ES2060189T3 - Procedimiento y sistema biosensor piezoelectrico del crecimiento celular. - Google Patents

Procedimiento y sistema biosensor piezoelectrico del crecimiento celular.

Info

Publication number
ES2060189T3
ES2060189T3 ES90911175T ES90911175T ES2060189T3 ES 2060189 T3 ES2060189 T3 ES 2060189T3 ES 90911175 T ES90911175 T ES 90911175T ES 90911175 T ES90911175 T ES 90911175T ES 2060189 T3 ES2060189 T3 ES 2060189T3
Authority
ES
Spain
Prior art keywords
piezoelectric biosensor
procedure
cell growth
biosensor device
piezoelectric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90911175T
Other languages
English (en)
Inventor
Richard Calvin Ebersole
Robert Paul Foss
Michael David Ward
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EIDP Inc
Original Assignee
EI Du Pont de Nemours and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co
Application granted granted Critical
Publication of ES2060189T3 publication Critical patent/ES2060189T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/806—Electrical property or magnetic property
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/908—Gravimetric analysis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

LA INVENCION SE REFIERE A UN DISPOSITIVO BIOSENSOR PIEZOELECTRICO Y ASI COMO A UN METODO Y UN SISTEMA QUE UTILIZA UN DISPOSITIVO BIOSENSOR PIEZOELECTRICO PARA DETECTAR LOS REQUERIMIENTOS DEL CRECIMIENTO METABOLICO, RESPUESTAS ANTIBIOTICAS Y LOS PRODUCTOS BACTERIANOS ESPECIFICOS DE MICROORGANISMOS. CUANDO UN MICROORGANISMO SE CULTIVA EN UN MEDIO NUTRIENTE APROPIADO QUE CONTIENE UN POLIMERO QUE RESPONDE A LOS METABOLICOS, LOS PRODUCTOS METABOLICOS DEL ORGANISMO ACIDIFICAN EL MEDIO Y PRECIPITAN UN COMPLEJO DE POLIMERO Y METABOLITO QUE SE DEPOSITA O ACUMULA SOBRE LA SUPERFICIE DE UN DISPOSITIVO BIOSENSOR PIEZOELECTRICO. EL CAMBIO DE MASA SOBRE LA SUPERFICIE DEL DISPOSITIVO RESULTANTE DE ESTE DEPOSITO PRODUCE UN CAMBIO EN LA FRECUENCIA RESONANTE DEL DISPOSITIVO BIOSENSOR PIEZOELECTRICO QUE SE PUEDE UTILIZAR PARA DETERMINAR EL CRECIMIENTO Y EL TIPO DE MICROORGANISMO.
ES90911175T 1989-07-25 1990-06-25 Procedimiento y sistema biosensor piezoelectrico del crecimiento celular. Expired - Lifetime ES2060189T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/384,813 US5135852A (en) 1989-07-25 1989-07-25 Piezoelectric cell growth biosensing method using polymer-metabolic product complex interactions

Publications (1)

Publication Number Publication Date
ES2060189T3 true ES2060189T3 (es) 1994-11-16

Family

ID=23518864

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90911175T Expired - Lifetime ES2060189T3 (es) 1989-07-25 1990-06-25 Procedimiento y sistema biosensor piezoelectrico del crecimiento celular.

Country Status (9)

Country Link
US (1) US5135852A (es)
EP (1) EP0484384B1 (es)
JP (1) JPH04506898A (es)
AT (1) ATE94909T1 (es)
CA (1) CA2064188A1 (es)
DE (1) DE69003535T2 (es)
DK (1) DK0484384T3 (es)
ES (1) ES2060189T3 (es)
WO (1) WO1991001381A1 (es)

