ES2044788B1 - Procedimiento para la obtencion de nuevos derivados de aril-heteroaril-(n-(2-(3,4-dimetoxifenil)etil)-n-metil-3-aminopropoxi)metano y sus sales fisiologicamente aceptables correspondientes. - Google Patents

Procedimiento para la obtencion de nuevos derivados de aril-heteroaril-(n-(2-(3,4-dimetoxifenil)etil)-n-metil-3-aminopropoxi)metano y sus sales fisiologicamente aceptables correspondientes.

Info

Publication number
ES2044788B1
ES2044788B1 ES9201908A ES9201908A ES2044788B1 ES 2044788 B1 ES2044788 B1 ES 2044788B1 ES 9201908 A ES9201908 A ES 9201908A ES 9201908 A ES9201908 A ES 9201908A ES 2044788 B1 ES2044788 B1 ES 2044788B1
Authority
ES
Spain
Prior art keywords
dimetoxifenil
methyl
procedure
obtaining
acceptable salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES9201908A
Other languages
English (en)
Other versions
ES2044788A1 (es
Inventor
Vidal Ramon Merce
Constansa Jordi Frigola
Corominas Juan Pares
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Esteve Pharmaceuticals SA
Original Assignee
Laboratorios del Dr Esteve SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios del Dr Esteve SA filed Critical Laboratorios del Dr Esteve SA
Publication of ES2044788A1 publication Critical patent/ES2044788A1/es
Application granted granted Critical
Publication of ES2044788B1 publication Critical patent/ES2044788B1/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE NUEVOS DERIVADOS DEL ARIL- HETEROARIL-[N-(2-(3, 4-DIMETOXIFENIL)ETIL]-N-METIL-3-AMINOPROPO- XI]METANO Y SUS SALES FISIOLOGICAMENTE ACEPTABLES CORRESPONDIENTES. DICHOS DERIVADOS RESPONDEN A LA FORMULA GENERAL I EN DONDE RSI1 SC Y RSI2 SC, IGUALES O DIFERENTES, REPRESENTAN UN ATOMO DE HIDROGENO, UN HALOGENO, UN RADICAL ALQUILO INFERIOR O UN RADICAL ALCOXI INFERIOR, RSI3 SC REPRESENTA UN ATOMO DE HIDROGENO, UN ALQUILO INFERIOR DE 1 A 4 ATOMOS DE CARBONO, UN CICLOALQUILO O UN RADICAL ALQUENILO INFERIOR, Y HET REPRESENTA UN AZOL. COMPRENDE BIEN LA REACCION ENTRE UN COMPUESTO DE FORMULA GENERAL III CON UN COMPUESTO DE FORMULA GENERAL IV, O BIEN LA REACCION ENTRE UN COMPUESTO DE FORMULA GENERAL VII CON EL CLORHIDRATO DE N-METIL-2-(3,4-DIMETOXIFENIL) ETILAMINA. TAMBIEN COMPRENDE EL PROCEDIMIENTO DE OBTENCION DE SUS SALES FISIOLOGICAMENTE ACEPTABLES.
ES9201908A 1991-09-12 1992-09-10 Procedimiento para la obtencion de nuevos derivados de aril-heteroaril-(n-(2-(3,4-dimetoxifenil)etil)-n-metil-3-aminopropoxi)metano y sus sales fisiologicamente aceptables correspondientes. Expired - Lifetime ES2044788B1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9111261A FR2681322B1 (fr) 1991-09-12 1991-09-12 Derives d'aryl-heteroaryl-{n-[2-(3,4-dimethoxyphenyl)-ethyl]-n-methyl-3-aminopropoxy}-methane leur preparation et leur application en tant que medicaments .

Publications (2)

Publication Number Publication Date
ES2044788A1 ES2044788A1 (es) 1994-01-01
ES2044788B1 true ES2044788B1 (es) 1994-08-01

Family

ID=9416875

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9201908A Expired - Lifetime ES2044788B1 (es) 1991-09-12 1992-09-10 Procedimiento para la obtencion de nuevos derivados de aril-heteroaril-(n-(2-(3,4-dimetoxifenil)etil)-n-metil-3-aminopropoxi)metano y sus sales fisiologicamente aceptables correspondientes.

Country Status (2)

Country Link
ES (1) ES2044788B1 (es)
FR (1) FR2681322B1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6031109A (en) * 1993-06-22 2000-02-29 Knoll Aktiengesellschaft Phenoxy-, phenylthio-, benzoyl-alkyleneaminoalkylene-imidazole derivatives as therapeutic agents
GB9312893D0 (en) * 1993-06-22 1993-08-04 Boots Co Plc Therapeutic agents
ES2137136B1 (es) * 1998-05-18 2000-07-01 Esteve Labor Dr Empleo de derivados de aril (o heteroaril) azolilcarbinoles en la elaboracion de un medicamento para el tratamiento de la inflamacion neurogenica.
ES2150378B1 (es) * 1998-08-07 2001-07-01 Esteve Labor Dr Empleo de derivados de aril(o heteroaril)azolilcarbinoles en la elaboracion de un medicamento para el tratamiento de los trastornos mediados por un exceso de substancia p.
US7592362B2 (en) 2006-01-19 2009-09-22 Pfizer Limited Substituted imidazoles
GB2435826A (en) * 2006-03-09 2007-09-12 Esteve Labor Dr Use of substituted amine compounds in the treatment of food related disorders
ES2725977T3 (es) * 2014-12-15 2019-10-01 Esteve Pharmaceuticals Sa Compuestos metil-1H-pirazolalquilamínicos que tienen actividad multimodal contra el dolor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2613720B1 (fr) * 1987-04-10 1990-01-19 Esteve Labor Dr Derives d'aryl-heteroaryl carbinols avec activite analgesique
NL8700842A (es) * 1987-04-10 1988-11-01 Duphar Int Res

Also Published As

Publication number Publication date
FR2681322A1 (fr) 1993-03-19
FR2681322B1 (fr) 1993-12-17
ES2044788A1 (es) 1994-01-01

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Legal Events

Date Code Title Description
FA2A Application withdrawn

Effective date: 19940607