ES2056074T3 - Procedimiento inmunoquimico y reactivo para la determinacion de un antigeno polivalente en una muestra liquida. - Google Patents

Procedimiento inmunoquimico y reactivo para la determinacion de un antigeno polivalente en una muestra liquida.

Info

Publication number
ES2056074T3
ES2056074T3 ES88106763T ES88106763T ES2056074T3 ES 2056074 T3 ES2056074 T3 ES 2056074T3 ES 88106763 T ES88106763 T ES 88106763T ES 88106763 T ES88106763 T ES 88106763T ES 2056074 T3 ES2056074 T3 ES 2056074T3
Authority
ES
Spain
Prior art keywords
antigen
multipurpose
determination
immunochemical
liquid sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88106763T
Other languages
English (en)
Inventor
Werner Dr Stock
Manfred Dr Baier
Klaus Peter Dr Kaspar
Peter Dr Kirch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Application granted granted Critical
Publication of ES2056074T3 publication Critical patent/ES2056074T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/824—Immunological separation techniques

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

PARA DETERMINACION CUANTITATIVA DE UN ANTIGENO POLIVALENTE SE HACE UNA PRUEBA DE TRES RECEPTORES DIFERENTES, DE LOS QUE EL PRIMERO (R1) Y EL TERCERO (R3) ESTAN DISUELTOS EN LA FASE LIQUIDA Y PUEDEN UNIRSE CON EL ANTIGENO, EL SEGUNDO RECEPTOR (R2) ESTA EN LA FASE SOLIDA Y PUEDE UNIRSE CON (R1) Y (R3) LLEVA UNA MARCA Y CON (R1) Y (R2) NO REACCIONA EN CIRCUITO, SE SEPARA LA FASE SOLIDA DE LA LIQUIDA Y SE MIDE LA MARCA EN UNA DE LAS FASES, CON LO QUE SE UTILIZA UN PRIMER RECEPTOR (R1) QUE SE COMPONE AL MENOS DE DOS MOLECULAS DE ANTICUERPOS UNIDAS UNA CON OTRA O DE FRAGMENTOS DE MOLECULAS DE ANTICUERPOS, DE LOS QUE AL MENOS UNO FORMA ESPECIFICAMENTE UNO CON EL ANTIGENO A DETERMINAR.
ES88106763T 1987-04-28 1988-04-27 Procedimiento inmunoquimico y reactivo para la determinacion de un antigeno polivalente en una muestra liquida. Expired - Lifetime ES2056074T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873714147 DE3714147A1 (de) 1987-04-28 1987-04-28 Immunchemisches verfahren und reagenz zur bestimmung eines polyvalenten antigens in einer fluessigen probe

Publications (1)

Publication Number Publication Date
ES2056074T3 true ES2056074T3 (es) 1994-10-01

Family

ID=6326435

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88106763T Expired - Lifetime ES2056074T3 (es) 1987-04-28 1988-04-27 Procedimiento inmunoquimico y reactivo para la determinacion de un antigeno polivalente en una muestra liquida.

Country Status (7)

Country Link
US (1) US4885255A (es)
EP (1) EP0289003B1 (es)
JP (1) JPH0731203B2 (es)
KR (1) KR900008958B1 (es)
AT (1) ATE108023T1 (es)
DE (2) DE3714147A1 (es)
ES (1) ES2056074T3 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3922960A1 (de) * 1989-07-12 1991-01-17 Boehringer Mannheim Gmbh Verfahren zur bestimmung eines analyten
US5648218A (en) * 1993-02-12 1997-07-15 Sealite Sciences, Inc. Preparation of photoprotein conjugates and methods of use thereof
WO1994018342A1 (en) * 1993-02-12 1994-08-18 Sealite Sciences, Inc. Preparation of photoprotein conjugates and methods of use thereof
US5556759A (en) * 1993-08-02 1996-09-17 Beach; Peter G. Assay and method for determining newborn risk for sudden infant death syndrome
DE19621133A1 (de) * 1996-05-24 1997-11-27 Boehringer Mannheim Gmbh Bestimmungsverfahren mit oligomerisierten Rezeptoren
US20040018577A1 (en) * 2002-07-29 2004-01-29 Emerson Campbell John Lewis Multiple hybrid immunoassay
RU2271006C1 (ru) * 2004-07-19 2006-02-27 Липецкий Государственный Технический Университет (Лгту) Способ детектирования сульфаметоксазола с помощью пьезокварцевого иммуносенсора
US9233382B2 (en) * 2006-07-27 2016-01-12 Ossian, Inc. Liquid spraying apparatus

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE337223B (es) * 1967-05-23 1971-08-02 Pharmacia Ab
US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4433059A (en) * 1981-09-08 1984-02-21 Ortho Diagnostic Systems Inc. Double antibody conjugate
DE3225027A1 (de) * 1982-07-05 1984-01-05 Boehringer Mannheim Gmbh, 6800 Mannheim Immunchemisches messverfahren
DE3377531D1 (en) * 1982-09-29 1988-09-01 Serono Diagnostics Ltd Immunoassay of antigens
US4659678A (en) * 1982-09-29 1987-04-21 Serono Diagnostics Limited Immunoassay of antigens
DE3345748A1 (de) * 1983-12-17 1985-08-29 Boehringer Mannheim Gmbh, 6800 Mannheim Phenolsulfonphthaleinyl-ss-d-galactoside, verfahren zu deren herstellung sowie deren verwendung zur bestimmung der ss-d-galactosidase
DE3425008A1 (de) * 1984-07-06 1986-02-06 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren und vorrichtung zur durchfuehrung analytischer bestimmungen
IL73938A (en) * 1984-01-02 1989-09-28 Boehringer Mannheim Gmbh Process and reagent for the determination of polyvalent antigen by incubation with three different receptors
DE3400027A1 (de) * 1984-01-02 1985-07-18 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur bestimmung eines polyvalenten antigens und reagenz hierfuer
US4657853A (en) * 1984-09-14 1987-04-14 E. I. Du Pont De Nemours And Company Immunoassays utilizing covalent conjugates of polymerized enzyme and antibody
JPH0656383B2 (ja) * 1985-02-22 1994-07-27 オリンパス光学工業株式会社 酵素免疫学的自動分析装置
NL8501219A (nl) * 1985-04-29 1986-11-17 Stichting Vrienden Van De Stic Immunologisch complex, de bereiding en toepassing daarvan.

Also Published As

Publication number Publication date
US4885255A (en) 1989-12-05
EP0289003A3 (de) 1991-04-10
EP0289003A2 (de) 1988-11-02
JPS63284470A (ja) 1988-11-21
DE3850439D1 (de) 1994-08-04
KR900008958B1 (ko) 1990-12-15
JPH0731203B2 (ja) 1995-04-10
ATE108023T1 (de) 1994-07-15
EP0289003B1 (de) 1994-06-29
KR880013013A (ko) 1988-11-29
DE3714147A1 (de) 1988-11-17

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