ES2048417T3 - Medios de contraste en particulas. - Google Patents

Medios de contraste en particulas.

Info

Publication number
ES2048417T3
ES2048417T3 ES90201963T ES90201963T ES2048417T3 ES 2048417 T3 ES2048417 T3 ES 2048417T3 ES 90201963 T ES90201963 T ES 90201963T ES 90201963 T ES90201963 T ES 90201963T ES 2048417 T3 ES2048417 T3 ES 2048417T3
Authority
ES
Spain
Prior art keywords
particles
sugar alcohols
contrast means
osmoactive agent
iodinated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90201963T
Other languages
English (en)
Inventor
Gundersen
Klaveness
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare AS
Original Assignee
Nycomed Imaging AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Imaging AS filed Critical Nycomed Imaging AS
Application granted granted Critical
Publication of ES2048417T3 publication Critical patent/ES2048417T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0438—Organic X-ray contrast-enhancing agent comprising an iodinated group or an iodine atom, e.g. iopamidol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Radiology & Medical Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Glass Compositions (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Optical Modulation, Optical Deflection, Nonlinear Optics, Optical Demodulation, Optical Logic Elements (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

Un procedimiento para producir un medio de contraste, comprendiendo dicho procedimiento mezclar partículas magnéticamente sensibles y un agente osmoactivo fisiológicamente tolerable seleccionado entre sacáridos, alcoholes de azúcares, amino alcoholes de azúcares y agentes de contraste yodados para rayos X, estando dicho agente osmoactivo presente en una concentración de 10 a 800 mmoles/l.
ES90201963T 1989-07-21 1990-07-19 Medios de contraste en particulas. Expired - Lifetime ES2048417T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898916782A GB8916782D0 (en) 1989-07-21 1989-07-21 Compositions

Publications (1)

Publication Number Publication Date
ES2048417T3 true ES2048417T3 (es) 1994-03-16

Family

ID=10660461

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90201963T Expired - Lifetime ES2048417T3 (es) 1989-07-21 1990-07-19 Medios de contraste en particulas.

Country Status (13)

Country Link
US (1) US5346690A (es)
EP (2) EP0414287B1 (es)
JP (1) JPH04506970A (es)
AT (1) ATE100333T1 (es)
AU (1) AU641677B2 (es)
CA (1) CA2062949A1 (es)
DE (1) DE69006136T2 (es)
DK (1) DK0414287T3 (es)
ES (1) ES2048417T3 (es)
FI (1) FI98986C (es)
GB (1) GB8916782D0 (es)
NO (1) NO302685B1 (es)
WO (1) WO1991001147A1 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5102652A (en) * 1986-07-03 1992-04-07 Advanced Magnetics Inc. Low molecular weight carbohydrates as additives to stabilize metal oxide compositions
US5114703A (en) * 1989-05-30 1992-05-19 Alliance Pharmaceutical Corp. Percutaneous lymphography using particulate fluorocarbon emulsions
US5370901A (en) * 1991-02-15 1994-12-06 Bracco International B.V. Compositions for increasing the image contrast in diagnostic investigations of the digestive tract of patients
US5179955A (en) * 1991-02-22 1993-01-19 Molecular Biosystems, Inc. Method of abdominal ultrasound imaging
JPH06511481A (ja) * 1991-07-05 1994-12-22 ユニバーシティ オブ ロチェスター 気泡を取り込む超微小非凝集多孔質粒子
CA2182213A1 (en) * 1994-01-28 1995-08-03 William George Gorman Oral magnetic particle formulation
FR2736051B3 (fr) * 1995-06-29 1997-09-26 Guerbet Sa Complexes metalliques de polyaminoacides, leur procede de preparation et leur utilisation en imagerie diagnostique
GB9603547D0 (en) * 1996-02-20 1996-04-17 Nycomed Imaging As Contrast media
EP1031354A3 (en) 1999-01-19 2003-02-05 Rohm And Haas Company Polymeric MRI Contrast agents
ZA200404023B (en) 2001-11-21 2005-05-24 E Z Em Inc Formulations for use in medical or diagnostic procedures.
BRPI0519739A2 (pt) * 2004-12-30 2009-03-10 Cinv Ag combinaÇço compreendendo um agente fornecendo um sinal, um material de implante e uma droga
SI1836239T1 (sl) * 2005-01-13 2009-04-30 Cinv Ag Kompozitni materiali, ki vsebujejo ogljikove nanodelce
BRPI0608506A2 (pt) * 2005-03-18 2010-01-05 Cinv Ag processo para preparação de materiais metálicos porosos sinterizados
KR100695744B1 (ko) * 2005-05-03 2007-03-19 한국원자력연구소 디티피에이(ｄｔｐａ) 유도체 및 이들을 이용한 금속 착화물, 이들을 포함하는 방사선원 및 조영제
EA012091B1 (ru) * 2005-07-01 2009-08-28 Синвеншен Аг Медицинское устройство, содержащее сетчатый композиционный материал
US20100259259A1 (en) * 2005-09-21 2010-10-14 Markus Zahn Systems and methods for tuning properties of nanoparticles
AU2006303324A1 (en) * 2005-10-18 2007-04-26 Cinvention Ag Thermoset particles and methods for production thereof
US9585973B1 (en) 2008-06-05 2017-03-07 Peter Quagliano Palatable liquid dilution vehicles for oral contrast agents
DE102009054956A1 (de) * 2009-12-18 2011-06-22 Siemens Aktiengesellschaft, 80333 Magnetresonanztomographie-Bildgebung
JPWO2021172030A1 (es) * 2020-02-28 2021-09-02

