ES2060825T3 - Un sistema terapeutico para el administracion retardada y controlada de sustancias activas por via percutanea o a traves de la mucosa. - Google Patents

Un sistema terapeutico para el administracion retardada y controlada de sustancias activas por via percutanea o a traves de la mucosa.

Info

Publication number
ES2060825T3
ES2060825T3 ES90102770T ES90102770T ES2060825T3 ES 2060825 T3 ES2060825 T3 ES 2060825T3 ES 90102770 T ES90102770 T ES 90102770T ES 90102770 T ES90102770 T ES 90102770T ES 2060825 T3 ES2060825 T3 ES 2060825T3
Authority
ES
Spain
Prior art keywords
delayed
therapeutic system
percutanea
mucosa
active substances
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90102770T
Other languages
English (en)
Inventor
Walter Dr Dipl-Chem Muller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LTS Lohmann Therapie Systeme AG
Original Assignee
LTS Lohmann Therapie Systeme AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LTS Lohmann Therapie Systeme AG filed Critical LTS Lohmann Therapie Systeme AG
Application granted granted Critical
Publication of ES2060825T3 publication Critical patent/ES2060825T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Furan Compounds (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Steroid Compounds (AREA)

Abstract

SE HA INVENTADO UN SISTEMA TERAPEUTICO PARA EL SUMINISTRO TRANSDERMAL O TRANSMUCOSAL RETARDADO Y CONTROLADO DE SUSTANCIAS ACTIVADORAS QUE SE COMPONE DE UNA CAPA TRASERA IMPERMEABLE, UN DEPOSITO DE SUSTANCIAS AUXILIARES, UN DEPOSITO DE SUSTANCIAS ACTIVADORAS Y UNA CAPA PROTECTORA DESPRENDIBLE. EL DEPOSITO DE SUSTANCIAS ACTIVADORAS CONTIENE UNA SUSTANCIA EN ESTADO NO BIODISPONIBLE. LA SUSTANCIA AUXILIAR DEL CORRESPONDIENTE DEPOSITO TRANSFORMA LA SUSTANCIA ACTIVADORA HACIENDOLA BIODISPONIBLE. LOS DEPOSITOS DE SUSTANCIAS AUXILIARES Y SUSTANCIAS ACTIVADORAS SE CONECTAN SOLO INMEDIATAMENTE ANTES, O BIEN EN ALGUN MOMENTO DESPUES DE LA APLICACION, DE TAL MANERA QUE LA SUSTANCIA AUXILIAR ENTRE EN EL DEPOSITO DE SUSTANCIAS ACTIVADORAS.
ES90102770T 1989-02-18 1990-02-13 Un sistema terapeutico para el administracion retardada y controlada de sustancias activas por via percutanea o a traves de la mucosa. Expired - Lifetime ES2060825T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3905050A DE3905050A1 (de) 1989-02-18 1989-02-18 Therapeutisches system zur verzoegerten und gesteuerten transdermalen oder transmucosalen verabreichung von wirkstoffen (ii)

Publications (1)

Publication Number Publication Date
ES2060825T3 true ES2060825T3 (es) 1994-12-01

Family

ID=6374442

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90102770T Expired - Lifetime ES2060825T3 (es) 1989-02-18 1990-02-13 Un sistema terapeutico para el administracion retardada y controlada de sustancias activas por via percutanea o a traves de la mucosa.

Country Status (15)

