ES2057324T3 - Procedimiento para la separacion de enantiomeros de derivados del benzopirano. - Google Patents
Procedimiento para la separacion de enantiomeros de derivados del benzopirano.Info
- Publication number
- ES2057324T3 ES2057324T3 ES90120301T ES90120301T ES2057324T3 ES 2057324 T3 ES2057324 T3 ES 2057324T3 ES 90120301 T ES90120301 T ES 90120301T ES 90120301 T ES90120301 T ES 90120301T ES 2057324 T3 ES2057324 T3 ES 2057324T3
- Authority
- ES
- Spain
- Prior art keywords
- enantiomers
- separation
- procedure
- benzopirane
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
Abstract
LA INVENCION SE REFIERE A UN PROCEDIMIENTO PARA LA SEPARACION DE ENANTIOMEROS DE 3, 4-EPOXI-3, 4-DIHIDRO-2, 2-DIMETIL-3-R-2H-1-BENZOPIRANO-6 -CARBONITRILENO (I), EN EL QUE R SIGNIFICA H O CH SUB 3, CARACTERIZADO PORQUE I RACEMICO SE DISUELVE JUNTO CON UNA PEQUEÑA CANTIDAD DE (-)-I [O BIEN (+)-I] EN UN DISOLVENTE INERTE O MEZCLA DE DISOLVENTES, LA SOLUCION SE INYECTA CON (-)-I [O BIEN (+)-I], SE AISLA EL (+)-I [O BIEN (-)-I] PRECIPITADO, EN EL FILTRADO SE DISUELVE OTRO I RACEMICO, SE INYECTA CON (+)-I [O BIEN (-)-I], SE AISLA EL (+)-I [O BIEN (-)-I] PRECIPITADO Y, SI SE DESEA, SE REPITE ESTE CICLO DE CRISTALIZACION UNA O MAS VECES.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3936616A DE3936616A1 (de) | 1989-11-03 | 1989-11-03 | Verfahren zur enantiomerentrennung von benzopyranderivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2057324T3 true ES2057324T3 (es) | 1994-10-16 |
Family
ID=6392797
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES90120301T Expired - Lifetime ES2057324T3 (es) | 1989-11-03 | 1990-10-23 | Procedimiento para la separacion de enantiomeros de derivados del benzopirano. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5103025A (es) |
| EP (1) | EP0425980B1 (es) |
| JP (1) | JPH03153691A (es) |
| KR (1) | KR910009709A (es) |
| AR (1) | AR246266A1 (es) |
| AT (1) | ATE109124T1 (es) |
| AU (1) | AU630760B2 (es) |
| CA (1) | CA2029107A1 (es) |
| DE (2) | DE3936616A1 (es) |
| DK (1) | DK0425980T3 (es) |
| ES (1) | ES2057324T3 (es) |
| FI (1) | FI905440A7 (es) |
| HU (1) | HU206357B (es) |
| IE (1) | IE64627B1 (es) |
| IL (1) | IL96224A (es) |
| NO (1) | NO174713C (es) |
| NZ (1) | NZ235941A (es) |
| PT (1) | PT95774B (es) |
| YU (1) | YU47802B (es) |
| ZA (1) | ZA908816B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0430621A3 (en) * | 1989-11-29 | 1992-03-04 | Beecham Group P.L.C. | Process for the preparation of chiral 3,4-epoxy benzopyrans |
| KR100547166B1 (ko) * | 2003-04-11 | 2006-01-26 | 허윤석 | 개량형 단단문합기 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4916426B1 (es) * | 1968-09-30 | 1974-04-22 | ||
| FR2615191B1 (fr) * | 1987-05-16 | 1991-01-11 | Sandoz Sa | Nouveaux benzo(b)pyrannes et pyrannopyridines, leur preparation et leur utilisation comme medicaments |
| DE3811017A1 (de) * | 1988-03-31 | 1989-10-19 | Hoechst Ag | Ungesaettigte n-benzopyranyllactame |
