ES2055744T3 - Empleo de un quelato metalico del acido etanolaminofosforico para profilaxis y terapia. - Google Patents

Empleo de un quelato metalico del acido etanolaminofosforico para profilaxis y terapia.

Info

Publication number
ES2055744T3
ES2055744T3 ES88710021T ES88710021T ES2055744T3 ES 2055744 T3 ES2055744 T3 ES 2055744T3 ES 88710021 T ES88710021 T ES 88710021T ES 88710021 T ES88710021 T ES 88710021T ES 2055744 T3 ES2055744 T3 ES 2055744T3
Authority
ES
Spain
Prior art keywords
acid
ethanolaminophosphoric
preparation
metal
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88710021T
Other languages
English (en)
Inventor
Gernot F Dr Koehler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dr Franz Koehler Chemie GmbH
Original Assignee
Dr Franz Koehler Chemie GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Franz Koehler Chemie GmbH filed Critical Dr Franz Koehler Chemie GmbH
Application granted granted Critical
Publication of ES2055744T3 publication Critical patent/ES2055744T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/02—Iron compounds
    • C07F15/025—Iron compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C07F13/005—Compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

SE DESCRIBE UN METALQUELATO DEL ACIDO ETANOLAMINOFOSFORICO CON LA FORMULA ESTRUCTURAL (1) EN LA QUE ME SEÑALA UN METAL ALCALINOTERREO O UN METAL DE TRANSICION ENTRE LOS QUE ESTAN MAGNESIO, CINC, COBRE, HIERRO Y MANGANO ASI COMO UN PROCESO PARA SU FABRICACION. PARA SU FABRICACION SE PREVEE UN PROCESO EN EL QUE SE MEZCLA 2 - HIDROXIETILAMINA CON UN RESTO DE ACIDO POLIFOSFORICO, CALENTANDO LA MEZCLA DESPACIO HASTA 100 (GRADOS) C A LO LARGO DE VARIAS HORAS, AÑADIENDO A UNA SOLUCION ALCALINA DEL ESTER CONSEGUIDO EL HIDROXIDO DE METAL, COLOCANDO EL PH EN 10,INTRODUCIENDO A CONTINUACION DIOXIDO DE CARBONO Y FILTRANDO EL METAL CARBONATO O EL METAL FOSFATO. EL PRINCIPIO ACTIVO PARA UN PREPARADO FARMACEUTICO PARA TRATAMIENTOS PROFILACTICOS O TERAPEUTICOS DE NEUROPATIAS CARECE DE EFECTOS SECUNDARIOS SI SE MANTIENEN LAS DOSIS PREESCRITAS.
ES88710021T 1987-08-11 1988-08-11 Empleo de un quelato metalico del acido etanolaminofosforico para profilaxis y terapia. Expired - Lifetime ES2055744T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873726721 DE3726721A1 (de) 1987-08-11 1987-08-11 Verwendung eines calcium-chelats der ethanolaminophosphorsaeure zur prophylaxe oder therapie

Publications (1)

Publication Number Publication Date
ES2055744T3 true ES2055744T3 (es) 1994-09-01

Family

ID=6333531

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88710021T Expired - Lifetime ES2055744T3 (es) 1987-08-11 1988-08-11 Empleo de un quelato metalico del acido etanolaminofosforico para profilaxis y terapia.

Country Status (5)

Country Link
US (1) US5068228A (es)
EP (1) EP0303555B1 (es)
AT (1) ATE107309T1 (es)
DE (2) DE3726721A1 (es)
ES (1) ES2055744T3 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993011231A1 (en) * 1991-12-06 1993-06-10 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Tools for the diagnosis and treatment of alzheimer's disease
USRE39300E1 (en) 1993-01-28 2006-09-19 Virginia Commonwealth University Medical College Of Virginia Inhibiting the development of tolerance to and/or dependence on an addictive substance
US5352683A (en) * 1993-03-05 1994-10-04 Virginia Commonwealth University Medical College Of Virginia Method for the treatment of chronic pain
WO1995019178A1 (en) * 1994-01-13 1995-07-20 Research Foundation For Mental Hygiene, Inc. Methods and compositions for treatment and diagnosis of alzheimer disease and other disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE930566C (de) * 1951-06-25 1955-07-18 Giorgio Ferrari Verfahren zur Herstellung von AEthanol-2-aminophosphorsaeure
LU43839A1 (es) * 1963-05-31 1963-07-31
US3644603A (en) * 1968-12-30 1972-02-22 Kendall & Co Method of making 2-aminoethyl phosphate
DE2216000A1 (de) * 1972-04-01 1973-10-11 Koehler Chemie Dr Franz Arzneimittel zur therapeutischen verwendung in der dermatologie und chirurgie

Also Published As

Publication number Publication date
EP0303555A2 (de) 1989-02-15
ATE107309T1 (de) 1994-07-15
US5068228A (en) 1991-11-26
DE3850186D1 (de) 1994-07-21
EP0303555A3 (en) 1990-05-02
DE3726721A1 (de) 1989-02-23
EP0303555B1 (de) 1994-06-15

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