ES2039506T3 - Un procedimiento para la preparacion del compuesto n,n'-dimetil-n-(3,4,5-trimetoxibencil)-n'-(3,3-di-(4-fluorofenil)-propil)-etilendiamina. - Google Patents

Un procedimiento para la preparacion del compuesto n,n'-dimetil-n-(3,4,5-trimetoxibencil)-n'-(3,3-di-(4-fluorofenil)-propil)-etilendiamina.

Info

Publication number
ES2039506T3
ES2039506T3 ES198888108933T ES88108933T ES2039506T3 ES 2039506 T3 ES2039506 T3 ES 2039506T3 ES 198888108933 T ES198888108933 T ES 198888108933T ES 88108933 T ES88108933 T ES 88108933T ES 2039506 T3 ES2039506 T3 ES 2039506T3
Authority
ES
Spain
Prior art keywords
compound
etilendiamina
dimetil
propil
trimetoxibencil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888108933T
Other languages
English (en)
Inventor
Cesare Casagrande
Francesco Santangelo
Maria Luisa Calabi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zambon Group SpA
Original Assignee
Zambon Group SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Group SpA filed Critical Zambon Group SpA
Application granted granted Critical
Publication of ES2039506T3 publication Critical patent/ES2039506T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)

Abstract

SE DESCRIBE EL COMPUESTO N,N''-DIMETIL-N-(3,4,5TRIMETOXIBENCIL)-N''-[3,3-DI(4-FUOROFENIL)-PROPIL]-ETILENDIAMINA Y SUS SALES. ESTE COMPUESTO ES UTIL EN EL TRATAMIENTO DE VARIOAS PATOLOGIAS CARDIOVASCULARES
ES198888108933T 1987-06-05 1988-06-03 Un procedimiento para la preparacion del compuesto n,n'-dimetil-n-(3,4,5-trimetoxibencil)-n'-(3,3-di-(4-fluorofenil)-propil)-etilendiamina. Expired - Lifetime ES2039506T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT20800/87A IT1205124B (it) 1987-06-05 1987-06-05 Composto attivo nella terapia carciovascolare

Publications (1)

Publication Number Publication Date
ES2039506T3 true ES2039506T3 (es) 1993-10-01

Family

ID=11172253

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888108933T Expired - Lifetime ES2039506T3 (es) 1987-06-05 1988-06-03 Un procedimiento para la preparacion del compuesto n,n'-dimetil-n-(3,4,5-trimetoxibencil)-n'-(3,3-di-(4-fluorofenil)-propil)-etilendiamina.

Country Status (12)

Country Link
US (1) US4988735A (es)
EP (1) EP0293925B1 (es)
JP (1) JP2560083B2 (es)
AT (1) ATE68474T1 (es)
AU (1) AU601283B2 (es)
CA (1) CA1329398C (es)
DE (1) DE3865531D1 (es)
ES (1) ES2039506T3 (es)
FI (1) FI89262C (es)
GR (1) GR3002925T3 (es)
IT (1) IT1205124B (es)
PT (1) PT87644B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2074946B1 (es) * 1993-07-19 1996-06-16 Ferrer Int Nuevos compuestos derivados de la 1,2-etanodiamina-n,n,n',n'-tetrasustituida.
US5407955A (en) * 1994-02-18 1995-04-18 Eli Lilly And Company Methods for lowering serum cholesterol and inhibiting smooth muscle cell proliferation, restenosis, endometriosis, and uterine fibroid disease
US7511077B2 (en) * 2005-02-09 2009-03-31 Neuromed Pharmaceuticals Ltd. Diamine calcium channel blockers

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3400155A (en) * 1963-03-01 1968-09-03 Hoechst Ag N-(1-phenyl-propyl-(2))-n-aminoethyl-(2')-diphenylamines and the salts thereof
US3321523A (en) * 1965-03-29 1967-05-23 Donau Pharmazie G M B H N-(beta-diethylamino ethyl)-n-[beta-(p-methoxy phenyl) ethyl] anilines and salts thereof
US3876702A (en) * 1968-04-26 1975-04-08 Rudolf Theodor Petersen N,n-bis-(diphenylalkyl)-alkylendiamine and their salts
FR2279383A1 (fr) * 1974-04-25 1976-02-20 Synthelabo Nouveaux derives tetrasubstitues des alcoylene-diamines, leurs sels, leur preparation et les medicaments qui en contiennent
IT1150959B (it) * 1980-06-10 1986-12-17 Simes Sostanze datate di attivita' antispastica vasale e procedimenti per la loro preparazione
IT1164389B (it) * 1983-08-05 1987-04-08 Zambon Spa Derivati n-sostituiti dell'1-(4'-alchiltiofenil)-2-ammino-1,3-propandiolo
DE3542994A1 (de) * 1985-12-05 1987-06-11 Basf Ag Basisch substituierte phenylacetaldehyde, ihre herstellung und diese enthaltende arzneimittel
GB8603765D0 (en) * 1986-02-15 1986-03-19 Beecham Wuelfung Gmbh & Co Kg Compounds
HU200591B (en) * 1986-07-11 1990-07-28 Chinoin Gyogyszer Es Vegyeszet Process for producing new diphenyl propylamine derivatives and pharmaceutical compositions comprising such compounds

Also Published As

Publication number Publication date
EP0293925B1 (en) 1991-10-16
DE3865531D1 (de) 1991-11-21
EP0293925A2 (en) 1988-12-07
JP2560083B2 (ja) 1996-12-04
CA1329398C (en) 1994-05-10
IT8720800A0 (it) 1987-06-05
ATE68474T1 (de) 1991-11-15
US4988735A (en) 1991-01-29
PT87644A (pt) 1988-07-01
AU601283B2 (en) 1990-09-06
JPS6485952A (en) 1989-03-30
IT1205124B (it) 1989-03-15
FI882644A0 (fi) 1988-06-03
PT87644B (pt) 1992-09-30
AU1691888A (en) 1988-12-08
FI89262B (fi) 1993-05-31
FI882644L (fi) 1988-12-06
GR3002925T3 (en) 1993-01-25
FI89262C (fi) 1993-09-10
EP0293925A3 (en) 1989-02-15

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