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3316703A1 (de) * 1983-05-04 1984-11-08 Schering AG, 1000 Berlin und 4709 Bergkamen Orales kontrastmittel fuer die kernspintomographie und dessen herstellung
US4698302A (en) * 1983-05-12 1987-10-06 Advanced Magnetics, Inc. Enzymatic reactions using magnetic particles
CA1211147A (en) * 1984-03-27 1986-09-09 Prahlada R. Batni (Deceased) Tandem commutatorless dc machine
GB8408127D0 (en) * 1984-03-29 1984-05-10 Nyegaard & Co As Contrast agents
DE3577185D1 (de) * 1984-11-01 1990-05-23 Nycomed As Paramagnetische kontrastmittel fuer die anwendung in "in vivo" nmr-diagnostischen methoden und die herstellung davon.
SE465907B (sv) * 1984-11-01 1991-11-18 Nyegaard & Co As Diagnosticeringsmedel innehaallande en paramagnetisk metall
US5141739A (en) * 1986-07-03 1992-08-25 Advanced Magnetics, Inc. Delivery of x-ray contrast agents using receptor mediated endocytosis
DE3709851A1 (de) * 1987-03-24 1988-10-06 Silica Gel Gmbh Adsorptions Te Nmr-diagnostische fluessigkeitszusammensetzungen
US5114703A (en) * 1989-05-30 1992-05-19 Alliance Pharmaceutical Corp. Percutaneous lymphography using particulate fluorocarbon emulsions
GB8916781D0 (en) * 1989-07-21 1989-09-06 Nycomed As Compositions

Also Published As

Publication number Publication date
FI98986B (fi) 1997-06-13
DE69006136D1 (de) 1994-03-03
CA2062949A1 (en) 1991-01-22
US5346690A (en) 1994-09-13
NO302685B1 (no) 1998-04-14
AU6163390A (en) 1991-02-22
EP0414287A1 (en) 1991-02-27
WO1991001147A1 (en) 1991-02-07
FI920236A0 (fi) 1992-01-20
EP0483278A1 (en) 1992-05-06
JPH04506970A (ja) 1992-12-03
ATE100333T1 (de) 1994-02-15
EP0414287B1 (en) 1994-01-19
NO920264D0 (no) 1992-01-20
FI98986C (fi) 1997-09-25
DK0414287T3 (da) 1994-02-28
DE69006136T2 (de) 1994-05-05
GB8916782D0 (en) 1989-09-06
NO920264L (no) 1992-01-20
AU641677B2 (en) 1993-09-30

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