ES2044598T3 - Procedimiento para la preparacion de derivados de fenil guanidinas. - Google Patents

Procedimiento para la preparacion de derivados de fenil guanidinas.

Info

Publication number
ES2044598T3
ES2044598T3 ES90909481T ES90909481T ES2044598T3 ES 2044598 T3 ES2044598 T3 ES 2044598T3 ES 90909481 T ES90909481 T ES 90909481T ES 90909481 T ES90909481 T ES 90909481T ES 2044598 T3 ES2044598 T3 ES 2044598T3
Authority
ES
Spain
Prior art keywords
derivatives
procedure
preparation
general formula
guanidinas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90909481T
Other languages
English (en)
Inventor
Csaba Huszar
Ferenc Sperber
Attila Nemeth
Peter Sarkozi
Eva Somfai
Lajosne Pali
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chinoin Private Co Ltd
Original Assignee
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt filed Critical Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Application granted granted Critical
Publication of ES2044598T3 publication Critical patent/ES2044598T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C07C233/42—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/43—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/04—Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C381/00—Compounds containing carbon and sulfur and having functional groups not covered by groups C07C301/00 - C07C337/00
    • C07C381/14—Compounds containing a carbon atom having four bonds to hetero atoms with a double bond to one hetero atom and at least one bond to a sulfur atom further doubly-bound to oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA INVENCION SE REFIERE A UN PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE GUANIDINA DE LA FORMULA GENERAL (I), DONDE R REPRESENTA UN GRUPO ALCALINO C SUB 1-4, M REPRESENTA UN ION DE HIDROGENO, DE SODIO, DE POTASIO O DE CALCIO, A REPRESENTA UN GRUPO DE -S-, -SO-, O DE -SO; DE FORMA QUE LOS DERIVADOS DE TIOCARBOAMIDA DE LA FORMULA GENERAL (II) SE OXIDEN, OPCIONALMENTE, EN PRESENCIA DE UN DISOLVENTE ORGANICO O INORGANICO Y QUE EL ACIDO SULFONICO DERIVADO DE LA FORMULA (III) QUE SE HA OBTENIDO, REACCIONE CON UN DERIVADO DE ANILINA DE LA FORMULA GENERAL (IV), OPCIONALMENTE, EN PRESENCIA DE UN DISOLVENTE ORGANICO O INORGANICO.
ES90909481T 1989-06-21 1990-06-21 Procedimiento para la preparacion de derivados de fenil guanidinas. Expired - Lifetime ES2044598T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU893154A HU205343B (en) 1989-06-21 1989-06-21 New process for producing guanidine derivatives

Publications (1)

Publication Number Publication Date
ES2044598T3 true ES2044598T3 (es) 1994-01-01

Family

ID=10962843

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90909481T Expired - Lifetime ES2044598T3 (es) 1989-06-21 1990-06-21 Procedimiento para la preparacion de derivados de fenil guanidinas.

Country Status (17)

Country Link
EP (1) EP0429619B1 (es)
KR (1) KR950002841B1 (es)
AR (1) AR247384A1 (es)
AT (1) ATE93515T1 (es)
BR (1) BR9006810A (es)
CA (1) CA2035036A1 (es)
DE (1) DE69002922T2 (es)
DK (1) DK0429619T3 (es)
ES (1) ES2044598T3 (es)
FI (1) FI910758A7 (es)
GR (1) GR1000909B (es)
HU (1) HU205343B (es)
PL (1) PL162904B1 (es)
RU (1) RU2015963C1 (es)
UA (1) UA13323A (es)
WO (1) WO1990015795A1 (es)
YU (1) YU121290A (es)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4348406A (en) * 1980-10-20 1982-09-07 Schering Corporation Novel guanidine derivatives
US4723029A (en) * 1983-09-23 1988-02-02 Schering Corporation Organic acid-substituted guanidine anthelmintics
US4781866A (en) * 1985-03-15 1988-11-01 Mcneilab, Inc. Process for producing amidine sulfonic acid intermediates for guanidines

Also Published As

Publication number Publication date
AR247384A1 (es) 1994-12-29
DE69002922T2 (de) 1993-12-16
GR1000909B (el) 1993-03-16
WO1990015795A1 (en) 1990-12-27
ATE93515T1 (de) 1993-09-15
CA2035036A1 (en) 1990-12-22
KR950002841B1 (ko) 1995-03-27
DE69002922D1 (de) 1993-09-30
FI910758A0 (fi) 1991-02-18
HU205343B (en) 1992-04-28
HUT54635A (en) 1991-03-28
PL162904B1 (pl) 1994-01-31
YU121290A (sh) 1992-09-07
RU2015963C1 (ru) 1994-07-15
EP0429619A1 (en) 1991-06-05
GR900100475A (en) 1991-11-15
DK0429619T3 (da) 1993-10-11
EP0429619B1 (en) 1993-08-25
UA13323A (uk) 1997-02-28
FI910758A7 (fi) 1991-02-18
KR920700193A (ko) 1992-02-19
BR9006810A (pt) 1991-08-06

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