ES2060825T3 - Un sistema terapeutico para el administracion retardada y controlada de sustancias activas por via percutanea o a traves de la mucosa. - Google Patents

Un sistema terapeutico para el administracion retardada y controlada de sustancias activas por via percutanea o a traves de la mucosa.

Info

Publication number
ES2060825T3
ES2060825T3 ES90102770T ES90102770T ES2060825T3 ES 2060825 T3 ES2060825 T3 ES 2060825T3 ES 90102770 T ES90102770 T ES 90102770T ES 90102770 T ES90102770 T ES 90102770T ES 2060825 T3 ES2060825 T3 ES 2060825T3
Authority
ES
Spain
Prior art keywords
delayed
therapeutic system
percutanea
mucosa
active substances
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90102770T
Other languages
English (en)
Inventor
Walter Dr Dipl-Chem Muller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LTS Lohmann Therapie Systeme AG
Original Assignee
LTS Lohmann Therapie Systeme AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LTS Lohmann Therapie Systeme AG filed Critical LTS Lohmann Therapie Systeme AG
Application granted granted Critical
Publication of ES2060825T3 publication Critical patent/ES2060825T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Furan Compounds (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Steroid Compounds (AREA)

Abstract

SE HA INVENTADO UN SISTEMA TERAPEUTICO PARA EL SUMINISTRO TRANSDERMAL O TRANSMUCOSAL RETARDADO Y CONTROLADO DE SUSTANCIAS ACTIVADORAS QUE SE COMPONE DE UNA CAPA TRASERA IMPERMEABLE, UN DEPOSITO DE SUSTANCIAS AUXILIARES, UN DEPOSITO DE SUSTANCIAS ACTIVADORAS Y UNA CAPA PROTECTORA DESPRENDIBLE. EL DEPOSITO DE SUSTANCIAS ACTIVADORAS CONTIENE UNA SUSTANCIA EN ESTADO NO BIODISPONIBLE. LA SUSTANCIA AUXILIAR DEL CORRESPONDIENTE DEPOSITO TRANSFORMA LA SUSTANCIA ACTIVADORA HACIENDOLA BIODISPONIBLE. LOS DEPOSITOS DE SUSTANCIAS AUXILIARES Y SUSTANCIAS ACTIVADORAS SE CONECTAN SOLO INMEDIATAMENTE ANTES, O BIEN EN ALGUN MOMENTO DESPUES DE LA APLICACION, DE TAL MANERA QUE LA SUSTANCIA AUXILIAR ENTRE EN EL DEPOSITO DE SUSTANCIAS ACTIVADORAS.
ES90102770T 1989-02-18 1990-02-13 Un sistema terapeutico para el administracion retardada y controlada de sustancias activas por via percutanea o a traves de la mucosa. Expired - Lifetime ES2060825T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3905050A DE3905050A1 (de) 1989-02-18 1989-02-18 Therapeutisches system zur verzoegerten und gesteuerten transdermalen oder transmucosalen verabreichung von wirkstoffen (ii)

Publications (1)

Publication Number Publication Date
ES2060825T3 true ES2060825T3 (es) 1994-12-01

Family

ID=6374442

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90102770T Expired - Lifetime ES2060825T3 (es) 1989-02-18 1990-02-13 Un sistema terapeutico para el administracion retardada y controlada de sustancias activas por via percutanea o a traves de la mucosa.

