ES2043674T3 - Procedimiento de evaluacion mutagenica. - Google Patents
Procedimiento de evaluacion mutagenica.Info
- Publication number
- ES2043674T3 ES2043674T3 ES87311520T ES87311520T ES2043674T3 ES 2043674 T3 ES2043674 T3 ES 2043674T3 ES 87311520 T ES87311520 T ES 87311520T ES 87311520 T ES87311520 T ES 87311520T ES 2043674 T3 ES2043674 T3 ES 2043674T3
- Authority
- ES
- Spain
- Prior art keywords
- substance
- amino acid
- evaluation procedure
- mutagenic
- mutagenic evaluation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 2
- 230000003505 mutagenic effect Effects 0.000 title abstract 2
- 238000011156 evaluation Methods 0.000 title 1
- 231100000219 mutagenic Toxicity 0.000 title 1
- 150000001413 amino acids Chemical class 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 102000002004 Cytochrome P-450 Enzyme System Human genes 0.000 abstract 1
- 108010015742 Cytochrome P-450 Enzyme System Proteins 0.000 abstract 1
- 241000293869 Salmonella enterica subsp. enterica serovar Typhimurium Species 0.000 abstract 1
- 241000187747 Streptomyces Species 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 239000001963 growth medium Substances 0.000 abstract 1
- 231100000243 mutagenic effect Toxicity 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
- C12Q1/10—Enterobacteria
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/24—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- G01N2333/255—Salmonella (G)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/36—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Actinomyces; from Streptomyces (G)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/795—Porphyrin- or corrin-ring-containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/795—Porphyrin- or corrin-ring-containing peptides
- G01N2333/80—Cytochromes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/902—Oxidoreductases (1.)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/902—Oxidoreductases (1.)
- G01N2333/90245—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
UN METODO PARA LA EVALUACION DE LA ACTIVIDAD MUTAGENICA POTENCIAL DE UNA SUSTANCIA, QUE COMPRENDE: (A) CULTIVAR BACTERIAS INDUCIDAS P-450 DE CITOCROMO A PARTIR DEL GENERO STREPTOMICES EN UN MEDIO DE CULTIVO QUE CONTIENE LA SUSTANCIA QUE SE EVALUA; (B) INCUBAR UN AMINOACIDO QUE REQUIERE CEPA MUTANTE DE SALMONELLA TIFIMURIUM EN PRESENCIA DE UNA MUESTRA DE CULTIVO BACTERIANO PROCEDENTE DE (A); Y (C) DETERMINAR EL NUMERO DE COLONIAS QUE REVIERTEN SUFICIENTES PARA LOS AMINOACIDOS RESULTANTES.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94766986A | 1986-12-30 | 1986-12-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2043674T3 true ES2043674T3 (es) | 1994-01-01 |
Family
ID=25486538
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES87311520T Expired - Lifetime ES2043674T3 (es) | 1986-12-30 | 1987-12-30 | Procedimiento de evaluacion mutagenica. |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0273771B1 (es) |
| JP (1) | JPS63254996A (es) |
| KR (1) | KR880007717A (es) |
| AT (1) | ATE94908T1 (es) |
| AU (1) | AU618944B2 (es) |
| CA (1) | CA1313613C (es) |
| DE (1) | DE3787520T2 (es) |
| DK (1) | DK690687A (es) |
| ES (1) | ES2043674T3 (es) |
| IE (1) | IE62249B1 (es) |
| IL (1) | IL84977A (es) |
| NZ (1) | NZ223044A (es) |
| ZA (1) | ZA879727B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5213971A (en) * | 1986-12-30 | 1993-05-25 | E. I. Du Pont De Nemours And Company | Process for inducing cytochrome P-450 enzymes in Streptomyces bacteria and determining the mutagenicity of chemicals |
| US5169755A (en) * | 1986-12-30 | 1992-12-08 | E. I. Du Pont De Nemours And Company | Process for inducing cytochrome P-450 enzymes in streptomyces bacteria and determining the mutagenicity of chemicals |
| CA2128399A1 (en) | 1993-07-20 | 1995-01-21 | Koji Hayashi | Method for safety evaluation of chemical compound using recombinant yeast expressing human cytochrome p450 |
| AUPP438598A0 (en) | 1998-06-29 | 1998-07-23 | Garvan Institute Of Medical Research | NPY-Y7 receptor gene |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4352880A (en) * | 1979-09-17 | 1982-10-05 | Massachusetts Institute Of Technology | Diffusion bioassay for the quantitative determination of mutagenicity |
| FI67404C (fi) * | 1982-07-12 | 1986-07-28 | Labsystems Oy | Foerfarande foer utfoering av mutagenitettest |
| AU7793587A (en) * | 1986-09-05 | 1988-03-10 | Medical Research Council | Mammalian cell mutagenicity screening test |
| NZ223569A (en) * | 1987-02-24 | 1990-06-26 | Mobil Oil Corp | Assaying polynuclear compounds for mutagenic activity |
-
1987
- 1987-12-22 CA CA000555092A patent/CA1313613C/en not_active Expired - Fee Related
- 1987-12-22 NZ NZ223044A patent/NZ223044A/en unknown
- 1987-12-25 JP JP62327541A patent/JPS63254996A/ja active Pending
- 1987-12-29 IL IL84977A patent/IL84977A/xx not_active IP Right Cessation
- 1987-12-29 DK DK690687A patent/DK690687A/da not_active Application Discontinuation
- 1987-12-29 ZA ZA879727A patent/ZA879727B/xx unknown
- 1987-12-30 EP EP87311520A patent/EP0273771B1/en not_active Expired - Lifetime
- 1987-12-30 ES ES87311520T patent/ES2043674T3/es not_active Expired - Lifetime
- 1987-12-30 IE IE353787A patent/IE62249B1/en not_active IP Right Cessation
- 1987-12-30 DE DE87311520T patent/DE3787520T2/de not_active Expired - Fee Related
- 1987-12-30 AT AT87311520T patent/ATE94908T1/de not_active IP Right Cessation
- 1987-12-30 AU AU83135/87A patent/AU618944B2/en not_active Ceased
- 1987-12-30 KR KR1019870015401A patent/KR880007717A/ko not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP0273771A2 (en) | 1988-07-06 |
| DK690687A (da) | 1988-07-01 |
| DE3787520T2 (de) | 1994-02-10 |
| IE62249B1 (en) | 1995-01-11 |
| KR880007717A (ko) | 1988-08-29 |
| NZ223044A (en) | 1990-11-27 |
| IL84977A (en) | 1992-02-16 |
| EP0273771B1 (en) | 1993-09-22 |
| JPS63254996A (ja) | 1988-10-21 |
| DE3787520D1 (de) | 1993-10-28 |
| CA1313613C (en) | 1993-02-16 |
| AU618944B2 (en) | 1992-01-16 |
| AU8313587A (en) | 1988-06-30 |
| IL84977A0 (en) | 1988-06-30 |
| ZA879727B (en) | 1989-08-30 |
| IE873537L (en) | 1988-06-30 |
| EP0273771A3 (en) | 1991-01-23 |
| DK690687D0 (da) | 1987-12-29 |
| ATE94908T1 (de) | 1993-10-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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