Country Link
US (1) US5466466A (es)
EP (1) EP0384266B1 (es)
JP (1) JP2552190B2 (es)
AT (1) ATE108680T1 (es)
AU (1) AU627268B2 (es)
CA (1) CA2010218C (es)
DD (1) DD291928A5 (es)
DE (2) DE3905050A1 (es)
DK (1) DK0384266T3 (es)
ES (1) ES2060825T3 (es)
FI (1) FI105157B (es)
IE (1) IE66739B1 (es)
NO (1) NO303207B1 (es)
PT (1) PT93191B (es)
ZA (1) ZA901183B (es)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT65957A (en) † 1992-03-17 1994-08-29 Becton Dickinson Co User operated iontophoretical device and method for manufacturing it
US5730721A (en) 1996-01-25 1998-03-24 Vesture Corporation Medical applicator and method
DE19653606A1 (de) * 1996-12-20 1998-06-25 Roehm Gmbh Haft- und Bindemittel aus (Meth)acrylatpolymer, organischer Säure und Weichmacher
US5912255A (en) * 1998-02-27 1999-06-15 Bussell; Letantia Topical fluoroquinolone antibiotics combined with benzoyl peroxide
DE19814087A1 (de) * 1998-03-30 1999-10-14 Lohmann Therapie Syst Lts Feuchtigkeitsaktivierbares therapeutisches System
DE19814083C2 (de) 1998-03-30 2002-02-07 Lohmann Therapie Syst Lts Verfahren zur Herstellung von transdermalen therapeutischen Systemen unter Verwendung von basischen Alkalimetallsalzen zur Umwandlung von Wirkstoffsalzen in die freien Basen
US6416777B1 (en) 1999-10-21 2002-07-09 Alcon Universal Ltd. Ophthalmic drug delivery device
ATE283013T1 (de) 1999-10-21 2004-12-15 Alcon Inc Medikamentenzuführvorrichtung
PT1221918E (pt) 1999-10-21 2005-06-30 Alcon Inc Administracao de drogas sub-tenon
US7943162B2 (en) * 1999-10-21 2011-05-17 Alcon, Inc. Drug delivery device
US20060189552A1 (en) * 2000-12-12 2006-08-24 Mohan Vishnupad Dispenser for dispensing three or more actives
US7060732B2 (en) * 2000-12-12 2006-06-13 Imaginative Research Associates, Inc. Antibiotic/benzoyl peroxide dispenser
US20020193321A1 (en) * 2000-12-12 2002-12-19 Mohan Vishnupad Dual dispenser for aesthitically acceptable delivery of anhydrous skin treatment compositions
WO2002089767A1 (en) 2001-05-03 2002-11-14 Massachusetts Eye And Ear Infirmary Implantable drug delivery device and use thereof
DE60214697T2 (de) * 2001-07-23 2007-09-13 Alcon Inc. Vorrichtung zur freisetzung eines ophthalmischen arzneimittels
DE60217679T2 (de) 2001-07-23 2007-10-25 Alcon Inc. Vorrichtung zur freisetzung eines ophthalmischen arzneimittels
KR20060082792A (ko) * 2003-07-10 2006-07-19 알콘, 인코퍼레이티드 안과용 약물 전달 장치
MEP23508A (en) * 2003-10-28 2010-06-10 Noven Pharma Compositions and methods for comtrolling drug loss and delivery in transdermal drug delivery systems
US7662855B2 (en) * 2004-05-11 2010-02-16 Imaginative Research Associates, Inc. Retinoid solutions and formulations made therefrom
US20060014834A1 (en) * 2004-05-11 2006-01-19 Mohan Vishnupad Retinoid solutions and formulations made therefrom
DE102004062614B4 (de) * 2004-12-24 2011-12-29 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System mit aktivierbarer Übersättigung und kontrollierter Permeationförderung sowie Verfahren zu dessen Herstellung
WO2006082728A1 (ja) * 2005-02-04 2006-08-10 Hisamitsu Pharmaceutical Co., Inc. 経皮吸収貼付剤
AU2006272497B2 (en) 2005-07-27 2012-07-19 University Of Florida Research Foundation, Inc. Small compounds that correct protein misfolding and uses thereof
HRP20100559T1 (hr) 2005-11-29 2010-11-30 Glaxosmithkline Llc Liječenje neovaskularnih poremećaja oka, poput makularne degeneracije, angioidnih strija, uveitisa i edema makule
TWI498136B (zh) * 2007-10-09 2015-09-01 Alcon Res Ltd 用於遞送速率及溫度相依性物質至眼睛的注射器及其製備方法
TWI451862B (zh) * 2007-10-09 2014-09-11 Alcon Res Ltd 用於眼睛注射的熱係數驅動藥丸尺寸
DE102008013701A1 (de) 2008-03-11 2009-09-17 Lts Lohmann Therapie-Systeme Ag Transdermales Therapeutisches System mit stabilisierter Membran
US8372036B2 (en) 2009-05-06 2013-02-12 Alcon Research, Ltd. Multi-layer heat assembly for a drug delivery device
IN2012DN00352A (es) 2009-06-16 2015-08-21 Bikam Pharmaceuticals Inc
US20120232102A1 (en) 2009-09-30 2012-09-13 Chun-Fang Xu Methods Of Administration And Treatment
US8177747B2 (en) 2009-12-22 2012-05-15 Alcon Research, Ltd. Method and apparatus for drug delivery
EP2700401B1 (en) 2011-04-18 2020-01-15 Hisamitsu Pharmaceutical Co., Inc. Method for producing adhesive patch, and adhesive patch
EA032666B1 (ru) 2011-06-14 2019-06-28 Бикам Фармасьютикалз, Инк. Опсинсвязывающие лиганды и способы их применения
CA2856703A1 (en) 2011-10-19 2013-04-25 Bikam Pharmaceuticals, Inc. Opsin-binding ligands, compositions and methods of use
AU2012346214B2 (en) 2011-11-30 2017-09-14 Bikam Pharmaceuticals, Inc. Opsin-binding ligands, compositions and methods of use
JP6322142B2 (ja) 2011-12-01 2018-05-09 ビカム ファーマスーティカルス，インコーポレイテッド オプシン結合性リガンド、組成物、及び使用方法
US20240374599A1 (en) 2020-02-26 2024-11-14 Case Western Reserve University Compositions and methods for treating misfolded protein ocular disorders

