ES2055759T3 - Procedimiento biosintetico para la preparacion de compuestos quimicos. - Google Patents

Procedimiento biosintetico para la preparacion de compuestos quimicos.

Info

Publication number
ES2055759T3
ES2055759T3 ES89108907T ES89108907T ES2055759T3 ES 2055759 T3 ES2055759 T3 ES 2055759T3 ES 89108907 T ES89108907 T ES 89108907T ES 89108907 T ES89108907 T ES 89108907T ES 2055759 T3 ES2055759 T3 ES 2055759T3
Authority
ES
Spain
Prior art keywords
preparation
chemical compounds
biosynthetic
procedure
biosynthetic procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89108907T
Other languages
English (en)
Inventor
Gunther Prof Dr Jung
Roland Kellner
Karl-Dieter Prof Dr Entain
Norbert Schnell
Cortina Kaletta
Friedrich Prof-Dr Gotz
Rolf G Dr Werner
Hermann Dr Allgaier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Application granted granted Critical
Publication of ES2055759T3 publication Critical patent/ES2055759T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

Abstract

SE TRATA DE UN METODO BASADO EN LA RECOMBINACION PARA LA PREPARACION DE POLIPEPTIDOS QUE CONTENGAN AL MENOS UN ACIDO DEHIDROAMINO, O AL MENOS UN PUENTE LANTIONINA, DE MODO QUE EL POLIPEPTIDO ES AGENO AL HUESPED, Y BESTE PROPORCIONA UN COMPLEJO MULTIENZIMATICO CAPAZ DE EFECTUAR LA ELIMINACION DEL AGUA Y/O LA FORMACION DE PUENTES SULFURO.
ES89108907T 1988-05-18 1989-05-18 Procedimiento biosintetico para la preparacion de compuestos quimicos. Expired - Lifetime ES2055759T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888811761A GB8811761D0 (en) 1988-05-18 1988-05-18 Biosynthetic process for preparation of chemical compounds

Publications (1)

Publication Number Publication Date
ES2055759T3 true ES2055759T3 (es) 1994-09-01

Family

ID=10637101

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89108907T Expired - Lifetime ES2055759T3 (es) 1988-05-18 1989-05-18 Procedimiento biosintetico para la preparacion de compuestos quimicos.

Country Status (6)

Country Link
EP (1) EP0342658B1 (es)
JP (2) JP3267965B2 (es)
AT (1) ATE105584T1 (es)
DE (1) DE68915204T2 (es)
ES (1) ES2055759T3 (es)
GB (1) GB8811761D0 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5837485A (en) * 1988-05-18 1998-11-17 Dr. Karl Tomae Gmbh DNA encoding and biosynthetic process for the preparation of chemical compounds, lantibiotics
GB2254852B (en) * 1991-04-11 1995-04-05 Thomae Gmbh Dr K Lantibiotic isolation and purification by plural chromatography processes
CA2081704C (en) * 1991-10-31 2007-05-01 Karl-Dieter Entian Biosynthetic process for the preparation of lantibiotics
US5962253A (en) * 1996-05-13 1999-10-05 Boehringer Ingelheim International Gmbh Oxidative decarboxylation of peptides catalyzed by flavoprotein EpiD
US6861236B2 (en) 2002-05-24 2005-03-01 Applied Nanosystems B.V. Export and modification of (poly)peptides in the lantibiotic way

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4716115A (en) * 1983-09-06 1987-12-29 Microlife Technics, Inc. Derived nisin producing microorganisms, method of production and use and products obtained thereby
US4766066A (en) * 1984-09-27 1988-08-23 Eli Lilly And Company Method of using bacteriophage lambda p1 promoter to produce a functional polypeptide in streptomyces
GB8517071D0 (en) * 1985-07-05 1985-08-14 Hoffmann La Roche Gram-positive expression control sequence
GB8811760D0 (en) * 1988-05-18 1988-06-22 Thomae Gmbh Dr K Antibiotic

Also Published As

Publication number Publication date
GB8811761D0 (en) 1988-06-22
EP0342658B1 (en) 1994-05-11
JP3267965B2 (ja) 2002-03-25
EP0342658A1 (en) 1989-11-23
ATE105584T1 (de) 1994-05-15
JP2002176978A (ja) 2002-06-25
JP3350533B2 (ja) 2002-11-25
DE68915204D1 (de) 1994-06-16
JPH02107191A (ja) 1990-04-19
DE68915204T2 (de) 1994-10-27

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