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US5306644A (en) * 1988-09-29 1994-04-26 Hewlett-Packard Company Mass sensor method for measuring analytes in a sample
DE69010506T2 (de) * 1989-10-04 1994-12-22 Du Pont Bestimmungsverfahren für biologische zielkomplexe auf der oberfläche eines biosensors.
US5312734A (en) * 1991-09-20 1994-05-17 The United States Of America As Represented By The Department Of Health And Human Services CDNA encoding a dopamine transporter
US20010021513A1 (en) * 1991-11-21 2001-09-13 Puijk Wouter Cornelis Test device comprising a plate containing a multiplicity of wells with an associated metering device, as well as a kit which comprises these devices and use of the devices
DE69309468T2 (de) * 1992-07-17 1997-09-04 Du Pont Nachweis eines Analyten mittels eines Analyt-sensitiven Polymers
DE4334834A1 (de) * 1993-10-13 1995-04-20 Andrzej Dr Ing Grzegorzewski Biosensor zum Messen von Viskositäts- und/oder Dichteänderungen
US5705399A (en) * 1994-05-20 1998-01-06 The Cooper Union For Advancement Of Science And Art Sensor and method for detecting predetermined chemical species in solution
US6053032A (en) * 1995-04-13 2000-04-25 Nalco Chemical Company System and method for determining a deposition rate in a process stream indicative of a mass build-up and for controlling feed of a product in the process stream to combat same
FR2739448B1 (fr) * 1995-09-29 1997-10-24 Thomson Csf Dispositif de detection et de controle de biofilms
US6118124A (en) * 1996-01-18 2000-09-12 Lockheed Martin Energy Research Corporation Electromagnetic and nuclear radiation detector using micromechanical sensors
IL120445A0 (en) * 1997-03-13 1997-07-13 Yissum Res Dev Co Biosensor for cells
SE9701007L (sv) * 1997-03-17 1998-09-18 Michael Rodahl Förfarande vid en piezoelektrisk kristallmikrovågsmätning
US6016686A (en) * 1998-03-16 2000-01-25 Lockheed Martin Energy Research Corporation Micromechanical potentiometric sensors
US6167748B1 (en) 1998-08-31 2001-01-02 Lockheed Martin Energy Research Corporation Capacitively readout multi-element sensor array with common-mode cancellation
US6289717B1 (en) 1999-03-30 2001-09-18 U. T. Battelle, Llc Micromechanical antibody sensor
JP2003507723A (ja) * 1999-08-19 2003-02-25 ザ・リージェンツ・オブ・ザ・ユニバーシティー・オブ・カリフォルニア カンチレバーアレイブロックのパレットにより微小力を可視的に識別する装置及び方法
US7148017B1 (en) * 2000-07-12 2006-12-12 Cornell Research Foundation, Inc. High sensitivity mechanical resonant sensor
US9274101B2 (en) * 2001-04-20 2016-03-01 Biolog, Inc. Methods and kits for obtaining a metabolic profile of living animal cells
US20030162164A1 (en) * 2001-04-20 2003-08-28 Biolog, Inc. Comparative phenotype analysis of cells, including testing of biologically active compounds
US20030154149A1 (en) * 2002-02-13 2003-08-14 Dilip Gajendragadkar System and method of creating and executing a restricted stock sale plan
DE10209245B4 (de) * 2002-03-04 2005-12-22 Concentris Gmbh Vorrichtung und Verfahren zur Detektion von Mikroorganismen
US20040234954A1 (en) * 2003-03-03 2004-11-25 Klaus Nusslein Surfaces that selectively bind to moieties
US20080138797A1 (en) * 2003-11-13 2008-06-12 Hunt William D Detection Systems and Methods
US20050148065A1 (en) 2003-12-30 2005-07-07 Intel Corporation Biosensor utilizing a resonator having a functionalized surface
US7274835B2 (en) * 2004-02-18 2007-09-25 Cornell Research Foundation, Inc. Optical waveguide displacement sensor
US20060217893A1 (en) * 2005-01-07 2006-09-28 Yanbin Li Method for detecting an unknown contaminant concentration in a substance
WO2008028124A1 (en) * 2006-09-01 2008-03-06 The Board Of Trustees Of The University Of Arkansas Methods and systems for detection of contaminants
US20080245135A1 (en) * 2006-11-15 2008-10-09 Cornell Research Foundation, Inc. Microfluidic encapsulated nems resonators
DE102007053221B4 (de) * 2007-11-06 2015-08-20 Endress + Hauser Gmbh + Co. Kg Verfahren zur Bestimmung und/oder Überwachung des Wachstums einer biologischen Substanz in einem Medium
US7802466B2 (en) * 2007-11-28 2010-09-28 Sierra Sensors Gmbh Oscillating sensor and fluid sample analysis using an oscillating sensor
US8133356B2 (en) * 2008-06-19 2012-03-13 Nalco Company Method of monitoring microbiological deposits
US8459123B2 (en) * 2008-06-19 2013-06-11 The United States Of America, As Represented By The Secretary Of The Navy Micromechanical chemical sensors with multiple chemoselective resonant elements and frequency division multiplexed readout
US7964144B1 (en) * 2010-01-14 2011-06-21 International Islamic University Malaysia MEMS biosensor with integrated impedance and mass-sensing capabilities
JP5231495B2 (ja) * 2010-03-10 2013-07-10 日本電波工業株式会社 微生物の検出方法及び微生物検出装置
EP2630479B1 (en) 2010-10-20 2020-04-08 Qorvo US, Inc. Apparatus and method for measuring binding kinetics and concentration with a resonating sensor
FR2976673B1 (fr) * 2011-06-16 2014-02-14 Univ Cergy Pontoise Capteur piezo-electrique pour la detection et la caracterisation d'au moins un element biochimique.
JP2013031408A (ja) * 2011-08-03 2013-02-14 Sony Corp 電気応答性機能材料を用いた細胞培養デバイス
US20160296945A1 (en) 2013-03-15 2016-10-13 Ancera, Inc. Systems and methods for active particle separation
WO2014145765A1 (en) 2013-03-15 2014-09-18 Ancera, Inc. Systems and methods for bead-based assays in ferrofluids
US11285490B2 (en) 2015-06-26 2022-03-29 Ancera, Llc Background defocusing and clearing in ferrofluid-based capture assays
US9725752B2 (en) * 2015-08-13 2017-08-08 The United States Of America, As Represented By The Secretary Of Commerce Resonator and process for performing biological assay
US10670566B2 (en) 2015-11-20 2020-06-02 Drexel University Rapid antimicrobial susceptibility testing using piezoelectric sensor
CN114075510A (zh) * 2020-08-14 2022-02-22 上海必修福企业管理有限公司 影响生物体生长的装置及其用途及影响生物体生长的方法