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405616A (en) 1975-06-19 1983-09-20 Nelson Research & Development Company Penetration enhancers for transdermal drug delivery of systemic agents
US4756710A (en) * 1985-04-05 1988-07-12 Merck & Co., Inc. pH-Mediated drug delivery system
EP0249475A3 (en) 1986-06-13 1989-10-11 Alza Corporation Delayed percutaneous delivery
DE3775830D1 (de) 1986-06-13 1992-02-20 Alza Corp Aktivierung eines transdermalen drogenabgabesystems durch feuchtigkeit.
EP0290262A3 (en) * 1987-05-08 1990-12-12 EASTMAN KODAK COMPANY (a New Jersey corporation) Improved nitrate therapy for angina pectoris
US4781924A (en) * 1987-11-09 1988-11-01 Alza Corporation Transdermal drug delivery device

Also Published As

Publication number Publication date
PT93191B (pt) 1998-01-30
JPH03197420A (ja) 1991-08-28
DD291928A5 (de) 1991-07-18
IE900580L (en) 1990-08-18
AU4877090A (en) 1990-08-23
CA2010218A1 (en) 1990-08-18
DE3905050A1 (de) 1990-08-30
DE59006461D1 (de) 1994-08-25
FI105157B (fi) 2000-06-30
EP0384266A2 (de) 1990-08-29
EP0384266A3 (en) 1990-11-22
FI900740A0 (fi) 1990-02-14
ATE108680T1 (de) 1994-08-15
US5466466A (en) 1995-11-14
CA2010218C (en) 1998-04-28
NO900748D0 (no) 1990-02-16
NO900748L (no) 1990-08-20
JP2552190B2 (ja) 1996-11-06
NO303207B1 (no) 1998-06-15
ZA901183B (en) 1990-11-28
PT93191A (pt) 1990-08-31
AU627268B2 (en) 1992-08-20
DE3905050C2 (es) 1991-08-08
IE66739B1 (en) 1996-02-07
DK0384266T3 (da) 1994-11-21
EP0384266B1 (de) 1994-07-20

Similar Documents

Publication Publication Date Title
ES2060825T3 (es) Un sistema terapeutico para el administracion retardada y controlada de sustancias activas por via percutanea o a traves de la mucosa.
IT8719064A0 (it) Compressa per uso farmaceutico atta al rilascio in tempi successivi di sostanze attive.
ECSP941148A (es) Medicamento en forma de comprimido con liberacion retardada de substancia activa
NO883837L (no) Anordning til avgivelse av et middel i et foerste tidsrom etterfulgt av et andre, lengre tidsrom.
MX9202407A (es) Composicion farmaceutica que contiene un compuesto de alilamina como el agente activo y proceso para su preparacion.
AR005282A1 (es) Composición farmacéutica oral en la forma de un comprimido de unidades múltiples, uso de la misma para la preparación de medicamnetos, y procedimiento para su manufactura.
ATE94390T1 (de) Orale darreichungsformen mit verzoegerter abgabe.
ES2157944T3 (es) Nucleos de pastillas de liberacion inmediata de medicamentos insolubles que poseen un recubrimiento de liberacion sostenida.
MX9207263A (es) Sistema para el suministro de una substancia activa para la liberacion sostenida.
ES2195308T3 (es) Composicon farmaceutica de fenofibrato que presenta una biodisponibilidad elevada, y metodo para su preparacion.
EP0221732A3 (en) Sustained release tablets
ATE427103T1 (de) Orale verabreichung von adenosin analogen
IS1565B (is) Aðferð við framleiðslu á N1-súbstitúeruðum bensimidasólafleiðum til að nota við lækningar
AR004700A1 (es) 1alfa, 26 dihidroxi-d-homo-vitamina d3, una composicion farmaceutica que la comprende, un procedimiento para su preparacion y el uso de los mismos en laelaboracion de un medicamento
ATE311227T1 (de) Schnell-wirkende, gefrier-trocknete, orale, pharmazeutische formulierung für die behandlung von migräne
CL2008003939A1 (es) Uso de escitalopram o una sal farmaceuticamente aceptable del mismo para preparar un medicamento util en el tratamiento de ansiedad social (divisional de la solicitud 1799-00).
TR199801861T2 (xx) Farmas�tik olarak yararl� bile�imler.
MX174161B (es) Una forma de dosis para suministrar el farmaco benefico verapamil
AR006401A1 (es) Compuestos de pirrolopirrolona, una composicion farmaceutica que los contiene, su uso en la fabricacion de un medicamento y en terapia, procesospara su preparación y compuestos intermediarios para dichos procesos.
ES2029228T3 (es) Procedimiento para la produccion de un preparado retardado de ibuprofeno.
ES2193233T3 (es) Uso de amiodipina, una sal de la misma o felodipina en combinacion con un inhibidor ace en la fabricacion de un medicamento para el tratamiento de insuficiencia cardiaca conjuntiva no isquemica.
MX9205568A (es) Composicion farmaceutica que contiene cantidades de 5-amino-1beta-d-ribofuranosil-imidazol-4-carboxamida.
UY25798A1 (es) Composición farmacéutica de liberación modificada que comprende un sensibilizador de insulina tiazolidinadiónico.
BR9608255A (pt) Sistema terapéutico transdérmico (stt) para a administração de testosterona
AR022621A1 (es) Composicion farmaceutica que contiene desoxipeganina para el tratamiento de la dependencia de la nicotina

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 384266

Country of ref document: ES