ES2058793T3 - Material compuesto de pantotenato calcico. - Google Patents
Material compuesto de pantotenato calcico.Info
- Publication number
- ES2058793T3 ES2058793T3 ES90304169T ES90304169T ES2058793T3 ES 2058793 T3 ES2058793 T3 ES 2058793T3 ES 90304169 T ES90304169 T ES 90304169T ES 90304169 T ES90304169 T ES 90304169T ES 2058793 T3 ES2058793 T3 ES 2058793T3
- Authority
- ES
- Spain
- Prior art keywords
- calcium pantothenate
- ingredients
- composite
- stable
- composite material
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- FAPWYRCQGJNNSJ-UBKPKTQASA-L calcium D-pantothenic acid Chemical compound [Ca+2].OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O.OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O FAPWYRCQGJNNSJ-UBKPKTQASA-L 0.000 title abstract 4
- 229960002079 calcium pantothenate Drugs 0.000 title abstract 4
- 239000002131 composite material Substances 0.000 title abstract 3
- 239000004615 ingredient Substances 0.000 abstract 3
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 1
- MKJXYGKVIBWPFZ-UHFFFAOYSA-L calcium lactate Chemical compound [Ca+2].CC(O)C([O-])=O.CC(O)C([O-])=O MKJXYGKVIBWPFZ-UHFFFAOYSA-L 0.000 abstract 1
- 229960002401 calcium lactate Drugs 0.000 abstract 1
- 239000001527 calcium lactate Substances 0.000 abstract 1
- 235000011086 calcium lactate Nutrition 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 229910052749 magnesium Inorganic materials 0.000 abstract 1
- 229960004658 magnesium lactate Drugs 0.000 abstract 1
- 239000000626 magnesium lactate Substances 0.000 abstract 1
- 235000015229 magnesium lactate Nutrition 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000003860 storage Methods 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
- Fodder In General (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
UN COMPUESTO EL CUAL ES OBTENIBLE MEZCLANDO PANTOTENATO DE CALCIO CON UN LACTATO O CARBONATO DE CALCIO O DE MAGNESIO BASICO O NEUTRAL POR SI MISMO, EN PRESENCIA DE AGUA Y/O UN ALCOHOL INFERIOR, Y SECANDO LA MEZCLA RESULTANTE, ES ESTABLE SIN QUE SE REDUZCA EL CONTENIDO DE PANTOTENATO CALCICO DURANTE EL ALMACENAMIENTO. CUANDO OTRAS DROGAS, LAS CUALES PUEDEN CAUSAR CAMBIOS COMO RESULTADO DE COMBINACION CON PANTOTENATO CALCICO, SE COMBINAN PARA PRODUCIR VARIOS PREPARADOS, LOS COMPUESTOS SON ESTABLES PORQUE SON DIFICILMENTE AFECTADOS POR OTROS INGREDIENTES Y DIFICILMENTE AFECTAN A OTROS INGREDIENTES; POR EJEMPLO, EN PRODUCCION DE TABLETAS, POLVOS, GRANULOS, Y CAPSULAS, NO SE REQUIEREN COMPLICADOS PROCESOS PARA SEPARARLE DE OTROS INGREDIENTES, Y SE PUEDE REDUCIR DE FORMA IMPORTANTE LA EXCESIVA CANTIDAD PERDIDA CON EL TIEMPO DE LOS PROCEDIMIENTOS CONOCIDOS.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9963789 | 1989-04-19 | ||
| JP17944089 | 1989-07-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2058793T3 true ES2058793T3 (es) | 1994-11-01 |
Family
ID=26440747
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES90304169T Expired - Lifetime ES2058793T3 (es) | 1989-04-19 | 1990-04-19 | Material compuesto de pantotenato calcico. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5089276A (es) |
| EP (1) | EP0394022B1 (es) |
| JP (1) | JP2891744B2 (es) |
| AT (1) | ATE91412T1 (es) |
