ES2054045T3 - Benzodiazepinas, su procedimiento e intermediarios de preparacion y sus aplicaciones en terapeutica. - Google Patents

Benzodiazepinas, su procedimiento e intermediarios de preparacion y sus aplicaciones en terapeutica.

Info

Publication number
ES2054045T3
ES2054045T3 ES89400969T ES89400969T ES2054045T3 ES 2054045 T3 ES2054045 T3 ES 2054045T3 ES 89400969 T ES89400969 T ES 89400969T ES 89400969 T ES89400969 T ES 89400969T ES 2054045 T3 ES2054045 T3 ES 2054045T3
Authority
ES
Spain
Prior art keywords
benzodiazepinas
intermediaries
therapeutics
applications
preparation procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89400969T
Other languages
English (en)
Inventor
Alain Pierre Calvet
Jean-Louis Junien
Yves Robert Alain Pascal
Xavier Bernard Louis Pascaud
Francois Joseph Roman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jouveinal SA
Original Assignee
Jouveinal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jouveinal SA filed Critical Jouveinal SA
Application granted granted Critical
Publication of ES2054045T3 publication Critical patent/ES2054045T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

BENZODIACEPINAS DE FORMULA I EN LA QUE R1 Y R2 SON H O HALOGENO, AR ES INDOLILO O FENILO Y N ES 2 O 3, SON ANTAGONISTAS DE LA COLECISTOQUININA.
ES89400969T 1988-04-25 1989-04-07 Benzodiazepinas, su procedimiento e intermediarios de preparacion y sus aplicaciones en terapeutica. Expired - Lifetime ES2054045T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8805443A FR2630440B1 (fr) 1988-04-25 1988-04-25 Benzodiazepines, leur procede et intermediaires de preparation et leurs applications en therapeutique

Publications (1)

Publication Number Publication Date
ES2054045T3 true ES2054045T3 (es) 1994-08-01

Family

ID=9365634

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89400969T Expired - Lifetime ES2054045T3 (es) 1988-04-25 1989-04-07 Benzodiazepinas, su procedimiento e intermediarios de preparacion y sus aplicaciones en terapeutica.

Country Status (19)

