ES2059455T3 - Procedimiento para la preparacion de purinas sodicas. - Google Patents
Procedimiento para la preparacion de purinas sodicas.Info
- Publication number
- ES2059455T3 ES2059455T3 ES88113224T ES88113224T ES2059455T3 ES 2059455 T3 ES2059455 T3 ES 2059455T3 ES 88113224 T ES88113224 T ES 88113224T ES 88113224 T ES88113224 T ES 88113224T ES 2059455 T3 ES2059455 T3 ES 2059455T3
- Authority
- ES
- Spain
- Prior art keywords
- sodium
- amino
- purines
- purine
- dihydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000003212 purines Chemical class 0.000 title 1
- BDAGIHXWWSANSR-UHFFFAOYSA-N Formic acid Chemical compound OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 abstract 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- 229910052708 sodium Inorganic materials 0.000 abstract 3
- 239000011734 sodium Substances 0.000 abstract 3
- ZHNUHDYFZUAESO-UHFFFAOYSA-N Formamide Chemical compound NC=O ZHNUHDYFZUAESO-UHFFFAOYSA-N 0.000 abstract 2
- VWDWKYIASSYTQR-UHFFFAOYSA-N sodium nitrate Chemical compound [Na+].[O-][N+]([O-])=O VWDWKYIASSYTQR-UHFFFAOYSA-N 0.000 abstract 2
- GOJUJUVQIVIZAV-UHFFFAOYSA-N 2-amino-4,6-dichloropyrimidine-5-carbaldehyde Chemical compound NC1=NC(Cl)=C(C=O)C(Cl)=N1 GOJUJUVQIVIZAV-UHFFFAOYSA-N 0.000 abstract 1
- PRUGQYWGIVNHEM-UHFFFAOYSA-N 7,9-dihydro-3h-purine-2,8-dione Chemical compound C1=NC(=O)NC2=C1NC(=O)N2 PRUGQYWGIVNHEM-UHFFFAOYSA-N 0.000 abstract 1
- QXNVGIXVLWOKEQ-UHFFFAOYSA-N Disodium Chemical class [Na][Na] QXNVGIXVLWOKEQ-UHFFFAOYSA-N 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 abstract 1
- -1 SODIUM PURINES Chemical class 0.000 abstract 1
- 235000019253 formic acid Nutrition 0.000 abstract 1
- 235000010344 sodium nitrate Nutrition 0.000 abstract 1
- 239000004317 sodium nitrate Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
Abstract
PARA LA OBTENCION DE PURINAS DE SODIO, PRINCIPALMENTE DE 2 AMINO - 9 - DIHIDROXI - 7H - PURINA - 6 - ONA - DISODIO Y 1 - 3 DIHIDROXI - 7H - PURINA - 2,6 - DIONA - SODIO, EN UN EINTOPVERSFAHREN EN ESCALA TECNICA Y ALTO RENDIMIENTO Y ALTO BENEFICIO SE ADICIONA UNA SUSPENSION COMPUESTA DEL CORRESPONDIENTE 4 - AMINO - PIRIMIDIN DERIVADO Y NITRATO SODICO EN FORMAMIDA CON ACIDO FORMICO, ACTO SEGUIDO SE REDUCE, EL PIRIMIDIN DERIVADO 4 - AMINO - 5 - FORMIL - AMINO FORMADO SE CALIENTA A 140 (GRADOS) A 180 (GRADOS) C Y TRAS LA REACCION DEL CICLO DEFINITIVO RESULTANTE SE TRANSPORTA POR EXCESO DE HIDROXIDO SODICO EN LA CORRESPONDIENTE SAL DE SODIO O DE DISODIO, QUE SE SEPARA COMO CRISTALIZADO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19873727508 DE3727508A1 (de) | 1987-08-18 | 1987-08-18 | Verfahren zur herstellung von natriumpurinen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2059455T3 true ES2059455T3 (es) | 1994-11-16 |
Family
ID=6333981
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES88113224T Expired - Lifetime ES2059455T3 (es) | 1987-08-18 | 1988-08-16 | Procedimiento para la preparacion de purinas sodicas. |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0304004B1 (es) |
| JP (1) | JPS6468374A (es) |
| AT (1) | ATE96796T1 (es) |
| DE (2) | DE3727508A1 (es) |
| ES (1) | ES2059455T3 (es) |
| FI (1) | FI92400C (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3928365A1 (de) * | 1989-08-28 | 1991-03-07 | Huels Chemische Werke Ag | Verfahren zur herstellung von reinem guanin |
| US5215947A (en) * | 1990-10-11 | 1993-06-01 | Savoie Refractaires | Refractory parts for devices for regulation or interruption of a jet of steel, made of refractory material |
| DE4136114C2 (de) * | 1991-11-02 | 1995-05-24 | Boehringer Ingelheim Kg | Verbessertes Verfahren zur Herstellung von Guanin und seiner Alkalimetallsalze |
| DE4410678A1 (de) * | 1994-03-28 | 1995-10-05 | Sueddeutsche Kalkstickstoff | Verfahren zur Herstellung von 5-Formylamino-pyrimidinen |
| DE4422587C2 (de) * | 1994-06-28 | 2000-11-30 | Sueddeutsche Kalkstickstoff | Verfahren zur Herstellung von Purinen |
| DE19857949A1 (de) * | 1998-12-16 | 2000-06-21 | Degussa | Verfahren zur Herstellung von Guanin unter Druck |
| CN111646994B (zh) * | 2019-12-13 | 2023-04-18 | 潍坊奥通药业有限公司 | 2,4-二氨基-6-羟基-5-甲酰胺基嘧啶的制备方法及其应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE645713A (es) * | 1963-04-01 | 1964-07-16 | ||
| BE647302A (es) | 1963-04-30 | 1964-08-17 | ||
| JPS5855485A (ja) * | 1981-09-28 | 1983-04-01 | Kohjin Co Ltd | グアニンの精製法 |
-
1987
- 1987-08-18 DE DE19873727508 patent/DE3727508A1/de not_active Withdrawn
-
1988
- 1988-08-16 ES ES88113224T patent/ES2059455T3/es not_active Expired - Lifetime
- 1988-08-16 AT AT88113224T patent/ATE96796T1/de active
- 1988-08-16 EP EP88113224A patent/EP0304004B1/de not_active Revoked
- 1988-08-16 DE DE88113224T patent/DE3885377D1/de not_active Revoked
- 1988-08-17 FI FI883803A patent/FI92400C/fi not_active IP Right Cessation
- 1988-08-18 JP JP63205660A patent/JPS6468374A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6468374A (en) | 1989-03-14 |
| EP0304004B1 (de) | 1993-11-03 |
| FI92400C (fi) | 1994-11-10 |
| FI883803L (fi) | 1989-02-19 |
| DE3727508A1 (de) | 1989-03-02 |
| FI92400B (fi) | 1994-07-29 |
| EP0304004A1 (de) | 1989-02-22 |
| ATE96796T1 (de) | 1993-11-15 |
| DE3885377D1 (de) | 1993-12-09 |
| FI883803A0 (fi) | 1988-08-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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