ES2051721T3 - Productos activos para impedir las metastasis tumorales. - Google Patents
Productos activos para impedir las metastasis tumorales.Info
- Publication number
- ES2051721T3 ES2051721T3 ES87115378T ES87115378T ES2051721T3 ES 2051721 T3 ES2051721 T3 ES 2051721T3 ES 87115378 T ES87115378 T ES 87115378T ES 87115378 T ES87115378 T ES 87115378T ES 2051721 T3 ES2051721 T3 ES 2051721T3
- Authority
- ES
- Spain
- Prior art keywords
- tumor metastasis
- active products
- prevent tumor
- prevent
- products
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 206010027476 Metastases Diseases 0.000 title abstract 2
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 230000009401 metastasis Effects 0.000 title 1
- VMVKIDPOEOLUFS-AREMUKBSSA-N (2r)-2-(3,4-dimethoxyphenyl)-5-[2-(3-methoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile Chemical compound COC1=CC=CC(CCN(C)CCC[C@@](C#N)(C(C)C)C=2C=C(OC)C(OC)=CC=2)=C1 VMVKIDPOEOLUFS-AREMUKBSSA-N 0.000 abstract 1
- XQLWNAFCTODIRK-MUUNZHRXSA-N (2r)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-yl-2-(3,4,5-trimethoxyphenyl)pentanenitrile Chemical compound C1=C(OC)C(OC)=CC=C1CCN(C)CCC[C@@](C#N)(C(C)C)C1=CC(OC)=C(OC)C(OC)=C1 XQLWNAFCTODIRK-MUUNZHRXSA-N 0.000 abstract 1
- DWAWDSVKAUWFHC-HSZRJFAPSA-N (2r)-5-[methyl(2-phenylethyl)amino]-2-phenyl-2-propan-2-ylpentanenitrile Chemical compound C([C@](C(C)C)(C#N)C=1C=CC=CC=1)CCN(C)CCC1=CC=CC=C1 DWAWDSVKAUWFHC-HSZRJFAPSA-N 0.000 abstract 1
- SGTNSNPWRIOYBX-HHHXNRCGSA-N dexverapamil Chemical compound C1=C(OC)C(OC)=CC=C1CCN(C)CCC[C@@](C#N)(C(C)C)C1=CC=C(OC)C(OC)=C1 SGTNSNPWRIOYBX-HHHXNRCGSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Abstract
SE DESCRIBE EL USO DE (+) - DEVAPAMILO, (+) - GALOPAMILO, (+) - DEVAPAMILO Y/O (+) - EMOPAMILO PARA EVITAR METASTASIS TUMORALES.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19863635931 DE3635931A1 (de) | 1986-10-22 | 1986-10-22 | Wirkstoffe zur verhuetung von tumormetastasen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2051721T3 true ES2051721T3 (es) | 1994-07-01 |
Family
ID=6312240
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES87115378T Expired - Lifetime ES2051721T3 (es) | 1986-10-22 | 1987-10-21 | Productos activos para impedir las metastasis tumorales. |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0270782B1 (es) |
| JP (1) | JPS63264414A (es) |
| AT (1) | ATE79255T1 (es) |
| AU (1) | AU607941B2 (es) |
| DE (2) | DE3635931A1 (es) |
| ES (1) | ES2051721T3 (es) |
| ZA (1) | ZA877900B (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3635930A1 (de) * | 1986-10-22 | 1988-04-28 | Basf Ag | Wirkstoffe zur anwendung bei der behandlung von tumoren |
| DE3826796A1 (de) * | 1988-08-06 | 1990-02-08 | Basf Ag | Substituierte phenylacetonitrile zur verwendung als resistenzbrecher |
| DE3928287A1 (de) * | 1989-08-26 | 1991-02-28 | Knoll Ag | Verwendung des (+)-enantiomeren von anipamil |
| AU3205497A (en) * | 1996-05-23 | 1997-12-09 | G.D. Searle & Co. | Pharmaceutical compositions containing non-racemic verapamil and process for optimizing the pharmaceutical activity of r- and s-verapamil |
| AU2001231550A1 (en) * | 2000-11-29 | 2002-06-11 | Epidauros Biotechnologie Ag | Use of mdr-1 inducers for treating or preventing diseases |
| US20030092765A1 (en) * | 2001-11-15 | 2003-05-15 | John Kelly | Treatment of abnormal increases in gastrointestinal motility with (R)-verapamil |
| JP6940950B2 (ja) * | 2014-02-10 | 2021-09-29 | アンスティテュ・キュリInstitut Curie | 細胞遊走を調節するためのMcoln−1モジュレータの使用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2059985C3 (de) * | 1970-12-05 | 1979-10-04 | Knoll Ag, 6700 Ludwigshafen | Rechtsdrehende, basisch substituierte Phenylacetonitrile, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
| US4690935A (en) * | 1983-03-31 | 1987-09-01 | Wayne State University | Inhibition of tumor growth and metastasis with calcium channel blocker compounds |
| JPH0753665B2 (ja) * | 1984-04-20 | 1995-06-07 | 財団法人癌研究会 | 抗転移剤 |
| DE3635930A1 (de) * | 1986-10-22 | 1988-04-28 | Basf Ag | Wirkstoffe zur anwendung bei der behandlung von tumoren |
-
1986
- 1986-10-22 DE DE19863635931 patent/DE3635931A1/de not_active Withdrawn
-
1987
- 1987-10-20 JP JP62262940A patent/JPS63264414A/ja active Pending
- 1987-10-21 DE DE8787115378T patent/DE3781116D1/de not_active Expired - Lifetime
- 1987-10-21 AU AU79996/87A patent/AU607941B2/en not_active Ceased
- 1987-10-21 AT AT87115378T patent/ATE79255T1/de not_active IP Right Cessation
- 1987-10-21 ES ES87115378T patent/ES2051721T3/es not_active Expired - Lifetime
- 1987-10-21 EP EP87115378A patent/EP0270782B1/de not_active Expired - Lifetime
- 1987-10-21 ZA ZA877900A patent/ZA877900B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0270782B1 (de) | 1992-08-12 |
| ATE79255T1 (de) | 1992-08-15 |
| AU607941B2 (en) | 1991-03-21 |
| JPS63264414A (ja) | 1988-11-01 |
| ZA877900B (en) | 1989-06-28 |
| DE3781116D1 (de) | 1992-09-17 |
| EP0270782A3 (en) | 1990-01-03 |
| DE3635931A1 (de) | 1988-04-28 |
| AU7999687A (en) | 1988-04-28 |
| EP0270782A2 (de) | 1988-06-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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