Country Status (15)

Country Link
US (1) US5466466A (es)
EP (1) EP0384266B1 (es)
JP (1) JP2552190B2 (es)
AT (1) ATE108680T1 (es)
AU (1) AU627268B2 (es)
CA (1) CA2010218C (es)
DD (1) DD291928A5 (es)
DE (2) DE3905050A1 (es)
DK (1) DK0384266T3 (es)
ES (1) ES2060825T3 (es)
FI (1) FI105157B (es)
IE (1) IE66739B1 (es)
NO (1) NO303207B1 (es)
PT (1) PT93191B (es)
ZA (1) ZA901183B (es)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT65957A (en) † 1992-03-17 1994-08-29 Becton Dickinson Co User operated iontophoretical device and method for manufacturing it
US5730721A (en) 1996-01-25 1998-03-24 Vesture Corporation Medical applicator and method
DE19653606A1 (de) * 1996-12-20 1998-06-25 Roehm Gmbh Haft- und Bindemittel aus (Meth)acrylatpolymer, organischer Säure und Weichmacher
US5912255A (en) * 1998-02-27 1999-06-15 Bussell; Letantia Topical fluoroquinolone antibiotics combined with benzoyl peroxide
DE19814083C2 (de) 1998-03-30 2002-02-07 Lohmann Therapie Syst Lts Verfahren zur Herstellung von transdermalen therapeutischen Systemen unter Verwendung von basischen Alkalimetallsalzen zur Umwandlung von Wirkstoffsalzen in die freien Basen
DE19814087A1 (de) * 1998-03-30 1999-10-14 Lohmann Therapie Syst Lts Feuchtigkeitsaktivierbares therapeutisches System
US7943162B2 (en) * 1999-10-21 2011-05-17 Alcon, Inc. Drug delivery device
US6416777B1 (en) * 1999-10-21 2002-07-09 Alcon Universal Ltd. Ophthalmic drug delivery device
CA2383499C (en) * 1999-10-21 2009-11-24 Alcon Universal Ltd. Drug delivery device
JP2003511204A (ja) 1999-10-21 2003-03-25 アルコン，インコーポレイティド テノン下薬剤送出
US7060732B2 (en) * 2000-12-12 2006-06-13 Imaginative Research Associates, Inc. Antibiotic/benzoyl peroxide dispenser
US20060189552A1 (en) * 2000-12-12 2006-08-24 Mohan Vishnupad Dispenser for dispensing three or more actives
US20020193321A1 (en) * 2000-12-12 2002-12-19 Mohan Vishnupad Dual dispenser for aesthitically acceptable delivery of anhydrous skin treatment compositions
EP1387671A1 (en) 2001-05-03 2004-02-11 MASSACHUSETTS EYE & EAR INFIRMARY Implantable drug delivery device and use thereof
AU2002319606B2 (en) * 2001-07-23 2006-09-14 Alcon, Inc. Ophthalmic drug delivery device
WO2003009774A2 (en) 2001-07-23 2003-02-06 Alcon, Inc. Ophthalmic drug delivery device
KR20060082792A (ko) * 2003-07-10 2006-07-19 알콘, 인코퍼레이티드 안과용 약물 전달 장치
CA2542778C (en) * 2003-10-28 2012-05-29 Noven Pharmaceuticals, Inc. Transdermal drug delivery composition
US7662855B2 (en) * 2004-05-11 2010-02-16 Imaginative Research Associates, Inc. Retinoid solutions and formulations made therefrom
US20060014834A1 (en) * 2004-05-11 2006-01-19 Mohan Vishnupad Retinoid solutions and formulations made therefrom
DE102004062614B4 (de) * 2004-12-24 2011-12-29 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System mit aktivierbarer Übersättigung und kontrollierter Permeationförderung sowie Verfahren zu dessen Herstellung
US20080138388A1 (en) * 2005-02-04 2008-06-12 Hisamitsu Pharmaceutical Co., Inc. Transdermal Absorption Patch
US20100004156A1 (en) 2005-07-27 2010-01-07 Shalesh Kaushal Small Compounds That Correct Protein Misfolding and Uses Thereof
EA016227B1 (ru) 2005-11-29 2012-03-30 Смитклайн Бичем Корпорейшн Способ лечения офтальмологических неоваскулярных расстройств
TWI451862B (zh) * 2007-10-09 2014-09-11 Alcon Res Ltd 用於眼睛注射的熱係數驅動藥丸尺寸
TWI498136B (zh) * 2007-10-09 2015-09-01 Alcon Res Ltd 用於遞送速率及溫度相依性物質至眼睛的注射器及其製備方法
DE102008013701A1 (de) 2008-03-11 2009-09-17 Lts Lohmann Therapie-Systeme Ag Transdermales Therapeutisches System mit stabilisierter Membran
US8632511B2 (en) 2009-05-06 2014-01-21 Alcon Research, Ltd. Multiple thermal sensors in a multiple processor environment for temperature control in a drug delivery device
IN2012DN00352A (es) 2009-06-16 2015-08-21 Bikam Pharmaceuticals Inc
US20120232102A1 (en) 2009-09-30 2012-09-13 Chun-Fang Xu Methods Of Administration And Treatment
US8177747B2 (en) 2009-12-22 2012-05-15 Alcon Research, Ltd. Method and apparatus for drug delivery
CA2833474C (en) 2011-04-18 2017-09-19 Hisamitsu Pharmaceutical Co., Inc. Method for producing patch, and patch
US9133082B2 (en) 2011-06-14 2015-09-15 Bikam Pharmaceuticals, Inc. Opsin-binding ligands, compositions and methods of use
CA2856703A1 (en) 2011-10-19 2013-04-25 Bikam Pharmaceuticals, Inc. Opsin-binding ligands, compositions and methods of use
WO2013082000A1 (en) 2011-11-30 2013-06-06 Bikam Pharmaceuticals, Inc. Opsin-binding ligands, compositions and methods of use
AU2012346537A1 (en) 2011-12-01 2014-07-17 Bikam Pharmaceuticals, Inc. Opsin-binding ligands, compositions and methods of use
AU2021225926A1 (en) 2020-02-26 2022-10-20 Case Western Reserve University Compositions and methods for treating misfolded protein ocular disorders

