ES2048090A1 - Procedimiento para la obtencion de nuevos antitromboticos derivados de la cumarina. - Google Patents

Procedimiento para la obtencion de nuevos antitromboticos derivados de la cumarina.

Info

Publication number
ES2048090A1
ES2048090A1 ES9200196A ES9200196A ES2048090A1 ES 2048090 A1 ES2048090 A1 ES 2048090A1 ES 9200196 A ES9200196 A ES 9200196A ES 9200196 A ES9200196 A ES 9200196A ES 2048090 A1 ES2048090 A1 ES 2048090A1
Authority
ES
Spain
Prior art keywords
coumarin
procedures
obtainment
derived
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES9200196A
Other languages
English (en)
Other versions
ES2048090B1 (es
Inventor
Belmonte Lopez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorios Farmaceuticos Rovi SA
Original Assignee
Laboratorios Farmaceuticos Rovi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Farmaceuticos Rovi SA filed Critical Laboratorios Farmaceuticos Rovi SA
Priority to ES9200196A priority Critical patent/ES2048090B1/es
Priority to EP19920500036 priority patent/EP0553590B1/en
Priority to DE69220201T priority patent/DE69220201D1/de
Publication of ES2048090A1 publication Critical patent/ES2048090A1/es
Application granted granted Critical
Publication of ES2048090B1 publication Critical patent/ES2048090B1/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/42—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4
    • C07D311/44—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3
    • C07D311/46—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3 unsubstituted in the carbocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE NUEVOS ANTITROMBOTICOS DERIVADOS DE LA CUMARINA. DICHOS DERIVADOS RESPONDEN A LA FORMULA (I) EN DONDE Z Y R SE DEFINEN COMO SE INDICA EN LA DESCRIPCION. EL PROCEDIMIENTO COMPRENDE ACILAR 4-HIDROXI-CUMARINA CON UN CLORURO DE ACIDO DE FORMULA (II). LOS COMPUESTOS OBTENIDOS SON DE UTILIDAD COMO AGENTES ANTITROMBOTICOS EN LA PREVENCION Y EL TRATAMIENTO DE ENFERMEDADES TROMBOLITICAS Y CORONARIAS. OJO OJO FORMULA
ES9200196A 1992-01-31 1992-01-31 Procedimiento para la obtencion de nuevos antitromboticos derivados de la cumarina. Expired - Lifetime ES2048090B1 (es)

Priority Applications (3)

Application Number Priority Date Filing Date Title
ES9200196A ES2048090B1 (es) 1992-01-31 1992-01-31 Procedimiento para la obtencion de nuevos antitromboticos derivados de la cumarina.
EP19920500036 EP0553590B1 (en) 1992-01-31 1992-04-07 Antithrombotics derived from coumarin and process for obtaining them.
DE69220201T DE69220201D1 (de) 1992-01-31 1992-04-07 Antithrombotika, die sich von Cumarin ableiten, und Verfahren zu ihrer Herstellung

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9200196A ES2048090B1 (es) 1992-01-31 1992-01-31 Procedimiento para la obtencion de nuevos antitromboticos derivados de la cumarina.

Publications (2)

Publication Number Publication Date
ES2048090A1 true ES2048090A1 (es) 1994-03-01
ES2048090B1 ES2048090B1 (es) 1994-10-01

Family

ID=8275898

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9200196A Expired - Lifetime ES2048090B1 (es) 1992-01-31 1992-01-31 Procedimiento para la obtencion de nuevos antitromboticos derivados de la cumarina.

Country Status (3)

Country Link
EP (1) EP0553590B1 (es)
DE (1) DE69220201D1 (es)
ES (1) ES2048090B1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1306669B1 (it) * 1999-06-14 2001-10-02 Fidia Spa Composizioni farmaceutiche comprendenti 8-cloro-3 (beta-dietilaminoetil) -4-metil-7-etossicarbonilmetossi cumarina base e
CN105111176A (zh) * 2015-10-16 2015-12-02 南开大学 3-苯氧乙酰基-4-羟基香豆素衍生物与合成方法及应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1252088A (es) * 1966-12-13 1971-11-03
ES8106719A1 (es) * 1980-09-11 1981-09-01 Ind Farma Especial Procedimiento para la preparacion de 3(alfa-etilbencil)-4- hidroxicumarina
JPH0546666A (ja) * 1991-08-16 1993-02-26 Tokyo Electric Co Ltd 情報検索装置

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2427578A (en) * 1945-04-02 1947-09-16 Wisconsin Alumni Res Found 3-substituted 4-hydroxycoumarin and process of making it
FR6928M (es) * 1967-11-24 1969-05-05
HU177497B (en) * 1979-08-01 1981-10-28 Reanal Finomvegyszergyar Acaricide preparation further process for preparing the active materials

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1252088A (es) * 1966-12-13 1971-11-03
ES8106719A1 (es) * 1980-09-11 1981-09-01 Ind Farma Especial Procedimiento para la preparacion de 3(alfa-etilbencil)-4- hidroxicumarina
JPH0546666A (ja) * 1991-08-16 1993-02-26 Tokyo Electric Co Ltd 情報検索装置

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BASE DE DATOS WPIL, n‘ acceso 75-54824W, 1975, Derwent Publ. Ltd., London, GB & JP-A-5046666 (TORAY INDS KK) 25.04.1975 * Resumen * *

Also Published As

Publication number Publication date
ES2048090B1 (es) 1994-10-01
DE69220201D1 (de) 1997-07-10
EP0553590A1 (en) 1993-08-04
EP0553590B1 (en) 1997-06-04

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