ES2059624T3 - Un procedimiento para preparar un peptido util como agente antihipertensivo. - Google Patents

Un procedimiento para preparar un peptido util como agente antihipertensivo.

Info

Publication number
ES2059624T3
ES2059624T3 ES89110386T ES89110386T ES2059624T3 ES 2059624 T3 ES2059624 T3 ES 2059624T3 ES 89110386 T ES89110386 T ES 89110386T ES 89110386 T ES89110386 T ES 89110386T ES 2059624 T3 ES2059624 T3 ES 2059624T3
Authority
ES
Spain
Prior art keywords
preparing
procedure
peptide
hypertensive
hypertensive agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89110386T
Other languages
English (en)
Inventor
Tsutomu Mimura
Yasuhiro Kohama
Mikio Nippon Suisan Satake
Yasukazu Nagase
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nissui Corp
Original Assignee
Nippon Suisan Kaisha Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Suisan Kaisha Ltd filed Critical Nippon Suisan Kaisha Ltd
Application granted granted Critical
Publication of ES2059624T3 publication Critical patent/ES2059624T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

UN NUEVO PEPTIDO QUE POSEE EXCELENTE ACTIVIDAD ANTIHIPERTENSORA. EL PEPTIDO TIENE LA FORMULA PRO - THR - HIS ILE - LYS - TRP - GLY - ASP (I), Y PUEDE SER PREPARADO POR PURIFICACION DE UN FLUIDO EXTRAIDO DE TEJIDOS DE PECES O POR COMBINACION DE LOS AMINOACIDOS CONSTITUYENTES POR MEDIO DE UN METODO DE SINTESIS DE PEPTIDOS. MUESTRA EXCELENTE ACTIVIDAD INHIBITORIA DE ACE, BAJA TOXICIDAD, Y BUENA ESTABILIDAD, Y ES ASI UNA SUSTANCIA EXTREMADAMENTE UTIL Y EFECTIVA COMO ANTIHIPERTENSORA.
ES89110386T 1988-06-10 1989-06-08 Un procedimiento para preparar un peptido util como agente antihipertensivo. Expired - Lifetime ES2059624T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP63143258A JPH0778076B2 (ja) 1988-06-10 1988-06-10 新規ペプチド

Publications (1)

Publication Number Publication Date
ES2059624T3 true ES2059624T3 (es) 1994-11-16

Family

ID=15334564

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89110386T Expired - Lifetime ES2059624T3 (es) 1988-06-10 1989-06-08 Un procedimiento para preparar un peptido util como agente antihipertensivo.

Country Status (7)

Country Link
US (1) US5071955A (es)
EP (1) EP0345778B1 (es)
JP (1) JPH0778076B2 (es)
AT (1) ATE94168T1 (es)
AU (1) AU617483B2 (es)
DE (1) DE68908958T2 (es)
ES (1) ES2059624T3 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5977160A (en) * 1992-04-10 1999-11-02 Brigham And Women's Hospital, Inc. Methods for reducing risk of repeat myocardial infarction and increasing survival in heart attack victims
AU2001281464A1 (en) * 2000-03-13 2001-09-24 Monsanto Technology Llc Recombinant proteins containing repeating units
KR100390529B1 (ko) * 2000-04-25 2003-07-04 동원산업 주식회사 참치정소로부터 핵산복합물질을 추출하는 방법 및 이방법에 의해 얻어진 핵산복합물질
KR101961921B1 (ko) * 2017-06-21 2019-03-26 제주대학교 산학협력단 넙치 유래의 항고혈압 펩타이드 및 이를 포함하는 항고혈압용 조성물

Also Published As

Publication number Publication date
EP0345778A1 (en) 1989-12-13
ATE94168T1 (de) 1993-09-15
AU3617489A (en) 1989-12-14
DE68908958T2 (de) 1994-04-21
EP0345778B1 (en) 1993-09-08
JPH01313498A (ja) 1989-12-18
AU617483B2 (en) 1991-11-28
DE68908958D1 (de) 1993-10-14
JPH0778076B2 (ja) 1995-08-23
US5071955A (en) 1991-12-10

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