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405616A (en) 1975-06-19 1983-09-20 Nelson Research & Development Company Penetration enhancers for transdermal drug delivery of systemic agents
US4756710A (en) * 1985-04-05 1988-07-12 Merck & Co., Inc. pH-Mediated drug delivery system
DE3775830D1 (de) 1986-06-13 1992-02-20 Alza Corp Aktivierung eines transdermalen drogenabgabesystems durch feuchtigkeit.
EP0249475A3 (en) 1986-06-13 1989-10-11 Alza Corporation Delayed percutaneous delivery
JPS6425717A (en) * 1987-05-08 1989-01-27 Eastman Kodak Co Method and apparatus for preventing organic nitric acid ester resistance
US4781924A (en) * 1987-11-09 1988-11-01 Alza Corporation Transdermal drug delivery device

Also Published As

Publication number Publication date
FI900740A0 (fi) 1990-02-14
PT93191A (pt) 1990-08-31
DE59006461D1 (de) 1994-08-25
ATE108680T1 (de) 1994-08-15
IE66739B1 (en) 1996-02-07
EP0384266B1 (de) 1994-07-20
DD291928A5 (de) 1991-07-18
DE3905050C2 (es) 1991-08-08
EP0384266A2 (de) 1990-08-29
AU4877090A (en) 1990-08-23
CA2010218A1 (en) 1990-08-18
JPH03197420A (ja) 1991-08-28
AU627268B2 (en) 1992-08-20
NO900748L (no) 1990-08-20
PT93191B (pt) 1998-01-30
FI105157B (fi) 2000-06-30
IE900580L (en) 1990-08-18
DK0384266T3 (da) 1994-11-21
NO303207B1 (no) 1998-06-15
EP0384266A3 (en) 1990-11-22
ZA901183B (en) 1990-11-28
JP2552190B2 (ja) 1996-11-06
CA2010218C (en) 1998-04-28
DE3905050A1 (de) 1990-08-30
NO900748D0 (no) 1990-02-16
US5466466A (en) 1995-11-14

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