ES2052618T3 - Procedimiento para la preparacion de acetoacetil-arilamidas o -heteroarilamidas de compuestos aromaticos desactivados. - Google Patents

Procedimiento para la preparacion de acetoacetil-arilamidas o -heteroarilamidas de compuestos aromaticos desactivados.

Info

Publication number
ES2052618T3
ES2052618T3 ES88102229T ES88102229T ES2052618T3 ES 2052618 T3 ES2052618 T3 ES 2052618T3 ES 88102229 T ES88102229 T ES 88102229T ES 88102229 T ES88102229 T ES 88102229T ES 2052618 T3 ES2052618 T3 ES 2052618T3
Authority
ES
Spain
Prior art keywords
amine
replaced
heteroarilamidas
procedure
benzoate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88102229T
Other languages
English (en)
Inventor
Theodor Dr Papenfuhs
Wolfgang Dr Daub
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of ES2052618T3 publication Critical patent/ES2052618T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/45—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
    • C07C309/51—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/52—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of six-membered aromatic rings being part of condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE ACETOACETILARILAMINAS O HETEROARILAMIDAS DE COMPUESTOS AROMATICOS O HETEROAROMATICOS A PARTIR DE 1 MOL DE UNA AMINA DE FORMULA (I), DONDE X E Y REPRESENTAN CH O UNO DE AMBOS REPRESENTAN UN ATOMO DE HIDROGENO, R ES HIDROGENO O HALOGENO, UN GRUPO ALQUILO, BETA-HIDROXIETILO, BENCILO O FENILO OPCIONALMENTE SUSTITUIDO Y A ES UN ANILLO BENCENICO CONDENSADO, ESTANDO EL ANILLO HETEROCICLICO HEXAGONAL SUSTITUIDO CON 1 O 2 SUSTITUYENTES MAS Y PUDIENDO ESTAR SUSTITUIDO CON 1 A 3 SUSTITUYENTES EL ANILLO BENCENICO A. ESTA AMINA SE HACE REACCIONAR CON 1 A 1,2 MOLES DE DICETENA POR MOL DE AMINA A TEMPERATURAS ENTRE 20 Y 100 GRADOS C EN ACIDO ACETICO GLACIAL, EN PRESENCIA DE 1 A 20 MOLES % DE UN CATALIZADOR BASICO COMO AMINA TERCIARIA, FLUORURO, ACETATO, TRIFLUORMETANSULFONATO, TRIFLUORACETATO, BENZOATO, O-, M-, P- BENZOATO DE ALQUILO C1-C4, O-, M-, P-BENZOATO DE ALCOXILO C1-C4, U O-, M-, P-BENZOATO DE DI(ALQUIL C1-C4-AMINA) MEDIANTE ESTA REACCION SE TRANSFIERE EL SUSTITUYENTE R-NH- AL GRUPO R-N-CO-CH2-CO-CH3.
ES88102229T 1987-02-25 1988-02-16 Procedimiento para la preparacion de acetoacetil-arilamidas o -heteroarilamidas de compuestos aromaticos desactivados. Expired - Lifetime ES2052618T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3706009 1987-02-25
DE19873731912 DE3731912A1 (de) 1987-02-25 1987-09-23 Verfahren zur herstellung von acetoacetylarylamiden bzw. -heteroarylamiden desaktivierter aromaten

Publications (1)

Publication Number Publication Date
ES2052618T3 true ES2052618T3 (es) 1994-07-16

Family

ID=25852873

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88102229T Expired - Lifetime ES2052618T3 (es) 1987-02-25 1988-02-16 Procedimiento para la preparacion de acetoacetil-arilamidas o -heteroarilamidas de compuestos aromaticos desactivados.

Country Status (7)

Country Link
EP (1) EP0280156B1 (es)
KR (1) KR950013105B1 (es)
CA (1) CA1340980C (es)
DE (2) DE3731912A1 (es)
DK (1) DK95588A (es)
ES (1) ES2052618T3 (es)
MX (1) MX171862B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9121118D0 (en) * 1991-10-04 1991-11-13 Univ Manchester Analysing for akd
CN103408452A (zh) * 2013-08-19 2013-11-27 江苏隆昌化工有限公司 一种合成邻硝基对氯乙酰乙酰苯胺的绿色工艺
CN112961069B (zh) * 2021-02-08 2022-08-09 山东京博生物科技有限公司 一种对氯邻硝基乙酰乙酰苯胺的制备方法
CN113683526B (zh) * 2021-08-13 2023-06-30 山东京博农化科技股份有限公司 一种利用填充床式反应器制备对氯邻硝基乙酰乙酰苯胺的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB715896A (en) * 1951-08-27 1954-09-22 Distillers Co Yeast Ltd Production of acetoacetic acid amides
DE2519036A1 (de) * 1975-04-29 1976-11-11 Hoechst Ag Verfahren zur herstellung von acetoacetylarylamiden
EP0004611A1 (de) * 1978-03-31 1979-10-17 Ciba-Geigy Ag Verfahren zur Herstellung von Acetoacetylarylamiden
DE3046367A1 (de) * 1980-12-09 1982-07-08 Hoechst Ag, 6000 Frankfurt Verfahren zur herstellung von 1-acetoacetylamino-4-chlor-2,5-dimethoxybenzol

Also Published As

Publication number Publication date
KR950013105B1 (en) 1995-10-24
DE3875753D1 (de) 1992-12-17
CA1340980C (en) 2000-05-02
DK95588A (da) 1988-08-26
MX171862B (es) 1993-11-22
EP0280156A3 (en) 1989-10-11
DE3731912A1 (de) 1988-09-08
KR880009905A (ko) 1988-10-05
EP0280156A2 (de) 1988-08-31
EP0280156B1 (de) 1992-11-11
DK95588D0 (da) 1988-02-24

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