ES2054612T3 - Secuencias de adn que codifican para proteinas con actividad biologica de los inhibidores husi tipo-i y procedimientos tecnologicos geneticos para la preparacion de estas proteinas. - Google Patents

Secuencias de adn que codifican para proteinas con actividad biologica de los inhibidores husi tipo-i y procedimientos tecnologicos geneticos para la preparacion de estas proteinas.

Info

Publication number
ES2054612T3
ES2054612T3 ES86117504T ES86117504T ES2054612T3 ES 2054612 T3 ES2054612 T3 ES 2054612T3 ES 86117504 T ES86117504 T ES 86117504T ES 86117504 T ES86117504 T ES 86117504T ES 2054612 T3 ES2054612 T3 ES 2054612T3
Authority
ES
Spain
Prior art keywords
proteins
husi
inhibitors
type
biological activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES86117504T
Other languages
English (en)
Inventor
Regina Heinzel
Heribert Appelhans
Hans G Gassen
Werner Machleidt
Ursula Seemueller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruenenthal GmbH
Original Assignee
Gruenenthal GmbH
Chemie Gruenenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal GmbH, Chemie Gruenenthal GmbH filed Critical Gruenenthal GmbH
Application granted granted Critical
Publication of ES2054612T3 publication Critical patent/ES2054612T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

"SECUENCIAS DE ADN QUE CODIFICAN PROTEINAS CON ACTIVIDAD BIOLOGICA INHIBIDORA DE HUSI-TYPL, PROCEDIMIENTOS DE TECNOLOGIA GENETICA PARA LA OBTENCION DE DICHAS PROTEINAS Y MEDICAMENTOS QUE LAS CONTIENEN". SE DESCRIBEN SECUENCIAS DE ADN DEL GENOMA DE MAMIFEROS, ESPECIALMENTE DEL GENOMA HUMANO, QUE CODIFICAN UNA PROTEINA CON ACTIVIDAD BIOLOGICA DE INHIBIDOR DE HUSI-TYPL. SE DESCRIBE ADEMAS LA OBTENCION POR TECNOLOGIA GENETICA DE PROTEINAS CON LA ACTIVIDAD BIOLOGICA INDICADA ASI COMO MEDICAMENTOS QUE LAS CONTIENEN.
ES86117504T 1986-01-10 1986-12-16 Secuencias de adn que codifican para proteinas con actividad biologica de los inhibidores husi tipo-i y procedimientos tecnologicos geneticos para la preparacion de estas proteinas. Expired - Lifetime ES2054612T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863600571 DE3600571A1 (de) 1986-01-10 1986-01-10 Dna-sequenzen, die fuer proteine mit der biologischen aktivitaet der husi-typi-inhibitoren codieren, gentechnologische verfahren zur herstellung dieser proteine und diese proteine enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
ES2054612T3 true ES2054612T3 (es) 1994-08-16

Family

ID=6291649

Family Applications (1)

Application Number Title Priority Date Filing Date
ES86117504T Expired - Lifetime ES2054612T3 (es) 1986-01-10 1986-12-16 Secuencias de adn que codifican para proteinas con actividad biologica de los inhibidores husi tipo-i y procedimientos tecnologicos geneticos para la preparacion de estas proteinas.

Country Status (16)

