ES2045276T3 - Preparacion de insulina - Google Patents

Preparacion de insulina

Info

Publication number
ES2045276T3
ES2045276T3 ES89112310T ES89112310T ES2045276T3 ES 2045276 T3 ES2045276 T3 ES 2045276T3 ES 89112310 T ES89112310 T ES 89112310T ES 89112310 T ES89112310 T ES 89112310T ES 2045276 T3 ES2045276 T3 ES 2045276T3
Authority
ES
Spain
Prior art keywords
insulin preparation
administered
insulin
biodisponibilida
torrent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89112310T
Other languages
English (en)
Inventor
Leroy Arthur Campfield
Alberto Davidovich
Martin Howard Infeld
Navnit Shah
Francoise Jeanne Smith
Joel Unowsky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of ES2045276T3 publication Critical patent/ES2045276T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

LA ABSORCION EN EL TORRENTE SANGUINEO Y LA BIODISPONIBILIDA DE LA INSULINA ADMINISTRADA NO PARENTERALMENTE ES SIGNIFICATIVAMENTE REALIZADA EN PRESENCIA DE UNA CANTIDAD COADMINISTRADA DE UN ESTER GLICERIDO DE ACIDO CARBOXILICO POLIOXIETILENO GLICOL-C6 A C18.
ES89112310T 1988-07-21 1989-07-06 Preparacion de insulina Expired - Lifetime ES2045276T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US22268288A 1988-07-21 1988-07-21

Publications (1)

Publication Number Publication Date
ES2045276T3 true ES2045276T3 (es) 1994-01-16

Family

ID=22833245

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89112310T Expired - Lifetime ES2045276T3 (es) 1988-07-21 1989-07-06 Preparacion de insulina

Country Status (5)

Country Link
EP (1) EP0351651B1 (es)
JP (1) JPH0273021A (es)
AT (1) ATE94404T1 (es)
DE (1) DE68909135T2 (es)
ES (1) ES2045276T3 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69006662T2 (de) * 1989-08-21 1994-05-26 Hoffmann La Roche Insulinzubereitung für nicht-parenterale Verabreichung.
IL99699A (en) * 1990-10-10 2002-04-21 Autoimmune Inc Drug with the option of oral, intra-intestinal, or inhaled dosing for suppression of autoimmune response associated with type I diabetes
EP0533938A4 (en) * 1991-02-19 1993-06-16 Tsumura & Co. Composition for rectal administration of difficultly absorbable peptide
CA2145763A1 (en) * 1992-10-02 1994-04-14 William J. Curatolo Pharmaceutical compositions containing nonionic surfactants
GB9516268D0 (en) 1995-08-08 1995-10-11 Danbiosyst Uk Compositiion for enhanced uptake of polar drugs from the colon
WO2000033866A1 (en) * 1998-12-04 2000-06-15 Provalis Uk Limited Pharmaceutical compositions containing insulin
US20050063940A1 (en) * 2002-02-25 2005-03-24 Sveinbjorn Gizurarson Bioadhesive agent
US6855332B2 (en) 2002-07-03 2005-02-15 Lyfjathroun Hf. Absorption promoting agent
CA3083198A1 (en) 2008-03-26 2009-10-01 Oramed Ltd. Methods and compositions for oral administration of proteins
EP2300031B1 (en) 2008-05-05 2017-09-20 Oramed Ltd. Methods and compositions for oral administration of exenatide
HUP0900482A2 (en) 2009-08-03 2011-03-28 Cera Med Kft Pharmaceutical formulation for oral administration
ES2644962T3 (es) * 2012-01-03 2017-12-01 Oramed Ltd. Cápsulas que contiene composiciones líquidas basadas en aceite de agentes terapéuticos combinados para tratar la diabetes
EP4082530B1 (en) 2012-02-01 2024-04-10 Oramed Ltd. Protease inhibitor-containing compositions, compositions comprising same, and methods for producing and using same
EP2941267B1 (en) 2013-01-03 2022-11-16 Oramed Ltd. Compositions for use in treating nafld
PL3471702T3 (pl) 2016-06-20 2022-05-02 Capretto Ehf. Stabilne formulacje z lipidami bakteriobójczymi

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1554157A (en) * 1975-06-13 1979-10-17 Takeda Chemical Industries Ltd Stable insulin preparation for intra nasal administration
IL77186A0 (en) * 1985-11-29 1986-04-29 Touitou Elka Pharmaceutical insulin composition

Also Published As

Publication number Publication date
DE68909135D1 (de) 1993-10-21
EP0351651A3 (en) 1990-10-10
EP0351651A2 (en) 1990-01-24
JPH0273021A (ja) 1990-03-13
DE68909135T2 (de) 1994-04-07
ATE94404T1 (de) 1993-10-15
EP0351651B1 (en) 1993-09-15

Similar Documents

Publication Publication Date Title
AU1811788A (en) Promotion of healing of meniscal tissue
AU1394688A (en) Stable interferon complexes
DE3868037D1 (de) Pharmazeutische zusammensetzung mit verzoegerter wirkstoffabgabe.
ATE135231T1 (de) Verwendung von ''cartilage-inducing factor'' (cif) zur behandlung von hemato- oder lymphopoietischen krankheiten
DE58906676D1 (de) Ester des Retinols und/oder der Retinsäure enthaltende Aerosol-Inhalate.
ATE66614T1 (de) Insulinzubereitung fuer nicht-parenterale verabreichung.
GB8804164D0 (en) Bandage for administering physiologically active compound
ES2136618T3 (es) Cicatrizacion de heridas.
DE3876143D1 (de) Wegwerfbare infusionskassette mit pumpenkammer sowie triebwerk dafuer.
AU3073789A (en) Drug delivery using pulmonary surfactant to facilitate absorption
DE68909135D1 (de) Insulinzubereitung.
GR3001185T3 (en) Stable solid pharmaceutical composition containing ibuprofen and codeine
ATE111921T1 (de) Menschlicher kristallinischer granulocyt- koloniestimulierungsfaktor und dessen herstellung.
YU221889A (en) Process for producing new pharmaceutical mixture
DE69013557D1 (de) An Liposome gekuppelte bioaktive Verbindungen und ihre Verwendung in pharmazeutischen Zubereitungen.
ZA883744B (en) Promotion of healing of meniscal tissue
GR3004253T3 (es)
SE8204873D0 (sv) Farmaceutiska preparat, innefattande humant insulin och human c-peptid
ATE116849T1 (de) Pharmazeutische verwendung von fettsäuren.
USD323030S (en) Medical syringe for administering subcutaneous injections
MY100483A (en) Niflumic acid morpholinoethyl ester diniflumate, preparation, use in therapeutics as analgesic and anti- inflammatory
WO1988003021A3 (en) Treatment of gingivitis with ibuprofen or flurbiprofen
ATE130194T1 (de) Subkutane verabreichung des humanen choriongonadotropins.
AR241574A1 (es) Procedimiento para preparar una nueva composicion farmaceutica para tratar la insuficiencia cardiaca.
EP0351017A3 (en) Pharmaceutical composition useful for the treatment of cardiovascular diseases

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 351651

Country of ref document: ES