ES2058023A1 - Derivados del acido 4-hidroxi-butirico. - Google Patents

Derivados del acido 4-hidroxi-butirico.

Info

Publication number
ES2058023A1
ES2058023A1 ES09202177A ES9202177A ES2058023A1 ES 2058023 A1 ES2058023 A1 ES 2058023A1 ES 09202177 A ES09202177 A ES 09202177A ES 9202177 A ES9202177 A ES 9202177A ES 2058023 A1 ES2058023 A1 ES 2058023A1
Authority
ES
Spain
Prior art keywords
hydroxybutyric acid
ch2oh
treatment
derivatives
carbons
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09202177A
Other languages
English (en)
Other versions
ES2058023B1 (es
Inventor
Gernot Kohler
Anita Kohler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dr Franz Koehler Chemie GmbH
Original Assignee
Dr Franz Koehler Chemie GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Franz Koehler Chemie GmbH filed Critical Dr Franz Koehler Chemie GmbH
Priority to ES9202177A priority Critical patent/ES2058023B1/es
Publication of ES2058023A1 publication Critical patent/ES2058023A1/es
Application granted granted Critical
Publication of ES2058023B1 publication Critical patent/ES2058023B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

DERIVADOS DEL ACIDO 4-HIDROXIBUTIRICO, DE FORMULAS I Y II, EN DONDE RSI1 SC, RSI2 SC Y RSI3 SC SIGNIFICAN LOS RADICALES H-, CHSI3 SC-, CSI2 SCHSI5 SC-, CHSI2 SCOH-CHSI2 SC-, O CHSI2 SCOH-CHOH-CHSI2 SC-, O CON EL NITROGENO FORMAN UN HETEROCICLOALCANO CON 4 O 5 CARBONOS, SIENDO RSI4 SC UN ALCOHOL O POLIALCOHOL CON 1-5 CARBONOS Y 1-5 OXIGENOS, LINEAL O RAMIFICADO, O EN FORMA DE ANILLO, Y RSI1 SC Y RSI4 SC PUEDEN ESTAR CONDENSADOS ENTRE SI PARA FORMAR UN ETER CICLICO, Y RSI5 SC Y RSI6 SC INDEPENDIENTEMENTE SON H- O CHSI2 SCOH-. LAS SALES O AMIDAS DEL ACIDO GAMMAHIDROXIBUTIRICO SE OBTIENEN POR REACCION DE GAMMA-BUTIROLACTONA CON UN AMINOALCOHOL O UN DERIVADO DE LA MORFOLINA, AJUSTANDO EL PH A 7,5. ESTOS COMPUESTOS SE USAN EN PREPARACIONES PARENTERALES U ORALES PARA LA NARCOSIS EN LA ANESTESIA, PARA LA INDUCCION AL SUEÑO O SEDACION, PARA LA TERAPIA DE LA DESINTOXICACION ALCOHOLICA, PARA LA TERAPIA DE LA CATAPLEJIA O NARCOLEPSIA, Y PARA LA TERAPIA DE TRASTORNOS DEL SUEÑO.
ES9202177A 1992-10-29 1992-10-29 Derivados del acido 4-hidroxi-butirico. Expired - Fee Related ES2058023B1 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES9202177A ES2058023B1 (es) 1992-10-29 1992-10-29 Derivados del acido 4-hidroxi-butirico.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9202177A ES2058023B1 (es) 1992-10-29 1992-10-29 Derivados del acido 4-hidroxi-butirico.

Publications (2)

Publication Number Publication Date
ES2058023A1 true ES2058023A1 (es) 1994-10-16
ES2058023B1 ES2058023B1 (es) 1995-10-01

Family

ID=8278609

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9202177A Expired - Fee Related ES2058023B1 (es) 1992-10-29 1992-10-29 Derivados del acido 4-hidroxi-butirico.

Country Status (1)

Country Link
ES (1) ES2058023B1 (es)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4143159A (en) * 1976-07-12 1979-03-06 Henkel Kommanditgesellschaft Auf Aktien Skin-care agents containing hydroxyalkyl carboxamides and process
ES8306360A1 (es) * 1980-07-17 1983-06-01 Klosa Josef Procedimiento para la preparacion de sales no higroscopicas del acido 4-hidroxibutirico.
EP0398272A1 (en) * 1989-05-19 1990-11-22 Kao Corporation Amide derivatives and dermatologic preparations containing the same
WO1992019581A1 (de) * 1991-04-29 1992-11-12 Dr. Franz Köhler Chemie GmbH Derivate der 4-hydroxy-buttersäure

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4143159A (en) * 1976-07-12 1979-03-06 Henkel Kommanditgesellschaft Auf Aktien Skin-care agents containing hydroxyalkyl carboxamides and process
ES8306360A1 (es) * 1980-07-17 1983-06-01 Klosa Josef Procedimiento para la preparacion de sales no higroscopicas del acido 4-hidroxibutirico.
EP0398272A1 (en) * 1989-05-19 1990-11-22 Kao Corporation Amide derivatives and dermatologic preparations containing the same
WO1992019581A1 (de) * 1991-04-29 1992-11-12 Dr. Franz Köhler Chemie GmbH Derivate der 4-hydroxy-buttersäure

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
S. BUDAVARI et al.: "The Merck Index, an encyclopedia of Chemicals, Drugs and Biologicals", 11 edición, 1989, Merck & Co., Inc., Rahway, NJ, US, pág. 1365, parágrafo 8603 *

Also Published As

Publication number Publication date
ES2058023B1 (es) 1995-10-01

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