Country Link
US (1) US4929614A (es)
EP (1) EP0340064B1 (es)
JP (1) JP2805634B2 (es)
KR (1) KR0142328B1 (es)
AT (1) ATE86995T1 (es)
AU (1) AU618086B2 (es)
CA (1) CA1340074C (es)
DE (1) DE68905365T2 (es)
DK (1) DK172664B1 (es)
ES (1) ES2054045T3 (es)
FI (1) FI91409C (es)
FR (1) FR2630440B1 (es)
HK (1) HK95496A (es)
IE (1) IE62663B1 (es)
IS (1) IS3454A7 (es)
NO (1) NO169653C (es)
NZ (1) NZ228650A (es)
PT (1) PT90339B (es)
ZA (1) ZA892682B (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL91361A (en) * 1988-09-09 1994-10-07 Fujisawa Pharmaceutical Co Disubstituted 1,9-annelated [1,4] benzodiazepinone compounds, processes for the preparation thereof and pharmaceutical compositions containing the same
US5248679A (en) * 1988-09-09 1993-09-28 Fujisawa Pharmaceutical Co., Ltd. Tricyclic compounds
IL93401A (en) * 1989-03-08 1994-08-26 Kali Chemie Pharma Gmbh H1 - Indole - 2 - Carboxylic acid 1, 7 - Consolidated N -) 1, 4 - Benzodiazepine - 3 - Il (amides, their preparation and drugs containing them
FR2652352A1 (fr) * 1989-09-28 1991-03-29 Jouveinal Sa Benzodiazepines, leur procede et intermediaires de preparation et leurs applications en therapeutique.
CA2032427A1 (en) * 1989-12-18 1991-06-19 Mark G. Bock Benzodiazepines analogs
GB9018601D0 (en) * 1990-08-24 1990-10-10 Fujisawa Pharmaceutical Co Tricyclic compounds
US5206238A (en) * 1990-11-13 1993-04-27 Merck & Co., Inc. Cholecystokinin antagonists
CA2056809A1 (en) * 1990-12-07 1992-06-08 Mark G. Bock Benzodiazepine analogs
WO1994020143A1 (fr) * 1993-03-03 1994-09-15 Fujisawa Pharmaceutical Co., Ltd. Inhibiteur d'isomerisation optique
AU3265895A (en) * 1994-08-30 1996-03-22 Fujisawa Pharmaceutical Co., Ltd. Liposome preparation
FR2725719B1 (fr) * 1994-10-14 1996-12-06 Jouveinal Inst Rech Diazepino-indoles inhibiteurs de phosphodiesterases iv
FR2776660B1 (fr) * 1998-03-27 2000-05-12 Parke Davis Diazepino-indoles de phosphodiesterases iv
HRP990246A2 (en) 1998-08-07 2000-06-30 Du Pont Pharm Co Succinoylamino benzodiazepines as inhibitors of a beta protein production
NZ525513A (en) 1998-08-07 2004-09-24 Pont Pharmaceuticals Du Succinoylamino lactams as inhibitors of Abeta protein production
US6787112B1 (en) * 1998-08-13 2004-09-07 Symyx Technologies, Inc. Parallel reactor with internal sensing and method of using same
CN1636011A (zh) * 1998-12-24 2005-07-06 杜邦药品公司 作为Aβ蛋白产生抑制剂的琥珀酰氨基苯并二氮杂䓬
EP1222176A1 (en) * 1999-10-08 2002-07-17 Bristol-Myers Squibb Pharma Company AMINO LACTAM SULFONAMIDES AS INHIBITORS OF A$g(b) PROTEIN PRODUCTION
EP1261610A2 (en) * 2000-02-17 2002-12-04 Bristol-Myers Squibb Pharma Company Succinoylamino carbocycles and heterocycles as inhibitors of a-beta protein production
MXPA02009755A (es) * 2000-04-03 2003-03-27 Bristol Myers Squibb Pharma Co Lactamas ciclicas como inhibidores de la produccion de proteina a-beta.
US6692708B2 (en) * 2001-04-05 2004-02-17 Symyx Technologies, Inc. Parallel reactor for sampling and conducting in situ flow-through reactions and a method of using same
KR101155335B1 (ko) * 2005-01-07 2012-06-11 엘지전자 주식회사 이동통신 단말기의 멀티미디어 메시지 동작방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1332410C (en) * 1984-06-26 1994-10-11 Roger M. Freidinger Benzodiazepine analogs
IL91361A (en) * 1988-09-09 1994-10-07 Fujisawa Pharmaceutical Co Disubstituted 1,9-annelated [1,4] benzodiazepinone compounds, processes for the preparation thereof and pharmaceutical compositions containing the same
FR2652352A1 (fr) * 1989-09-28 1991-03-29 Jouveinal Sa Benzodiazepines, leur procede et intermediaires de preparation et leurs applications en therapeutique.

Also Published As

Publication number Publication date
ZA892682B (en) 1990-12-28
NZ228650A (en) 1990-12-21
US4929614A (en) 1990-05-29
NO891692L (no) 1989-10-26
JP2805634B2 (ja) 1998-09-30
DK172664B1 (da) 1999-05-10
JPH0215083A (ja) 1990-01-18
AU618086B2 (en) 1991-12-12
DE68905365T2 (de) 1993-10-14
NO169653C (no) 1992-07-22
EP0340064B1 (fr) 1993-03-17
NO169653B (no) 1992-04-13
IE891067L (en) 1989-10-25
DK197289D0 (da) 1989-04-24
HK95496A (en) 1996-06-07
DE68905365D1 (de) 1993-04-22
FI91409B (fi) 1994-03-15
AU3302589A (en) 1989-10-26
FR2630440B1 (fr) 1991-09-20
ATE86995T1 (de) 1993-04-15
DK197289A (da) 1989-10-26
FR2630440A1 (fr) 1989-10-27
EP0340064A1 (fr) 1989-11-02
IE62663B1 (en) 1995-02-22
PT90339A (pt) 1989-11-10
KR900016158A (ko) 1990-11-12
FI891952A0 (fi) 1989-04-25
CA1340074C (en) 1998-10-06
PT90339B (pt) 1994-08-31
FI91409C (fi) 1994-06-27
KR0142328B1 (ko) 1998-06-01
FI891952A7 (fi) 1989-10-26
IS3454A7 (is) 1989-10-26
NO891692D0 (no) 1989-04-24

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