Country Link
US (1) US4845076A (es)
EP (1) EP0232523B1 (es)
JP (2) JP2533869B2 (es)
AT (1) ATE88500T1 (es)
AU (1) AU604003B2 (es)
CA (1) CA1326216C (es)
DE (2) DE3600571A1 (es)
DK (1) DK11187A (es)
ES (1) ES2054612T3 (es)
HU (1) HU204888B (es)
IE (1) IE61526B1 (es)
IL (1) IL81221A0 (es)
LT (1) LTIP1753A (es)
LV (1) LV10490B (es)
PT (1) PT84089B (es)
ZA (1) ZA87141B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5871956A (en) * 1984-12-06 1999-02-16 Amgen Inc. Recombinant methods for production of serine inhibitors and DNA sequences useful for same
US6291662B1 (en) 1984-12-05 2001-09-18 Amgen Inc. Recombinant methods for production of serine protease inhibitors and DNA sequences
US6132990A (en) * 1984-12-06 2000-10-17 Amgen Boulder Inc. Recombinant methods for production of serine protease inhibitors and DNA sequences useful for same
US5900400A (en) * 1984-12-06 1999-05-04 Amgen Inc. Serine protease inhibitor analogs
US5851983A (en) * 1987-12-28 1998-12-22 Teijin Limited Elastase inhibitory polypeptide and process for production thereof by recombinant gene technology
CA1340877C (en) * 1987-12-28 2000-01-18 Takashi Sugiyama Elastase inhibitory polypeptide and process for production thereof by recombinant gene technology
DE3841873A1 (de) * 1988-12-13 1990-06-21 Gruenenthal Gmbh Neue serinprotease-inhibitor-proteine, diese enthaltende arzneimittel, dna-sequenzen, die fuer diese proteine codieren und verfahren zur herstellung dieser proteine, arzneimittel und dna-sequenzen
IT1235349B (it) * 1988-12-23 1992-06-30 Biodata Spa Saggio immunologico per determinazioni in fase omogenea
US6869925B1 (en) * 1992-09-09 2005-03-22 Amgen Inc. Inhibition of retrovirus infection
US6017880A (en) * 1994-03-09 2000-01-25 Amgen Inc. Inhibition of retrovirus infection
FI963753L (fi) * 1994-03-23 1996-09-20 Tokyo Tanabe Co Uusi lääke hengitysteiden virustaudin hoitamiseksi
US5633227A (en) * 1994-09-12 1997-05-27 Miles, Inc. Secretory leukocyte protease inhibitor as an inhibitor of tryptase
US6544740B1 (en) 1999-07-01 2003-04-08 Reprogen, Inc. Treatment of endometriosis with antileukoprotease
EP1400247A1 (en) * 1999-07-01 2004-03-24 Reprogen, Inc. Treatment of endometriosis with antileukoprotease
US7247704B2 (en) 2000-12-18 2007-07-24 Arriva Pharmaceuticals, Inc. Multifunctional protease inhibitors and their use in treatment of disease
WO2003018620A2 (en) * 2001-08-27 2003-03-06 Les Laboratoires Aeterna Inc. Serine protease inhibitor and processes for the preparation thereof
GB2532488B (en) * 2014-11-21 2019-07-31 Univ Of The Western Cape Use of AMP1 or AMP8 to diagnose HIV infection

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62501291A (ja) * 1984-12-06 1987-05-21 サイナ−ゲン　バイオロジカルズ，インコ−ポレ−テツド 精製セリンプロテアーゼインヒビターおよびこれを含有する医薬組成物
AU591474B2 (en) * 1984-12-06 1989-12-07 Amgen, Inc. Serine protease inhibitors and methods for isolation of same
IL77227A (en) * 1984-12-06 1992-08-18 Synergen Biolog Inc Recombinant methods for production of serine protease inhibitors and methods for isolation of same

Also Published As

Publication number Publication date
IE870055L (en) 1987-07-10
ATE88500T1 (de) 1993-05-15
IL81221A0 (en) 1987-08-31
AU604003B2 (en) 1990-12-06
DK11187A (da) 1987-07-11
IE61526B1 (en) 1994-11-16
JP2659525B2 (ja) 1997-09-30
LV10490A (lv) 1995-02-20
JPH07300500A (ja) 1995-11-14
PT84089A (en) 1987-02-01
EP0232523A2 (de) 1987-08-19
LV10490B (en) 1995-10-20
CA1326216C (en) 1994-01-18
EP0232523B1 (de) 1993-04-21
JP2533869B2 (ja) 1996-09-11
AU6745287A (en) 1987-07-16
HUT43106A (en) 1987-09-28
DE3600571A1 (de) 1987-08-06
DE3688324D1 (de) 1993-05-27
PT84089B (pt) 1989-02-28
DK11187D0 (da) 1987-01-09
ZA87141B (en) 1987-08-26
HU204888B (en) 1992-02-28
LTIP1753A (en) 1995-07-25
JPS62259591A (ja) 1987-11-11
EP0232523A3 (en) 1988-12-07
US4845076A (en) 1989-07-04

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