ES2053816T3 - Liberacion prolongada de somatotropina. - Google Patents

Liberacion prolongada de somatotropina.

Info

Publication number
ES2053816T3
ES2053816T3 ES88870047T ES88870047T ES2053816T3 ES 2053816 T3 ES2053816 T3 ES 2053816T3 ES 88870047 T ES88870047 T ES 88870047T ES 88870047 T ES88870047 T ES 88870047T ES 2053816 T3 ES2053816 T3 ES 2053816T3
Authority
ES
Spain
Prior art keywords
somatotropin
prolonged release
effective dose
parenteral
binder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88870047T
Other languages
English (en)
Inventor
Michael Joseph Azain
Thomas Richard Kasser
Kenneth Eugene Eigenberg
Milton Jerome Sabacky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Monsanto Co
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Co filed Critical Monsanto Co
Application granted granted Critical
Publication of ES2053816T3 publication Critical patent/ES2053816T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Reproductive Health (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Fodder In General (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Silicon Polymers (AREA)
  • Detergent Compositions (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

UN ARTICULO CONFORMADO ADAPTADO PARA IMPLANTACION PARENTERAL COMPRENDE UNA SOMATOTROPINA SOLIDA, ESENCIALMENTE LIBRE DE AGLOMERANTE Y DE MATRIZ, Y TIENE POR LO MENOS UNA SUPERFICIE DE LIBERACION NO RECUBIERTA PARA PROPORCIONAR LIBERACION PROLONGADA DE UNA DOSIS EFECTIVA DE UNA SOMATOTROPINA A UN ANIMAL.
ES88870047T 1987-03-16 1988-03-15 Liberacion prolongada de somatotropina. Expired - Lifetime ES2053816T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2609587A 1987-03-16 1987-03-16
US07/146,381 US4863736A (en) 1987-03-16 1988-02-03 Somatotropin prolonged release

Publications (1)

Publication Number Publication Date
ES2053816T3 true ES2053816T3 (es) 1994-08-01

Family

ID=26700778

Family Applications (2)

Application Number Title Priority Date Filing Date
ES90202047T Expired - Lifetime ES2044410T3 (es) 1987-03-16 1988-03-15 Procedimiento para la liberacion prolongada de somatotropina.
ES88870047T Expired - Lifetime ES2053816T3 (es) 1987-03-16 1988-03-15 Liberacion prolongada de somatotropina.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES90202047T Expired - Lifetime ES2044410T3 (es) 1987-03-16 1988-03-15 Procedimiento para la liberacion prolongada de somatotropina.

Country Status (24)

