (en) | 1992-12-30 |
| IE61953B1 (en) | 1994-11-30 |
| JPS63112516A (ja) | 1988-05-17 |
| NZ222107A (en) | 1989-07-27 |
| EP0268383A1 (de) | 1988-05-25 |
| EP0268383B1 (de) | 1991-06-12 |
| JP2550364B2 (ja) | 1996-11-06 |
| IE872752L (en) | 1988-04-21 |
| KR880004803A (ko) | 1988-06-27 |
| AU594202B2 (en) | 1990-03-01 |
| CA1308662C (en) | 1992-10-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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