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FR2396974A1 (fr) * 1977-07-04 1979-02-02 Anvar Procede de detection et d'etude d'une activite cellulaire ou analogue et moyens pour la mise en oeuvre d'un tel procede
US4242096A (en) * 1977-11-14 1980-12-30 Minnesota Mining And Manufacturing Company Immunoassay for antigens
US4236893A (en) * 1979-04-09 1980-12-02 Minnesota Mining And Manufacturing Company Method for the assay of classes of antigen-specific antibodies
US4314821A (en) * 1979-04-09 1982-02-09 Minnesota Mining And Manufacturing Company Sandwich immunoassay using piezoelectric oscillator
US4735906A (en) * 1984-11-28 1988-04-05 Texas A&M University Sensor having piezoelectric crystal for microgravimetric immunoassays
EP0215669A3 (en) * 1985-09-17 1989-08-30 Seiko Instruments Inc. Analytical device and method for analysis of biochemicals, microbes and cells
JPS63501920A (ja) * 1985-09-26 1988-08-04 ザ・ユニバ−シティ−・オブ・サザン・ミシシッピ ポリヌクレオチド・ハイブリダイゼ−ション検知用圧電性デバイス
IL85137A (en) * 1987-01-21 1992-02-16 Ares Serono Res & Dev Ltd Method of assaying for a ligand using surface plasmon resonance effect
US4847193A (en) * 1987-06-18 1989-07-11 Gene-Trak Systems Signal amplification in an assay employing a piezoelectric oscillator
US4999284A (en) * 1988-04-06 1991-03-12 E. I. Du Pont De Nemours And Company Enzymatically amplified piezoelectric specific binding assay

Also Published As

Publication number Publication date
ATE94909T1 (de) 1993-10-15
EP0484384B1 (en) 1993-09-22
EP0484384A1 (en) 1992-05-13
DE69003535T2 (de) 1994-02-10
WO1991001381A1 (en) 1991-02-07
JPH04506898A (ja) 1992-12-03
US5135852A (en) 1992-08-04
CA2064188A1 (en) 1991-01-26
DE69003535D1 (de) 1993-10-28
DK0484384T3 (da) 1993-11-29

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