Country Link
US (1) US4863736A (es)
EP (2) EP0283458B1 (es)
JP (1) JP2664398B2 (es)
KR (1) KR900006886B1 (es)
CN (1) CN1051716C (es)
AT (2) ATE77558T1 (es)
AU (1) AU609456B2 (es)
BG (1) BG83325A (es)
BR (1) BR8801163A (es)
CA (1) CA1322329C (es)
DE (3) DE3872279T2 (es)
DK (1) DK139288A (es)
ES (2) ES2044410T3 (es)
FI (1) FI881219A7 (es)
GR (1) GR3005504T3 (es)
HU (1) HU208403B (es)
IE (2) IE62486B1 (es)
IL (1) IL85742A (es)
NO (1) NO881131L (es)
NZ (1) NZ223878A (es)
PL (1) PL161857B1 (es)
PT (1) PT86978B (es)
RU (1) RU2087155C1 (es)
YU (1) YU51888A (es)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5688519A (en) * 1987-04-06 1997-11-18 Leonard; Robert J. Flash-flow fused medicinal implants
US5137669A (en) * 1988-03-02 1992-08-11 Endocon, Inc. Manufacture of partially fused peptide pellet
DE68924808D1 (de) * 1988-07-26 1995-12-21 Univ Rutgers Vorrichtungen und Verfahren zur Wachstumsförderung bei Bratgeflügel.
DK173142B1 (da) * 1988-08-24 2000-02-07 Natinco Nv Fremgangsmåde til forbedring af kødkvaliteten og foderomsætningseffektiviteten for grise
US5637566A (en) * 1988-08-24 1997-06-10 Southern Cross Biotech Pty. Ltd. Method of improving carcass quality by administering growth hormone
PH30995A (en) * 1989-07-07 1997-12-23 Novartis Inc Sustained release formulations of water soluble peptides.
US5538739A (en) * 1989-07-07 1996-07-23 Sandoz Ltd. Sustained release formulations of water soluble peptides
US5182369A (en) * 1990-02-28 1993-01-26 Monsanto Company Method for purifying somatotropin monomers
US5232708A (en) * 1990-06-20 1993-08-03 Monsanto Company Coated veterinary implants
US5156851A (en) * 1990-06-20 1992-10-20 Monsanto Company Coated veterinary implants
US5091185A (en) * 1990-06-20 1992-02-25 Monsanto Company Coated veterinary implants
AU660290B2 (en) * 1990-08-09 1995-06-22 Endocon, Inc. Multiple drug delivery system
US5169834A (en) * 1990-11-30 1992-12-08 American Cyanamid Company Compositions and method for reducing vial breakage during lyophilization
US5801141A (en) * 1991-06-24 1998-09-01 American Cyanamid Company Implant compositions containing a biologically active protein, peptide or polypeptide
SG47955A1 (en) * 1991-06-24 1998-04-17 American Cyanamid Co Implant compositions containing a biologically active protein peptide or polypeptide
US5328697A (en) * 1992-02-10 1994-07-12 Mallinckrodt Veterinary, Inc. Compositions and processes for the sustained release of drugs
US5429822A (en) * 1992-03-13 1995-07-04 Cambridge Scientific, Inc. Biodegradable bursting release system
SE9303068D0 (sv) * 1993-09-21 1993-09-21 Kabi Pharmacia Ab New use
ZA949350B (en) 1994-01-25 1996-05-24 Upjohn Co Aqueous prolonged release formulation
CA2183684C (en) * 1994-02-18 2008-07-15 Richard D. Hansen Inoculation of animals with dried, pelleted biological materials
US5633000A (en) * 1994-06-23 1997-05-27 Axxia Technologies Subcutaneous implant
US5595752A (en) * 1994-07-01 1997-01-21 Monsanto Company Increasing dressing percentage and carcass weight in finishing beef cattle
US5582591A (en) * 1994-09-02 1996-12-10 Delab Delivery of solid drug compositions
US5837276A (en) * 1994-09-02 1998-11-17 Delab Apparatus for the delivery of elongate solid drug compositions
US5595760A (en) * 1994-09-02 1997-01-21 Delab Sustained release of peptides from pharmaceutical compositions
US20020111603A1 (en) 1996-12-02 2002-08-15 Societe De Conseils De Recherches Et D'application Device for local administration of solid or semi-solid formulations and delayed-release formulations for proposal parental administration and preparation process
FR2756493B1 (fr) * 1996-12-02 2001-04-13 Delab Dispositif d'administration locale de formulations solides ou semi-solides
GB2326825A (en) * 1997-04-10 1999-01-06 William Leslie Porter Bolus for supplying biologically beneficial substances to ruminant animals
JP2002504932A (ja) * 1997-06-27 2002-02-12 モンサント・カンパニー ソマトトロピンによる動物の蹄の成長促進
KR19990071255A (ko) 1998-02-28 1999-09-15 성재갑 소마토트로핀과 비타민의 합제 조성물
FR2770134B1 (fr) * 1998-10-28 2002-06-07 Delab Formulations solides ou semi-solides pour administration locale
US6488649B1 (en) 1998-11-24 2002-12-03 Edward M. Lichten Implant device
US6238706B1 (en) 1999-05-06 2001-05-29 Grofish L.L.C. Method of stimulating growth in aquatic animals using growth hormones
ATE432689T1 (de) 2002-03-04 2009-06-15 Ipsen Pharma Arzneimittelformulierungen mit verzögerter freisetzung mit einem trägerpeptid