| DE (1) | DE69002186T2 (es) |
| DK (1) | DK0394022T3 (es) |
| ES (1) | ES2058793T3 (es) |
| HU (1) | HU208626B (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2252905B (en) * | 1991-02-11 | 1995-05-10 | Leung Lit Hung | An agent for correcting a deficiency of androgenic steroids |
| AU1798300A (en) | 1998-12-25 | 2000-07-31 | Fuji Chemical Industries, Ltd. | Method for producing calcium pantothenate |
| US8232081B2 (en) * | 1999-09-21 | 2012-07-31 | Basf Se | Methods and microorganisms for production of panto-compounds |
| US6509496B1 (en) | 2000-10-19 | 2003-01-21 | Nutrapure, Inc. | Process for making mineral, food or pharmaceutical grade salt products |
| US6887492B2 (en) | 2000-12-14 | 2005-05-03 | Leiner Health Services Corp. | Magnesium plus interactive agent delivery |
| JP4841130B2 (ja) * | 2004-10-12 | 2011-12-21 | 武田薬品工業株式会社 | 安定化されたビタミン製剤 |
| JP4615470B2 (ja) | 2006-03-29 | 2011-01-19 | 卓郎 簑和田 | 大脳の認知力を用いた疾患治療・予防の方法および医薬 |
| MX298012B (es) | 2007-07-06 | 2012-11-04 | Basf Se | Metodo para la produccion de una solucion de glucosa acuosa a partir de maiz. |
| JP5534224B2 (ja) * | 2007-07-31 | 2014-06-25 | ディーエスエム アイピー アセッツ ビー.ブイ. | Na−ベータ−アラニネートおよびカルシウムパントテネートの合成方法 |
| JP5524130B2 (ja) * | 2011-05-19 | 2014-06-18 | 武田薬品工業株式会社 | 安定化されたビタミン製剤 |
| CN111093667B (zh) | 2017-07-11 | 2025-10-21 | 合利他命制药株式会社 | 配合维生素b1类的固体制剂 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2864701A (en) * | 1954-04-30 | 1958-12-16 | Merck & Co Inc | Stabilized pantothenic acid compositions |
| US2992273A (en) * | 1958-03-12 | 1961-07-11 | Nopco Chem Co | Preparation of dense calcium pantothenate |
| US3092548A (en) * | 1960-10-27 | 1963-06-04 | Warren Teed Products Company | Method of treating peptic ulcers with pantothenic acid |
| US3247064A (en) * | 1962-03-30 | 1966-04-19 | Shionogi & Co | Multivitamin tablet stabilized with porous silica |
| RO68298A2 (ro) * | 1975-08-05 | 1980-04-15 | Intreprinderea De Medicamente,Ro | Compozitie pe baza de saruri organice de calciu si magneziu usor asimilabile si cu o solubilitate crescuta,si procedeu de preparare a acesteia |
-
1990
- 1990-04-18 US US07/510,686 patent/US5089276A/en not_active Expired - Lifetime
- 1990-04-18 JP JP2103901A patent/JP2891744B2/ja not_active Expired - Fee Related
- 1990-04-18 HU HU902470A patent/HU208626B/hu not_active IP Right Cessation
- 1990-04-19 DE DE90304169T patent/DE69002186T2/de not_active Expired - Lifetime
- 1990-04-19 AT AT90304169T patent/ATE91412T1/de not_active IP Right Cessation
- 1990-04-19 EP EP90304169A patent/EP0394022B1/en not_active Expired - Lifetime
- 1990-04-19 DK DK90304169.7T patent/DK0394022T3/da active
- 1990-04-19 ES ES90304169T patent/ES2058793T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ATE91412T1 (de) | 1993-07-15 |
| HU208626B (en) | 1993-12-28 |
| JPH03123729A (ja) | 1991-05-27 |
| US5089276A (en) | 1992-02-18 |
| JP2891744B2 (ja) | 1999-05-17 |
| DE69002186T2 (de) | 1994-01-27 |
| EP0394022B1 (en) | 1993-07-14 |
| DK0394022T3 (da) | 1993-08-23 |
| HUT54040A (en) | 1991-01-28 |
| EP0394022A1 (en) | 1990-10-24 |
| HU902470D0 (en) | 1990-08-28 |
| DE69002186D1 (de) | 1993-08-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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