| AU628331B2 (en) * | 1988-05-06 | 1992-09-17 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Chroman derivatives |
| DE3904496A1 (de) * | 1989-02-15 | 1990-08-16 | Merck Patent Gmbh | Verfahren zur enantiomerentrennung eines benzopyranderivats |
| EP0430621A3 (en) * | 1989-11-29 | 1992-03-04 | Beecham Group P.L.C. | Process for the preparation of chiral 3,4-epoxy benzopyrans |
-
1989
- 1989-11-03 DE DE3936616A patent/DE3936616A1/de not_active Withdrawn
-
1990
- 1990-10-05 YU YU189090A patent/YU47802B/sh unknown
- 1990-10-23 ES ES90120301T patent/ES2057324T3/es not_active Expired - Lifetime
- 1990-10-23 EP EP90120301A patent/EP0425980B1/de not_active Expired - Lifetime
- 1990-10-23 DE DE59006582T patent/DE59006582D1/de not_active Expired - Fee Related
- 1990-10-23 DK DK90120301.8T patent/DK0425980T3/da active
- 1990-10-23 AT AT90120301T patent/ATE109124T1/de not_active IP Right Cessation
- 1990-10-30 JP JP2290986A patent/JPH03153691A/ja active Pending
- 1990-10-30 KR KR1019900017426A patent/KR910009709A/ko not_active Ceased
- 1990-11-01 CA CA002029107A patent/CA2029107A1/en not_active Abandoned
- 1990-11-02 FI FI905440A patent/FI905440A7/fi not_active Application Discontinuation
- 1990-11-02 AU AU65787/90A patent/AU630760B2/en not_active Ceased
- 1990-11-02 NO NO904773A patent/NO174713C/no unknown
- 1990-11-02 IL IL9622490A patent/IL96224A/en not_active IP Right Cessation
- 1990-11-02 PT PT95774A patent/PT95774B/pt not_active IP Right Cessation
- 1990-11-02 IE IE396790A patent/IE64627B1/en not_active IP Right Cessation
- 1990-11-02 HU HU907006A patent/HU206357B/hu not_active IP Right Cessation
- 1990-11-02 US US07/608,442 patent/US5103025A/en not_active Expired - Fee Related
- 1990-11-02 AR AR90318276A patent/AR246266A1/es active
- 1990-11-02 ZA ZA908816A patent/ZA908816B/xx unknown
- 1990-11-02 NZ NZ235941A patent/NZ235941A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO904773L (no) | 1991-05-06 |
| HU206357B (en) | 1992-10-28 |
| EP0425980A1 (de) | 1991-05-08 |
| AU6578790A (en) | 1991-05-09 |
| NZ235941A (en) | 1992-03-26 |
| US5103025A (en) | 1992-04-07 |
| DE3936616A1 (de) | 1991-05-08 |
| DK0425980T3 (da) | 1994-08-22 |
| JPH03153691A (ja) | 1991-07-01 |
| FI905440A7 (fi) | 1991-05-04 |
| IE64627B1 (en) | 1995-08-23 |
| NO174713B (no) | 1994-03-14 |
| YU47802B (sr) | 1996-01-09 |
| AR246266A1 (es) | 1994-07-29 |
| NO174713C (no) | 1994-06-22 |
| FI905440A0 (fi) | 1990-11-02 |
| PT95774B (pt) | 1997-11-28 |
| HUT58740A (en) | 1992-03-30 |
| IE903967A1 (en) | 1991-05-08 |
| IL96224A (en) | 1995-03-15 |
| DE59006582D1 (de) | 1994-09-01 |
| IL96224A0 (en) | 1991-08-16 |
| AU630760B2 (en) | 1992-11-05 |
| CA2029107A1 (en) | 1991-05-04 |
| HU907006D0 (en) | 1991-05-28 |
| ATE109124T1 (de) | 1994-08-15 |
| NO904773D0 (no) | 1990-11-02 |
| PT95774A (pt) | 1991-09-13 |
| EP0425980B1 (de) | 1994-07-27 |
| ZA908816B (en) | 1991-09-25 |
| YU189090A (sh) | 1992-09-07 |
| KR910009709A (ko) | 1991-06-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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