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2517513A (en) * 1943-02-27 1950-08-01 Vaernet Carl Pharmaceutical preparation for implantation
GB885798A (en) * 1958-12-06 1961-12-28 Organon Labor Ltd Preparations of the growth hormone
US4164560A (en) * 1977-01-05 1979-08-14 Folkman Moses J Systems for the controlled release of macromolecules
US4452775A (en) * 1982-12-03 1984-06-05 Syntex (U.S.A.) Inc. Cholesterol matrix delivery system for sustained release of macromolecules
HU196714B (en) 1984-10-04 1989-01-30 Monsanto Co Process for producing non-aqueous composition comprising somatotropin
US5037806A (en) 1985-02-22 1991-08-06 Monsanto Company Biologically active method using somatotropins
EP0193917A3 (en) * 1985-03-06 1987-09-23 American Cyanamid Company Water dispersible and water soluble carbohydrate polymer compositions for parenteral administration
US4670249A (en) * 1985-04-12 1987-06-02 International Minerals & Chemical Corp. Growth-promoting compositions
US4666704A (en) * 1985-05-24 1987-05-19 International Minerals & Chemical Corp. Controlled release delivery system for macromolecules
US4786501A (en) * 1985-07-15 1988-11-22 International Minerals & Chemical Corp. Cylindrical implants for the controlled release of growth hormones
IL79681A (en) * 1985-08-12 1991-06-10 Int Minerals & Chem Corp Transition metal complexes of growth hormones and their prolonged release compositions
US4663147A (en) * 1985-09-03 1987-05-05 International Minerals & Chemical Corp. Disc-like sustained release formulation
US4765980A (en) * 1986-04-28 1988-08-23 International Minerals & Chemical Corp. Stabilized porcine growth hormone
CA1257199A (en) * 1986-05-20 1989-07-11 Paul Y. Wang Preparation containing bioactive macromolecular substance for multi-months release in vivo

Also Published As

Publication number Publication date
IL85742A0 (en) 1988-08-31
BG83325A (bg) 1993-12-24
ATE77558T1 (de) 1992-07-15
US4863736A (en) 1989-09-05
AU1311088A (en) 1988-09-15
HUT46234A (en) 1988-10-28
NO881131D0 (no) 1988-03-15
HU208403B (en) 1993-10-28
AU609456B2 (en) 1991-05-02
EP0283458B1 (en) 1992-06-24
IE62486B1 (en) 1995-02-08
NZ223878A (en) 1990-10-26
JPS63277632A (ja) 1988-11-15
ATE92769T1 (de) 1993-08-15
IL85742A (en) 1993-06-10
PT86978B (pt) 1992-06-30
DK139288A (da) 1988-09-17
PL161857B1 (pl) 1993-08-31
RU2087155C1 (ru) 1997-08-20
FI881219L (fi) 1988-09-17
DE3883254D1 (de) 1993-09-16
DK139288D0 (da) 1988-03-15
DE3872279D1 (de) 1992-07-30
IE880752L (en) 1988-09-16
CN88101301A (zh) 1988-10-05
DE3883254A1 (es) 1993-09-16
EP0403032A2 (en) 1990-12-19
EP0283458A2 (en) 1988-09-21
KR900006886B1 (ko) 1990-09-24
FI881219A7 (fi) 1988-09-17
DE3883254T2 (de) 1993-12-16
EP0403032B1 (en) 1993-08-11
IE66927B1 (en) 1996-02-07
CN1051716C (zh) 2000-04-26
ES2044410T3 (es) 1994-01-01
PT86978A (en) 1988-04-01
BR8801163A (pt) 1988-10-18
EP0283458A3 (en) 1988-12-07
FI881219A0 (fi) 1988-03-15
CA1322329C (en) 1993-09-21
DE3872279T2 (de) 1993-01-07
IE930017L (en) 1988-09-16
YU51888A (en) 1990-06-30
PL271219A1 (en) 1989-07-10
NO881131L (no) 1988-09-19
KR890012668A (ko) 1989-09-18
JP2664398B2 (ja) 1997-10-15
EP0403032A3 (en) 1990-12-27
GR3005504T3 (es) 1993-06-07

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